{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T10:14:29Z","timestamp":1779963269723,"version":"3.53.1"},"reference-count":39,"publisher":"Charles University in Prague, Karolinum Press","issue":"3","license":[{"start":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T00:00:00Z","timestamp":1675296000000},"content-version":"vor","delay-in-days":397,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T00:00:00Z","timestamp":1675296000000},"content-version":"tdm","delay-in-days":397,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["actamedica.lfhk.cuni.cz"],"crossmark-restriction":true},"short-container-title":["Acta Med. (Hradec Kralove, Czech Repub.)"],"published-print":{"date-parts":[[2022]]},"abstract":"<jats:p>Purpose: To characterize choroidal structure and vasculature after half-dose verteporfin photodynamic therapy (hd-vPDT) in eyes with chronic central serous chorioretinopathy using Enhanced Depth Imaging Optical Coherence Tomography (EDI OCT) and Optical Coherence Tomography Angiography (OCT-A). Methods: This prospective case-control study included 10 eyes. Choroid was examined before and at 1 month following hd-vPDT. We measured choroidal thickness (CT) at subfoveal area and at 750 \u03bcm nasal and temporal of fovea and thickness of Haller and choriocapillaris\/Sattler layers. Whole (WA), luminal (LA) and interstitial area (IA) at EDI-OCT, and perfusion density at OCT-A were analyzed. The unaffected fellow eyes were used for comparisons. Results: Mean CT at subfoveal area and at 750 \u03bcm nasal and temporal of fovea, values of Haller and choriocapillaris\/Sattler layers and those of WA, LA and IA were reduced, while PD increased at 1 month after hd-vPDT (all p &lt; 0.001). There was a significant (p &lt; 0.05) negative correlation (\u03c1 = \u22120.658) between PD and post-treatment logMARVA. None of analyzed parameters reached values of unaffected fellow eye. Conclusion: Following hd-vPDT, choroidal thickness with both luminal and interstitial components markedly decreased, while perfusion of choriocapillaris improved.<\/jats:p>","DOI":"10.14712\/18059694.2022.24","type":"journal-article","created":{"date-parts":[[2023,2,3]],"date-time":"2023-02-03T15:48:23Z","timestamp":1675439303000},"page":"89-98","update-policy":"https:\/\/doi.org\/10.14712\/crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["The Choroid after Half-Dose Photodynamic Therapy in Chronic Central Serous Chorioretinopathy"],"prefix":"10.14712","volume":"65","author":[{"given":"Evita Evangelia","family":"Christou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Katsanos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilias","family":"Georgalas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vassilios","family":"Kozobolis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christos","family":"Kalogeropoulos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Stefaniotou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5727","published-online":{"date-parts":[[2023,2,2]]},"reference":[{"key":"18059694.2022.24_1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/S0002-9394(14)70531-8","volume":"121","author":"Pr\u00fcnte","year":"1996","journal-title":"Am J Ophthalmol"},{"key":"18059694.2022.24_2","unstructured":"Katsanos A, Gorgoli K, Konidaris V, Empeslidis T. An overview of risk factors, diagnosis and treatment of central serous chorioretinopathy. In: Patrick Evans (Ed). Central serous chorioretinopathy (CSCR): risk factors, diagnosis and management. Chapter 1, p: 1\u201332. 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