{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T04:47:07Z","timestamp":1790916427370,"version":"4.1.0"},"reference-count":28,"publisher":"Charles University in Prague, Karolinum Press","issue":"1","license":[{"start":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T00:00:00Z","timestamp":1675987200000},"content-version":"vor","delay-in-days":40,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T00:00:00Z","timestamp":1675987200000},"content-version":"tdm","delay-in-days":40,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prague Med. Rep."],"published-print":{"date-parts":[[2023]]},"abstract":"<jats:p>\n                    Odontogenic infections are the most common infectious and inflammatory diseases of the maxillofacial area and problem of the causative pathogen identification is an actual task, part of a permanent process of updating and modernization of treatment and diagnostic protocols and standards. In presented study a purulent exudate from 13 patients with acute purulent odontogenic intraoral lesions was studied by bacteriological method with detection of sensitivity to antibacterial agents. Bacteriological studies showed that genus\n                    <jats:italic>Streptococcus<\/jats:italic>\n                    predominated in 69.23% cases. Pathogenic microorganisms in clinically significant concentrations (10\n                    <jats:sup>5<\/jats:sup>\n                    per 1 ml and above) (\n                    <jats:italic>Streptococcus<\/jats:italic>\n                    and\n                    <jats:italic>Staphylococcus<\/jats:italic>\n                    ) were resistant to Tetracycline and Doxycycline, had moderate sensitivity to macrolides in 22.22% and resistance in 77.78%. Amoxicillin\/clavulanate caused effective growth retardation in 22.22% cases and moderate delay \u2013 in 77.78% without cases of resistance. Sensitivity to cephalosporins was detected in 50.00% cases, moderate sensitivity \u2013 in 38.89%, resistance \u2013 in 11.11%. Fluoroquinolones were the most effective \u2013 sensitivity in 72.22% cases, moderate sensitivity \u2013 in 22.22%, resistance \u2013 in 5.56%. The most effective fluoroquinolones were Moxifloxacin and Ciprofloxacin. The highest resistance to antifungal agents was shown by genus\n                    <jats:italic>Candida<\/jats:italic>\n                    , antifungal susceptibility was observed only in 20.00% cases. The microbiota of purulent odontogenic inflammation in the oral cavity was identified in clinically significant concentrations in only 61.54% cases with predominance of\n                    <jats:italic>Streptococcus<\/jats:italic>\n                    . The most effective antibacterial agents for odontogenic purulent process may be considered among cephalosporins and fluoroquinolones. There is a need to repeat similar studies in other regions of Ukraine and at other times of the year.\n                  <\/jats:p>","DOI":"10.14712\/23362936.2023.2","type":"journal-article","created":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T14:50:19Z","timestamp":1676040619000},"page":"16-32","source":"Crossref","is-referenced-by-count":8,"title":["Identification of Pathogenic Microflora and Its Sensitivity to Antibiotics in Cases of the Odontogenic Purulent Periostitis and Abscesses in the Oral Cavity"],"prefix":"10.14712","volume":"124","author":[{"given":"Iurii","family":"Mochalov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryna","family":"Kryvtsova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrij","family":"Chobey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariya","family":"Kulynych","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5727","published-online":{"date-parts":[[2023,2,10]]},"reference":[{"key":"23362936.2023.2_1","doi-asserted-by":"crossref","first-page":"136","DOI":"10.4103\/0975-5950.183867","volume":"6","author":"Bali","year":"2015","journal-title":"Natl. 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