{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T10:08:16Z","timestamp":1779962896597,"version":"3.53.1"},"reference-count":46,"publisher":"Charles University in Prague, Karolinum Press","issue":"4","license":[{"start":{"date-parts":[[2023,12,9]],"date-time":"2023-12-09T00:00:00Z","timestamp":1702080000000},"content-version":"vor","delay-in-days":342,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,12,9]],"date-time":"2023-12-09T00:00:00Z","timestamp":1702080000000},"content-version":"tdm","delay-in-days":342,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Prague Med. Rep."],"published-print":{"date-parts":[[2023]]},"abstract":"<jats:p>To evaluate the retinal nerve fibre layer (RNFL) thickness and choroidal thickness (CT) in Parkinson disease (PD) patients. A comparative cross-sectional, hospital-based study. 39 PD and 39 controls were recruited, who were gender and age matched. Subjects that fulfilled the inclusion criteria underwent optical coherence tomography for evaluation of RNFL thickness and choroidal thickness (CT). There was significant reduction of RNFL thickness in average (adjusted mean 88.87 \u00b5m vs. 94.82 \u00b5m, P=0.001), superior (adjusted mean 110.08 \u00b5m vs. 119.10 \u00b5m, P=0.002) and temporal (adjusted mean 63.77 \u00b5m vs. 70.36 \u00b5m, P=0.004) in PD compared to controls. The central subfoveal CT was significantly thinner in PD compared to controls (adjusted mean 271.13 \u00b5m vs. 285.10 \u00b5m, P=0.003). In PD group, there was significant weak negative correlation between the duration of PD with average RNFL thickness (r=\u20130.354, P=0.027), moderate negative correlation between the duration of PD with central subfoveal CT (r=\u20130.493, P=0.001), and weak negative correlation between the stage of PD with central subfoveal CT (r=\u20130.380, P=0.017). PD group had significant thinner average, superior and temporal RNFL thickness and CT compared to controls.<\/jats:p>","DOI":"10.14712\/23362936.2023.32","type":"journal-article","created":{"date-parts":[[2023,12,9]],"date-time":"2023-12-09T07:43:10Z","timestamp":1702107790000},"page":"421-434","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of Retinal Nerve Fibre Layer Thickness and Choroidal Thickness in Parkinson Disease Patients"],"prefix":"10.14712","volume":"124","author":[{"given":"Kwang Sheng","family":"Ng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Hudzaifah-Nordin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sathyapriya Tamilarsan","family":"Sarah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wan Hitam","family":"Wan-Hazabbah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abd Halim","family":"Sanihah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5727","published-online":{"date-parts":[[2023,12,9]]},"reference":[{"key":"23362936.2023.32_1","first-page":"e16224","volume":"13","author":"Abd Hamid","year":"2021","journal-title":"Cureus"},{"key":"23362936.2023.32_2","doi-asserted-by":"crossref","first-page":"57","DOI":"10.18071\/isz.74.0057","volume":"74","author":"Atum","year":"2021","journal-title":"Ideggyogy. 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