{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,5]],"date-time":"2024-08-05T09:16:36Z","timestamp":1722849396946},"reference-count":0,"publisher":"CMB Association","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell Mol Biol (Noisy-le-grand)"],"abstract":"<jats:p>A few studies suggested that matrix metalloproteinase 1 (MMP-1) rs1799750 polymorphism was associated with nasopharyngeal carcinoma (NPC) risk. However, other studies did not confirm this result. Thus, we did this meta-analysis to evaluate the association between MMP-1 rs1799750 polymorphism and NPC risk. We searched PubMed and EMBASE. Five studies with 1497 cases and 1643 controls were included in this meta-analysis. Subjects with MMP-1 rs1799750 polymorphism had an decreased NPC risk (OR = 0.79; 95%CI, 0.69\u20130.91; P = 0.0007; I2 = 70%). In the subgroup analysis by smoking, a marginally significant association was found in non-smokers (OR = 0.73, 95% CI 0.52 \u2013 1.04, P = 0.08; I2 = 0%) but not smokers (OR = 0.59, 95% CI 0.24 \u2013 1.42, P = 0.24; I2 = 83%). In conclusion, this meta-analysis showed that MMP-1 rs1799750 polymorphism was significantly associated with NPC risk.<\/jats:p>","DOI":"10.14715\/cmb\/2017.63.10.1","type":"journal-article","created":{"date-parts":[[2017,11,3]],"date-time":"2017-11-03T06:36:54Z","timestamp":1509691014000},"page":"1-3","source":"Crossref","is-referenced-by-count":3,"title":["Matrix metalloproteinase-1 (MMP-1) rs1799750 polymorphism is associated with nasopharyngeal carcinoma (NPC) risk"],"prefix":"10.14715","volume":"63","author":[{"given":"L.","family":"Cao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Dong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"5752","published-online":{"date-parts":[[2017,10,31]]},"container-title":["Cellular and Molecular Biology"],"original-title":[],"link":[{"URL":"https:\/\/cellmolbiol.org\/index.php\/CMB\/article\/download\/1296\/1021","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/cellmolbiol.org\/index.php\/CMB\/article\/download\/1296\/1021","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T15:43:13Z","timestamp":1642520593000},"score":1,"resource":{"primary":{"URL":"https:\/\/cellmolbiol.org\/index.php\/CMB\/article\/view\/1296"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,31]]},"references-count":0,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2017,11,1]]}},"URL":"https:\/\/doi.org\/10.14715\/cmb\/2017.63.10.1","relation":{},"ISSN":["1165-158X","0145-5680"],"issn-type":[{"value":"1165-158X","type":"electronic"},{"value":"0145-5680","type":"print"}],"subject":[],"published":{"date-parts":[[2017,10,31]]}}}