{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T05:07:54Z","timestamp":1792645674517,"version":"4.5.0"},"reference-count":0,"publisher":"CMB Association","issue":"2","license":[{"start":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T00:00:00Z","timestamp":1646006400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cell Mol Biol (Noisy-le-grand)"],"abstract":"<jats:p>Ventilator-associated pneumonia (VAP) is a common nosocomial infection in patients admitted to\nintensive care units (ICU), leading to prolonged stay in the ICU, increased hospital costs, and mortality.\nThis study aimed to compare the effect of using normal saline with eucalyptus in endotracheal\nsuctioning on the rate of ventilator-dependent pneumonia. For this purpose, a randomized clinical trial\nstudy was performed on 120 patients under a ventilator in the hospital ICU. Patients were randomly\ndivided into control and intervention groups. The control group consisted of 60 patients who used 0.9%\nnormal saline to dilute endotracheal secretions. The intervention group also included 60 patients treated\nwith 0.9% normal saline with 5% eucalyptus to dilute endotracheal secretions. The sensitivity of\nisolated microbes was determined by the diffusion susceptibility test Kirby-Bauer disk protocol. The\nCDC protocol was used to diagnose VAP. 100 CFU\/ml of endotracheal aspiration was considered the\ndifferentiation number between the microbe responsible for VAP and colonization. Whenever a VAP\nguess was made, a blood culture was done. Finally, the incidence of ventilator-associated pneumonia in\nthe two groups was compared. The results showed that the incidence of VAP during using normal saline\nand normal saline with eucalyptus as a diluent for pulmonary secretions was different between the two\ngroups (P = 0.042). Also, among infected patients with VAP, there was a difference between the types\nof microorganisms in the two groups (P = 0.019). Seven cases of Klebsiella pneumonia were observed\nin the control group, while no case of this bacterium was observed in the intervention group. In terms of\nthe prevalence of Pseudomonas (two cases), both groups had a similar situation. These findings can\nreassure nurses and the treatment team that they can use normal saline solution with 5% eucalyptus\nduring suction to dilute pulmonary secretions.<\/jats:p>","DOI":"10.14715\/cmb\/2022.68.2.28","type":"journal-article","created":{"date-parts":[[2022,7,30]],"date-time":"2022-07-30T17:56:21Z","timestamp":1659203781000},"page":"197-202","source":"Crossref","is-referenced-by-count":4,"title":["The effect of different solutions in tracheal suctioning on the incidence of pneumonia\nin patients on the ventilator"],"prefix":"10.14715","volume":"68","author":[{"family":"Chunyan  Chai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Xiangzeng Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Yuan  Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5752","published-online":{"date-parts":[[2022,2,28]]},"container-title":["Cellular and Molecular Biology"],"original-title":[],"link":[{"URL":"https:\/\/www.cellmolbiol.org\/index.php\/CMB\/article\/download\/4291\/2065","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.cellmolbiol.org\/index.php\/CMB\/article\/download\/4291\/2065","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,30]],"date-time":"2022-07-30T17:56:30Z","timestamp":1659203790000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cellmolbiol.org\/index.php\/CMB\/article\/view\/4291"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,28]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2022,6,8]]}},"URL":"https:\/\/doi.org\/10.14715\/cmb\/2022.68.2.28","relation":{},"ISSN":["1165-158X","0145-5680"],"issn-type":[{"value":"1165-158X","type":"electronic"},{"value":"0145-5680","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2,28]]}}}