{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T22:00:11Z","timestamp":1770156011220,"version":"3.49.0"},"reference-count":0,"publisher":"Caleo","issue":"3","license":[{"start":{"date-parts":[[2020,11,30]],"date-time":"2020-11-30T00:00:00Z","timestamp":1606694400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Endod J."],"abstract":"<jats:p>Objective: The purpose of this randomized, double-blind study was to evaluate the anesthetic efficacy of lidocaine-ketorolac administration by Inferior Alveolar Nerve Block (IANB) in patients with irreversible pulpitis.Methods: Eighty-eight adult patients received a combination of either one cartridge of \u201c2% lidocaine with 1: 80.000 epinephrine\u201d (Li) plus one cartridge of a mixture of 0.8 mL of the same solution and 1mL ketorolac tromethamine (KT)(30 mg\/mL), or one cartridge of Li solution plus one cartridge of a mixture of the same solution and saline. Endodontic access was prepared after fifteen minutes. Anesthetic success was defined as no or mild pain [less than 54 mm on the Heft-Parker visual analog scale (HP-VAS)] during access cavity preparation and initial file insertion. Chi-square test was used for data analysis, and the level of significance was set at 0.05 (P=0.05).Results: Results showed that the success rates were 34.1% and 27.3% for Li-KT and Li-Saline groups, respectively, with no significant difference between the two groups (P=0.48). However, significant decrease of baseline mean VAS pain score of the participants in both groups was found during access cavity preparation or initial file insertion (P<\/jats:p>","DOI":"10.14744\/eej.2020.74946","type":"journal-article","created":{"date-parts":[[2020,2,5]],"date-time":"2020-02-05T04:43:22Z","timestamp":1580877802000},"page":"186-190","source":"Crossref","is-referenced-by-count":1,"title":["Anesthetic Efficacy of Lidocaine\/Ketorolac in Inferior Alveolar Nerve Block in Patients with Irreversible Pulpitis: A Randomized Clinical Trial"],"prefix":"10.65717","volume":"5","author":[{"given":"Hessamoddin","family":"Faghihian","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reyhaneh","family":"Faghihian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abbasali","family":"Khademi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivek","family":"Aggarwal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"55248","published-online":{"date-parts":[[2020,11,30]]},"container-title":["European Endodontic Journal"],"original-title":[],"link":[{"URL":"https:\/\/www.eurendodj.com\/index.php\/pub\/article\/download\/137\/137","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurendodj.com\/index.php\/pub\/article\/download\/137\/137","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T12:32:15Z","timestamp":1769085135000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eurendodj.com\/index.php\/pub\/article\/view\/137"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,30]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2020,11,30]]}},"URL":"https:\/\/doi.org\/10.14744\/eej.2020.74946","relation":{},"ISSN":["2548-0839"],"issn-type":[{"value":"2548-0839","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,30]]}}}