{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T04:00:29Z","timestamp":1769140829180,"version":"3.49.0"},"reference-count":0,"publisher":"Caleo","issue":"2","license":[{"start":{"date-parts":[[2023,3,17]],"date-time":"2023-03-17T00:00:00Z","timestamp":1679011200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Endod J."],"abstract":"<jats:p>Objective: The management of postoperative endodontic pain (PEP) is essential to contemporary endodontic practice. Diclofenac and ibuprofen (IBU) are two of the most widely-used non-steroidal anti-inflammatory analgesics. However, their comparative data are neither sufficient nor conclusive. This prospective randomised clinical trial aimed to compare the analgesic efficacy of diclofenac potassium (DFK) with IBU on PEP in maxillary and mandibular first molars diagnosed with irreversible pulpitis after single-visit non-surgical root canal treatment.Methods: Sixty-four patients were randomised into two groups of DFK (n=32) and IBU (n=32), using the stratified permuted randomisation method, and 61 participants completed the trial. After root canal treatment, patients randomly received IBU 400 mg every 6 hours (n=31) or DFK 50 mg every 8 hours (n=30) for 24 hours. Patients recorded their pain level on 0-100 mm visual analogue scales (VAS) at 2, 4, 6, 12, and 24 hours after the treatment. Recorded VAS scores and the number of pain-free patients (VAS<\/jats:p>","DOI":"10.14744\/eej.2022.45238","type":"journal-article","created":{"date-parts":[[2022,8,22]],"date-time":"2022-08-22T07:46:20Z","timestamp":1661154380000},"page":"133-139","source":"Crossref","is-referenced-by-count":2,"title":["Analgesic Efficacy of Ibuprofen and Diclofenac Potassium on Postoperative Endodontic Pain in Maxillary and Mandibular First Molars with Irreversible Pulpitis: A Randomised Controlled Trial"],"prefix":"10.65717","volume":"8","author":[{"given":"Mohammadreza","family":"Vatankhah","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nazanin","family":"Zargar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mandana","family":"Naseri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saba","family":"Salem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alireza Akbarzadeh","family":"Baghban","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayeh","family":"Etemadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omid","family":"Dianat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"55248","published-online":{"date-parts":[[2023,3,17]]},"container-title":["European Endodontic Journal"],"original-title":[],"link":[{"URL":"https:\/\/www.eurendodj.com\/index.php\/pub\/article\/download\/237\/237","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurendodj.com\/index.php\/pub\/article\/download\/237\/237","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T12:25:12Z","timestamp":1769084712000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eurendodj.com\/index.php\/pub\/article\/view\/237"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,17]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,3,17]]}},"URL":"https:\/\/doi.org\/10.14744\/eej.2022.45238","relation":{},"ISSN":["2548-0839"],"issn-type":[{"value":"2548-0839","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,17]]}}}