{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T08:06:14Z","timestamp":1790755574141,"version":"4.1.0"},"reference-count":0,"publisher":"Caleo","issue":"2","license":[{"start":{"date-parts":[[2023,3,17]],"date-time":"2023-03-17T00:00:00Z","timestamp":1679011200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Endod J."],"abstract":"<jats:p>Objective: Mitochondrial dynamics play a pivotal role in maintaining the homeostasis of the dental pulp. Inflammation and oxidative stress can trigger changes in mitochondrial dynamics, leading to cell death in the dental pulp. This study aimed to investigate inflammation, oxidative stress, mitochondrial dynamic alterations, and cell death in inflamed pulpal tissues compared to healthy pulp tissues.Methods: Pulpal tissues were collected (n=15 per group) from: 1) healthy people as the control and 2) people with clinically diagnosed irreversible pulpitis. Proteins indicating inflammation, oxidative stress, mitochondrial dynamics, and cell death markers were investigated by western blot analysis. A Student\u2019s t-test was used to analyse differences between the healthy and irreversible pulpitis groups. A probability of 0.05 was used to indicate statistical significance (p<\/jats:p>","DOI":"10.14744\/eej.2022.74745","type":"journal-article","created":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T04:36:29Z","timestamp":1667363789000},"page":"148-155","source":"Crossref","is-referenced-by-count":16,"title":["Observation of Inflammation, Oxidative Stress, Mitochondrial Dynamics, and Apoptosis in Dental Pulp following a Diagnosis of Irreversible Pulpitis"],"prefix":"10.65717","volume":"8","author":[{"given":"Savitri","family":"Vaseenon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khunakorn","family":"Weekate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanida","family":"Srisuwan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nipon","family":"Chattipakorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siriporn","family":"Chattipakorn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"55248","published-online":{"date-parts":[[2023,3,17]]},"container-title":["European Endodontic Journal"],"original-title":[],"link":[{"URL":"https:\/\/www.eurendodj.com\/index.php\/pub\/article\/download\/235\/235","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurendodj.com\/index.php\/pub\/article\/download\/235\/235","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T12:25:14Z","timestamp":1769084714000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eurendodj.com\/index.php\/pub\/article\/view\/235"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,17]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023,3,17]]}},"URL":"https:\/\/doi.org\/10.14744\/eej.2022.74745","relation":{},"ISSN":["2548-0839"],"issn-type":[{"value":"2548-0839","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,17]]}}}