{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T04:45:32Z","timestamp":1769143532009,"version":"3.49.0"},"reference-count":0,"publisher":"Caleo","issue":"3","license":[{"start":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T00:00:00Z","timestamp":1744070400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Endod J."],"abstract":"<jats:p>Objective: This case-control study aimed to explore the expression of different osteogenic-related genes in inflamed dental pulp and to correlate these expressions amongst each other and with the extent of pain.Methods: Dental pulp tissues were collected from patients who were diagnosed with irreversible pulpitis. All samples were processed for RNA extraction and analysis of bone morphogenic protein 2 (BMP2), RUNX family transcription factor 2 (RUNX2), dentine sialophosphoprotein (DSPP), dentine matrix acidic phosphoprotein 1 (DMP1), bone gamma-carboxyglutamate protein (BGLAP), and alkaline phosphatase, biomineralization associated (ALPL) gene expression using real-time PCR. Pearson's correlation analysis was used to assess the linear relationships between different genes and the extent of pain, where p<\/jats:p>","DOI":"10.14744\/eej.2025.24008","type":"journal-article","created":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T08:32:58Z","timestamp":1747125178000},"page":"198-204","source":"Crossref","is-referenced-by-count":0,"title":["Expression of Osteogenic Genes in Dental Pulp and Their Correlations in Patients with Clinically Diagnosed Irreversible Pulpitis"],"prefix":"10.65717","volume":"10","author":[{"given":"Faisal","family":"Alonaizan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hatem","family":"Abuohashish","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Francis","family":"Borgio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sayed","family":"Abdulazeez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaser","family":"Alqabbani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doaa M.","family":"Aleraky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"55248","published-online":{"date-parts":[[2025,4,8]]},"container-title":["European Endodontic Journal"],"original-title":[],"link":[{"URL":"https:\/\/www.eurendodj.com\/index.php\/pub\/article\/download\/336\/336","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.eurendodj.com\/index.php\/pub\/article\/download\/336\/336","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T12:17:17Z","timestamp":1769084237000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.eurendodj.com\/index.php\/pub\/article\/view\/336"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,8]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,4,8]]}},"URL":"https:\/\/doi.org\/10.14744\/eej.2025.24008","relation":{},"ISSN":["2548-0839"],"issn-type":[{"value":"2548-0839","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,8]]}}}