{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:59:12Z","timestamp":1791223152406,"version":"4.1.0"},"reference-count":0,"publisher":"Kare Publishing","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hepatol Forum"],"abstract":"<jats:p>Swietenia macrophylla seeds (SMS), as a traditional medicine, are widely used against diabetes, hypertension, and malaria. To date, knowledge about the safety of human consumption remains limited. We herein reported two cases of drug-induced liver injury (DILI) caused by SMS. Both the patients had positive antinuclear autoantibodies. Hepatotoxicity of SMS is characterized by elevated alanine amino-transaminase and obvious autoimmune-like hepatitis. Furthermore, the 2nd biopsy at the 3rd year of methylprednisolone treatment showed normal liver tissue, and then methylprednisolone was withdrawn. No recurrence occurred during one-year follow-up after methylprednisolone withdrawal. SMS may increase the risk of liver damage for patients with potential immune disorders, and patients with SMS-related DILI may benefit from methylprednisolone.<\/jats:p>","DOI":"10.14744\/hf.2025.18282","type":"journal-article","created":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T19:03:36Z","timestamp":1779131016000},"page":"163-166","source":"Crossref","is-referenced-by-count":0,"title":["Methylprednisolone for Swietenia macrophylla seeds-induced liver injury: A case report"],"prefix":"10.14744","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5987-1711","authenticated-orcid":false,"given":"Ze-yu","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Changzhou Third People\u2019s Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou, China; Institute of Hepatology, Changzhou Third People\u2019s Hospital, Changzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5360-2978","authenticated-orcid":false,"given":"Xiu-jun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Changzhou Third People\u2019s Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou, China; Institute of Hepatology, Changzhou Third People\u2019s Hospital, Changzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-3462-4742","authenticated-orcid":false,"given":"Xue-cheng","family":"Tong","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Changzhou Third People\u2019s Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou, China; Institute of Hepatology, Changzhou Third People\u2019s Hospital, Changzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5428-0058","authenticated-orcid":false,"given":"Yuan","family":"Xue","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Changzhou Third People\u2019s Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou, China; Institute of Hepatology, Changzhou Third People\u2019s Hospital, Changzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5966","published-online":{"date-parts":[[2026]]},"container-title":["Hepatology Forum"],"original-title":[],"link":[{"URL":"https:\/\/file.paplino.com\/hepatologyforum\/pdfs\/1779128901-en.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/hepatologyforum.org\/storage\/upload\/pdfs\/1779128901-en.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:46:55Z","timestamp":1791222415000},"score":1,"resource":{"primary":{"URL":"https:\/\/hepatologyforum.org\/articles\/HF-18282"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.14744\/hf.2025.18282","relation":{},"ISSN":["1307-5888","2757-7392"],"issn-type":[{"value":"1307-5888","type":"print"},{"value":"2757-7392","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}