{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:59:12Z","timestamp":1791223152326,"version":"4.1.0"},"reference-count":0,"publisher":"Kare Publishing","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hepatol Forum"],"abstract":"<jats:p>Background and Aim:\r\nTo evaluate the diagnostic performance, technical feasibility, and safety of percutaneous endobiliary punch biopsy (PEPB) in patients with suspected malignant biliary strictures, particularly when endoscopic approaches are not feasible.\r\nMaterials and Methods:\r\nThis retrospective, single-center study included 23 patients with radiologically confirmed biliary strictures who underwent PEPB between January 2020 and January 2025. All procedures were conducted under fluoroscopic guidance following percutaneous biliary drainage. Clinical, laboratory, and procedural data were reviewed.\r\nResults:\r\nBiopsy samples were adequate for histopathological analysis in all cases. The technical success rate was 100%. Malignancy was diagnosed in 17 patients (73.9%), while 3 cases were benign and 3 were false negatives later confirmed as malignant. The sensitivity and specificity of PEPB were 86.96% and 100%, respectively. Two minor complications (8.7%)\u2014cholangitis and hematoma\u2014occurred and were managed conservatively.\r\nConclusion:\r\nPEPB is a safe, technically viable, and diagnostically accurate method for tissue sampling in biliary strictures. It offers a valuable alternative when endoscopic biopsy fails or is not feasible.<\/jats:p>","DOI":"10.14744\/hf.2026.06659","type":"journal-article","created":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T19:03:36Z","timestamp":1779131016000},"page":"133-138","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of percutaneous endobiliary punch biopsy in suspected malignant biliary strictures: Five-year experience from a tertiary center"],"prefix":"10.14744","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6905-4494","authenticated-orcid":false,"given":"Ufuk","family":"Avcioglu","sequence":"first","affiliation":[{"name":"Department of Gastroenterology, Ondokuz May\u0131s University, Samsun, Turkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1713-7682","authenticated-orcid":false,"given":"Hakan","family":"Demiroz","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Ondokuz May\u0131s University, Samsun, Turkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1390-1030","authenticated-orcid":false,"given":"Aysegul Idil","family":"Soylu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Ondokuz May\u0131s University, Samsun, Turkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2857-5175","authenticated-orcid":false,"given":"Fatih","family":"Uzunkaya","sequence":"additional","affiliation":[{"name":"Department of Radiology, Ondokuz May\u0131s University, Samsun, Turkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5821-670X","authenticated-orcid":false,"given":"Huseyin","family":"Akkaya","sequence":"additional","affiliation":[{"name":"Department of Radiology, Ondokuz May\u0131s University, Samsun, Turkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9985-1811","authenticated-orcid":false,"given":"Ibrahim","family":"Goren","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Ondokuz May\u0131s University, Samsun, Turkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1075-7499","authenticated-orcid":false,"given":"Talat","family":"Ayyildiz","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Ondokuz May\u0131s University, Samsun, Turkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1351-8832","authenticated-orcid":false,"given":"Muge","family":"Ustaoglu Dede","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Ondokuz May\u0131s University, Samsun, Turkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7026-9353","authenticated-orcid":false,"given":"Ahmet","family":"Bektas","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Ondokuz May\u0131s University, Samsun, Turkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"5966","published-online":{"date-parts":[[2026]]},"container-title":["Hepatology Forum"],"original-title":[],"link":[{"URL":"https:\/\/file.paplino.com\/hepatologyforum\/pdfs\/1779128695-en.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/hepatologyforum.org\/storage\/upload\/pdfs\/1779128695-en.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:46:54Z","timestamp":1791222414000},"score":1,"resource":{"primary":{"URL":"https:\/\/hepatologyforum.org\/articles\/HF-06659"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":0,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.14744\/hf.2026.06659","relation":{},"ISSN":["1307-5888","2757-7392"],"issn-type":[{"value":"1307-5888","type":"print"},{"value":"2757-7392","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]}}}