{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T20:55:52Z","timestamp":1740171352207,"version":"3.37.3"},"reference-count":23,"publisher":"Wiley","issue":"16","license":[{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2017,8,22]],"date-time":"2017-08-22T00:00:00Z","timestamp":1503360000000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 GM078502-04-S"],"award-info":[{"award-number":["R01 GM078502-04-S"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Physiol Rep"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.14814\/phy2.13379","type":"journal-article","created":{"date-parts":[[2017,8,23]],"date-time":"2017-08-23T00:10:18Z","timestamp":1503447018000},"page":"e13379","source":"Crossref","is-referenced-by-count":1,"title":["Evidence for ammonium conductance in a mouse thick ascending limb cell line"],"prefix":"10.14814","volume":"5","author":[{"given":"Soojung","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Physiology; Emory University School of Medicine; Atlanta Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Physiology; Emory University School of Medicine; Atlanta Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun Ming","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Physiology; Emory University School of Medicine; Atlanta Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathy","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Physiology; Emory University School of Medicine; Atlanta Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inyeong","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Physiology; Emory University School of Medicine; Atlanta Georgia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,8,22]]},"reference":[{"key":"10.14814\/phy2.13379-BIB0001|phy213379-cit-0001","doi-asserted-by":"crossref","first-page":"F969","DOI":"10.1152\/ajprenal.00010.2011","article-title":"Cellular and molecular basis of increased ammoniagenesis in potassium deprivation","volume":"301","author":"Abu Hossain","year":"2011","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.14814\/phy2.13379-BIB0002|phy213379-cit-0002","doi-asserted-by":"crossref","first-page":"21962","DOI":"10.1016\/S0021-9258(17)31742-8","article-title":"NH4+ transport pathways in cells of medullary thick ascending limb of rat kidney. NH4+ conductance and K+\/NH4+(H+) antiport","volume":"269","author":"Amlal","year":"1994","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.14814\/phy2.13379-BIB0003|phy213379-cit-0003","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1172\/JCI686","article-title":"Potassium depletion downregulates chloride-absorbing transporters in rat kidney","volume":"101","author":"Amlal","year":"1998","journal-title":"J. Clin. Invest."},{"key":"10.14814\/phy2.13379-BIB0004|phy213379-cit-0004","doi-asserted-by":"crossref","first-page":"F1","DOI":"10.1152\/ajprenal.2001.280.1.F1","article-title":"Ammonium carriers in medullary thick ascending limb","volume":"280","author":"Attmane-Elakeb","year":"2001","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.14814\/phy2.13379-BIB0005|phy213379-cit-0005","doi-asserted-by":"crossref","first-page":"C131","DOI":"10.1152\/ajpcell.1982.242.3.C131","article-title":"Amiloride: a molecular probe of sodium transport in tissues and cells","volume":"242","author":"Benos","year":"1982","journal-title":"Am. J. Physiol."},{"key":"10.14814\/phy2.13379-BIB0006|phy213379-cit-0006","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1172\/JCI36581","article-title":"NHE4 is critical for the renal handling of ammonia in rodents","volume":"120","author":"Bourgeois","year":"2010","journal-title":"J. Clin. Invest."},{"key":"10.14814\/phy2.13379-BIB0007|phy213379-cit-0007","first-page":"F366","article-title":"Immunocytochemical localization of Na+ channels in rat kidney medulla","volume":"256","author":"Brown","year":"1989","journal-title":"Am. J. Physiol."},{"key":"10.14814\/phy2.13379-BIB0008|phy213379-cit-0008","first-page":"F35","article-title":"Ammonia and bicarbonate transport by thick ascending limb of rat kidney","volume":"247","author":"Good","year":"1984","journal-title":"Am. J. Physiol."},{"key":"10.14814\/phy2.13379-BIB0009|phy213379-cit-0009","first-page":"808","article-title":"[3H]bumetanide binding to a mouse medullary thick limb (MTAL) cell line (Abstract)","volume":"3","author":"Haas","year":"1992","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.14814\/phy2.13379-BIB0010|phy213379-cit-0010","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.2215\/CJN.07400715","article-title":"Acid-base homeostasis","volume":"10","author":"Hamm","year":"2015","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"10.14814\/phy2.13379-BIB0011|phy213379-cit-0011","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/BF00374462","article-title":"Effects of ammonium chloride on membrane currents of acinar cells dispersed from the rat parotid gland","volume":"420","author":"Hayashi","year":"1992","journal-title":"Pflugers Arch."},{"key":"10.14814\/phy2.13379-BIB0012|phy213379-cit-0012","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1038\/ki.1982.36","article-title":"Systemic and renal acid-base effects of chronic dietary potassium depletion in humans","volume":"21","author":"Jones","year":"1982","journal-title":"Kidney Int."},{"key":"10.14814\/phy2.13379-BIB0013|phy213379-cit-0013","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/BF01869723","article-title":"Ammonium transport in medullary thick ascending limb of rabbit kidney: involvement of the Na+, K+, Cl-cotransporter","volume":"94","author":"Kinne","year":"1986","journal-title":"J. Membr. Biol."},{"key":"10.14814\/phy2.13379-BIB0014|phy213379-cit-0014","doi-asserted-by":"crossref","first-page":"F614","DOI":"10.1152\/ajprenal.1999.276.4.F614","article-title":"Nitric oxide inhibits transcription of the Na+-K+-ATPase \u03b11-subunit gene in an MTAL cell line","volume":"276","author":"Kone","year":"1999","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.14814\/phy2.13379-BIB0015|phy213379-cit-0015","first-page":"F718","article-title":"Role of NF-kappa B in the regulation of inducible nitric oxide synthase in an MTAL cell line","volume":"269","author":"Kone","year":"1995","journal-title":"Am. J. Physiol."},{"key":"10.14814\/phy2.13379-BIB0016|phy213379-cit-0016","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1113\/expphysiol.2011.057844","article-title":"Sodium-bicarbonate cotransporter NBCn1\/Slc4a7 inhibits NH4Cl-mediated inward current in Xenopus oocytes","volume":"96","author":"Lee","year":"2011","journal-title":"Exp. Physiol."},{"key":"10.14814\/phy2.13379-BIB0017|phy213379-cit-0017","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1113\/expphysiol.2010.053967","article-title":"Sodium-bicarbonate cotransporter NBCn1 in the kidney medullary thick ascending limb cell line is upregulated under acidic conditions and enhances ammonium transport","volume":"95","author":"Lee","year":"2010","journal-title":"Exp. Physiol."},{"key":"10.14814\/phy2.13379-BIB0018|phy213379-cit-0018","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.2215\/CJN.04480413","article-title":"Thick ascending limb of the loop of Henle","volume":"9","author":"Mount","year":"2014","journal-title":"Clin. J. Am. Soc. Nephrol."},{"key":"10.14814\/phy2.13379-BIB0019|phy213379-cit-0019","doi-asserted-by":"crossref","first-page":"F493","DOI":"10.1152\/ajprenal.2001.281.3.F493","article-title":"Ammonium interaction with the epithelial sodium channel","volume":"281","author":"Nakhoul","year":"2001","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.14814\/phy2.13379-BIB0020|phy213379-cit-0020","doi-asserted-by":"crossref","first-page":"C1386","DOI":"10.1152\/ajpcell.00211.2010","article-title":"pH sensitivity of ammonium transport by Rhbg","volume":"299","author":"Nakhoul","year":"2010","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.14814\/phy2.13379-BIB0021|phy213379-cit-0021","doi-asserted-by":"crossref","first-page":"11376","DOI":"10.1073\/pnas.0600768103","article-title":"Acid-sensitive ionic channels in midbrain dopamine neurons are sensitive to ammonium, which may contribute to hyperammonemia damage","volume":"103","author":"Pidoplichko","year":"2006","journal-title":"Proc. Natl Acad. Sci. USA"},{"key":"10.14814\/phy2.13379-BIB0022|phy213379-cit-0022","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1002\/cphy.c120010","article-title":"Renal ammonia metabolism and transport","volume":"3","author":"Weiner","year":"2013","journal-title":"Compr. Physiol."},{"key":"10.14814\/phy2.13379-BIB0023|phy213379-cit-0023","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.tins.2006.06.014","article-title":"Acid-sensing ion channels: advances, questions and therapeutic opportunities","volume":"29","author":"Wemmie","year":"2006","journal-title":"Trends Neurosci."}],"container-title":["Physiological Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.14814%2Fphy2.13379","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.14814\/phy2.13379\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T16:42:09Z","timestamp":1659372129000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.14814\/phy2.13379"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8]]},"references-count":23,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2017,8]]}},"URL":"https:\/\/doi.org\/10.14814\/phy2.13379","archive":["Portico"],"relation":{},"ISSN":["2051-817X"],"issn-type":[{"type":"print","value":"2051-817X"}],"subject":[],"published":{"date-parts":[[2017,8]]}}}