{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T12:56:22Z","timestamp":1765976182332,"version":"3.37.3"},"reference-count":20,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2018,1,25]],"date-time":"2018-01-25T00:00:00Z","timestamp":1516838400000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["G1000861"],"award-info":[{"award-number":["G1000861"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Physiol Rep"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.14814\/phy2.13508","type":"journal-article","created":{"date-parts":[[2018,1,30]],"date-time":"2018-01-30T10:42:38Z","timestamp":1517308958000},"page":"e13508","source":"Crossref","is-referenced-by-count":8,"title":["Chloride intracellular channel 1 (CLIC1) contributes to modulation of cyclic AMP-activated whole-cell chloride currents in human bronchial epithelial cells"],"prefix":"10.14814","volume":"6","author":[{"given":"Bo","family":"Liu","sequence":"first","affiliation":[{"name":"Division of Respiratory Medicine; The University of Nottingham; Nottingham United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlotte K.","family":"Billington","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine; The University of Nottingham; Nottingham United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda P.","family":"Henry","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine; The University of Nottingham; Nottingham United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sangita K.","family":"Bhaker","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine; The University of Nottingham; Nottingham United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander K.","family":"Kheirallah","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine; The University of Nottingham; Nottingham United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline","family":"Swan","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine; The University of Nottingham; Nottingham United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian P.","family":"Hall","sequence":"additional","affiliation":[{"name":"Division of Respiratory Medicine; The University of Nottingham; Nottingham United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,1,25]]},"reference":[{"key":"10.14814\/phy2.13508-BIB0001|phy213508-cit-0001","doi-asserted-by":"crossref","first-page":"6003","DOI":"10.1073\/pnas.88.14.6003","article-title":"Calcium and cAMP activate different chloride channels in the apical membrane of normal and cystic fibrosis epithelia","volume":"88","author":"Anderson","year":"1991","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.14814\/phy2.13508-BIB0002|phy213508-cit-0002","doi-asserted-by":"crossref","first-page":"2076","DOI":"10.1016\/j.febslet.2010.02.073","article-title":"Chloride intracellular channel 1 (CLIC1): sensor and effector during oxidative stress","volume":"584","author":"Averaimo","year":"2010","journal-title":"FEBS Lett."},{"key":"10.14814\/phy2.13508-BIB0003|phy213508-cit-0003","doi-asserted-by":"crossref","first-page":"4956","DOI":"10.1073\/pnas.87.13.4956","article-title":"Separate Cl- conductances activated by cAMP and Ca2\u00a0+\u00a0 in Cl(-)-secreting epithelial cells","volume":"87","author":"Cliff","year":"1990","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.14814\/phy2.13508-BIB0004|phy213508-cit-0004","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s00232-006-0059-5","article-title":"The CLIC1 chloride channel is regulated by the cystic fibrosis transmembrane conductance regulator when expressed in Xenopus oocytes","volume":"213","author":"Edwards","year":"2006","journal-title":"J. Membr. Biol."},{"key":"10.14814\/phy2.13508-BIB0005|phy213508-cit-0005","doi-asserted-by":"crossref","first-page":"2102","DOI":"10.1016\/j.febslet.2010.01.037","article-title":"Chloride channels of intracellular membranes","volume":"584","author":"Edwards","year":"2010","journal-title":"FEBS Lett."},{"key":"10.14814\/phy2.13508-BIB0006|phy213508-cit-0006","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1136\/thoraxjnl-2015-207588","article-title":"Airway surface liquid homeostasis in cystic fibrosis: pathophysiology and therapeutic targets","volume":"71","author":"Haq","year":"2016","journal-title":"Thorax"},{"key":"10.14814\/phy2.13508-BIB0007|phy213508-cit-0007","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1186\/s12864-017-3628-3","article-title":"Lung function associated gene Integrator Complex subunit 12 regulates protein synthesis pathways","volume":"18","author":"Kheirallah","year":"2017","journal-title":"BMC Genom."},{"key":"10.14814\/phy2.13508-BIB0008|phy213508-cit-0008","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s00424-007-0300-9","article-title":"Inhibitory effect of DIDS, NPPB, and phloretin on intracellular chloride channels","volume":"455","author":"Malekova","year":"2007","journal-title":"Pflugers Arch."},{"key":"10.14814\/phy2.13508-BIB0009|phy213508-cit-0009","first-page":"2015","article-title":"Chloride channels in cancer: focus on chloride intracellular channel 1 and 4 (CLIC1 AND CLIC4) proteins in tumor development and as novel therapeutic targets","volume":"2523-2531","author":"Peretti","year":"1848","journal-title":"Biochim. Biophys. Acta"},{"key":"10.14814\/phy2.13508-BIB0010|phy213508-cit-0010","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/dvg.20616","article-title":"Generation and characterization of mice with null mutation of the chloride intracellular channel 1 gene","volume":"48","author":"Qiu","year":"2010","journal-title":"Genesis"},{"key":"10.14814\/phy2.13508-BIB0011|phy213508-cit-0011","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1242\/bio.018119","article-title":"CLIC1 regulates dendritic cell antigen processing and presentation by modulating phagosome acidification and proteolysis","volume":"5","author":"Salao","year":"2016","journal-title":"Biol. Open"},{"key":"10.14814\/phy2.13508-BIB0012|phy213508-cit-0012","doi-asserted-by":"crossref","first-page":"C1464","DOI":"10.1152\/ajpcell.1994.266.5.C1464","article-title":"Both CFTR and outwardly rectifying chloride channels contribute to cAMP-stimulated whole cell chloride currents","volume":"266","author":"Schwiebert","year":"1994","journal-title":"Am. J. Physiol."},{"key":"10.14814\/phy2.13508-BIB0013|phy213508-cit-0013","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/S0092-8674(05)80011-X","article-title":"CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP","volume":"81","author":"Schwiebert","year":"1995","journal-title":"Cell"},{"key":"10.14814\/phy2.13508-BIB0014|phy213508-cit-0014","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1165\/rcmb.2003-0109OC","article-title":"The role of the basolateral outwardly rectifying chloride channel in human airway epithelial anion secretion","volume":"29","author":"Szkotak","year":"2003","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.14814\/phy2.13508-BIB0015|phy213508-cit-0015","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1096\/fasebj.14.9.1171","article-title":"Functional characterization of the NCC27 nuclear protein in stable transfected CHO-K1 cells","volume":"14","author":"Tonini","year":"2000","journal-title":"FASEB J."},{"key":"10.14814\/phy2.13508-BIB0016|phy213508-cit-0016","doi-asserted-by":"crossref","first-page":"C1103","DOI":"10.1152\/ajpcell.00402.2001","article-title":"CLIC1 inserts from the aqueous phase into phospholipid membranes, where it functions as an anion channel","volume":"282","author":"Tulk","year":"2002","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.14814\/phy2.13508-BIB0017|phy213508-cit-0017","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1471-2121-8-8","article-title":"Tissue and subcellular distribution of CLIC1","volume":"8","author":"Ulmasov","year":"2007","journal-title":"BMC Cell Biol."},{"key":"10.14814\/phy2.13508-BIB0018|phy213508-cit-0018","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1007\/s10875-006-9029-z","article-title":"Glucocorticoids increase repair potential in a novel in\u00a0vitro human airway epithelial wounding model","volume":"26","author":"Wadsworth","year":"2006","journal-title":"J. Clin. Immunol."},{"key":"10.14814\/phy2.13508-BIB0019|phy213508-cit-0019","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/j.cell.2006.09.043","article-title":"Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis","volume":"127","author":"Wang","year":"2006","journal-title":"Cell"},{"key":"10.14814\/phy2.13508-BIB0020|phy213508-cit-0020","doi-asserted-by":"crossref","first-page":"26003","DOI":"10.1074\/jbc.M203666200","article-title":"Recombinant CLIC1 (NCC27) assembles in lipid bilayers via a pH-dependent two-state process to form chloride ion channels with identical characteristics to those observed in Chinese hamster ovary cells expressing CLIC1","volume":"277","author":"Warton","year":"2002","journal-title":"J. Biol. Chem."}],"container-title":["Physiological Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.14814%2Fphy2.13508","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.14814\/phy2.13508\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,30]],"date-time":"2024-06-30T20:26:27Z","timestamp":1719779187000},"score":1,"resource":{"primary":{"URL":"http:\/\/doi.wiley.com\/10.14814\/phy2.13508"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,1]]}},"URL":"https:\/\/doi.org\/10.14814\/phy2.13508","archive":["Portico"],"relation":{},"ISSN":["2051-817X"],"issn-type":[{"type":"print","value":"2051-817X"}],"subject":[],"published":{"date-parts":[[2018,1]]}}}