{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T01:29:52Z","timestamp":1788398992577,"version":"build-2803163510"},"reference-count":36,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2019,6,26]],"date-time":"2019-06-26T00:00:00Z","timestamp":1561507200000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Physiol Rep"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.14814\/phy2.14153","type":"journal-article","created":{"date-parts":[[2019,6,26]],"date-time":"2019-06-26T23:10:20Z","timestamp":1561590620000},"source":"Crossref","is-referenced-by-count":4,"title":["Population data provide evidence against the presence of a set point for hemoglobin levels or tissue oxygen delivery"],"prefix":"10.14814","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9755-2316","authenticated-orcid":false,"given":"Stephen P.","family":"Fitzgerald","sequence":"first","affiliation":[{"name":"Departments of General Medicine and Endocrinology Royal Adelaide Hospital Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Niels","family":"Grote Beverborg","sequence":"additional","affiliation":[{"name":"Department of Cell and Molecular Biology Karolinska Institutet Stockholm Sweden"},{"name":"Department of Medicine\u2010Cardiology Karolinska Institutet Stockholm Sweden"},{"name":"Department of Cardiology University Medical Center Groningen and Rijksuniversiteit Groningen Groningen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Beguin","sequence":"additional","affiliation":[{"name":"Department of Haematology CHU de Li\u00e8ge and University of Li\u00e8ge Li\u00e8ge Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferruh","family":"Artunc","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Division of Endocrinology, Diabetology, Vascular Disease, Nephrology and Clinical Chemistry University Hospital T\u00fcbingen T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik","family":"Falhammar","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Metabolism and Diabetes Karolinska University Hospital Stockholm Sweden"},{"name":"Department of Molecular Medicine and Surgery Karolinska Institutet Stockholm Sweden"},{"name":"Menzies School of Health Research and Royal Darwin Hospital Tiwi Northern Territory Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigel G.","family":"Bean","sequence":"additional","affiliation":[{"name":"School of Mathematical Sciences and ARC Centre of Excellence for Mathematical and Statistical Frontiers University of Adelaide Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,6,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.87.3.8165"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfm316"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glt154"},{"key":"e_1_2_6_5_1","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1182\/blood.V77.4.868.868","article-title":"Circulating erythropoietin levels after bone marrow transplantation: inappropriate response to anemia in allogenic transplants","volume":"77","author":"Beguin Y.","year":"1991","journal-title":"Blood"},{"key":"e_1_2_6_6_1","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1182\/blood.V81.4.1067.1067","article-title":"Quantitative assessment of erythropoiesis and functional classification of anemia based on measurements of serum transferring receptor and erythropoiesis","volume":"81","author":"Beguin Y.","year":"1993","journal-title":"Blood"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1946.sp004133"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a011619"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.01021.2005"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0753-3322(93)90007-8"},{"key":"e_1_2_6_11_1","first-page":"1267","article-title":"Erythropoietin levels and hematologic parameters in healthy adults","volume":"83","author":"Charuruks N.","year":"2000","journal-title":"J. Med. Assoc."},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2005.53416.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2004.00880.x"},{"key":"e_1_2_6_14_1","first-page":"7","article-title":"The relationship between population T4\/TSH set point data and T4\/TSH physiology","author":"Fitzgerald S. P.","year":"2016","journal-title":"J. Thyr. Res."},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/23328940.2017.1281370"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.14814\/phy2.13551"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/23328940.2018.1513110"},{"key":"e_1_2_6_18_1","article-title":"Walter Cannon: homeostasis, the fight\u2010or flight response, the sympathoadrenal system, and the wisdom of the body","author":"Goldstein D.","year":"2017","journal-title":"Brain Immune Trends"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0125215"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.12034"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2010.195057"},{"key":"e_1_2_6_22_1","first-page":"P69","volume-title":"Cardiovascular physiology concepts","author":"Klabunde R.","year":"2005"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/0167-4943(95)00687-7"},{"key":"e_1_2_6_24_1","unstructured":"Menzel U.2013.EMT: exact multinomial test: goodness\u2010of\u2010fit test for discrete multivariate data https:\/\/CRAN.R-project.org\/package=EMT"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.04690511"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1152\/advan.00107.2015"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000097"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-07-294595"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1515\/jomb-2017-0014"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.13692"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2009.07659.x"},{"key":"e_1_2_6_32_1","volume-title":"R: a language and environment for statistical computing","author":"R Core Team","year":"2017"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00068.2004"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2257.2001.00413.x"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199603073341002"},{"key":"e_1_2_6_36_1","first-page":"40","article-title":"meta: an R package for meta\u2010analysis","volume":"1","author":"Schwarzer G","year":"2007","journal-title":"News"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.008698"}],"container-title":["Physiological Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.14814%2Fphy2.14153","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.14814\/phy2.14153","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.14814\/phy2.14153","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.14814\/phy2.14153","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,11,30]],"date-time":"2019-11-30T18:32:04Z","timestamp":1575138724000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.14814\/phy2.14153"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":36,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2019,6,17]]},"published-print":{"date-parts":[[2019,6]]}},"alternative-id":["10.14814\/phy2.14153"],"URL":"https:\/\/doi.org\/10.14814\/phy2.14153","archive":["Portico"],"relation":{},"ISSN":["2051-817X","2051-817X"],"issn-type":[{"value":"2051-817X","type":"print"},{"value":"2051-817X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6]]}}}