{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,8]],"date-time":"2026-02-08T02:34:27Z","timestamp":1770518067291,"version":"3.49.0"},"reference-count":43,"publisher":"Wiley","issue":"14","license":[{"start":{"date-parts":[[2020,7,20]],"date-time":"2020-07-20T00:00:00Z","timestamp":1595203200000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["DK084538"],"award-info":[{"award-number":["DK084538"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["AA024840"],"award-info":[{"award-number":["AA024840"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Physiol Rep"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.14814\/phy2.14508","type":"journal-article","created":{"date-parts":[[2020,7,20]],"date-time":"2020-07-20T12:01:31Z","timestamp":1595246491000},"source":"Crossref","is-referenced-by-count":13,"title":["Prominin\u20101\u2010expressing hepatic progenitor cells induce fibrogenesis in murine cholestatic liver injury"],"prefix":"10.14814","volume":"8","author":[{"given":"Michael","family":"Fenlon","sequence":"first","affiliation":[{"name":"Developmental Biology, Regenerative Medicine, and Stem Cell Program The Saban Research InstituteChildren\u2019s Hospital of Los Angeles Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celia","family":"Short","sequence":"additional","affiliation":[{"name":"Developmental Biology, Regenerative Medicine, and Stem Cell Program The Saban Research InstituteChildren\u2019s Hospital of Los Angeles Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiabo","family":"Xu","sequence":"additional","affiliation":[{"name":"Developmental Biology, Regenerative Medicine, and Stem Cell Program The Saban Research InstituteChildren\u2019s Hospital of Los Angeles Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Malkoff","sequence":"additional","affiliation":[{"name":"Developmental Biology, Regenerative Medicine, and Stem Cell Program The Saban Research InstituteChildren\u2019s Hospital of Los Angeles Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elaa","family":"Mahdi","sequence":"additional","affiliation":[{"name":"Developmental Biology, Regenerative Medicine, and Stem Cell Program The Saban Research InstituteChildren\u2019s Hospital of Los Angeles Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Hough","sequence":"additional","affiliation":[{"name":"Developmental Biology, Regenerative Medicine, and Stem Cell Program The Saban Research InstituteChildren\u2019s Hospital of Los Angeles Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alison","family":"Glazier","sequence":"additional","affiliation":[{"name":"Developmental Biology, Regenerative Medicine, and Stem Cell Program The Saban Research InstituteChildren\u2019s Hospital of Los Angeles Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Calvin","family":"Lee","sequence":"additional","affiliation":[{"name":"Developmental Biology, Regenerative Medicine, and Stem Cell Program The Saban Research InstituteChildren\u2019s Hospital of Los Angeles Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kinji","family":"Asahina","sequence":"additional","affiliation":[{"name":"Southern California Research Center for ALPD & Cirrhosis Department of Pathology Keck School of Medicine University of Southern California Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0487-6416","authenticated-orcid":false,"given":"Kasper S.","family":"Wang","sequence":"additional","affiliation":[{"name":"Developmental Biology, Regenerative Medicine, and Stem Cell Program The Saban Research InstituteChildren\u2019s Hospital of Los Angeles Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,7,20]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200312172"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.2010.172"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21814"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2667"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-12484-3"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/19420862.2017.1398873"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm6010007"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.08.024"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00452.2016"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1400062111"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI78585"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.15034"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep4.1023"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.3.2006084"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.2012.121"},{"key":"e_1_2_9_17_1","first-page":"846493","article-title":"Hepatocytic Prominin\u20101 protects against liver fibrosis by stabilizing the SMAD7 protein","author":"Lee H.","year":"2019","journal-title":"bioRxiv"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aan8462"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27035"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2016.01.010"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001871"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27203"},{"issue":"4","key":"e_1_2_9_23_1","first-page":"5","article-title":"Decorin deficiency in diabetic mice: Aggravation of nephropathy due to overexpression of profibrotic factors, enhanced apoptosis and mononuclear cell infiltration","volume":"60","author":"Merline R.","year":"2009","journal-title":"Journal of Physiology and Pharmacology"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2014.04.010"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.matbio.2017.12.009"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2016.09.043"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2011.03.008"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2009.090393"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28274"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2019.04.004"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2019.04.005"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27078"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1634\/stemcells.2008-0332"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30150"},{"key":"e_1_2_9_35_1","first-page":"2111","article-title":"CD133 expression is not restricted to stem cells, and both CD133+ and CD133\u2010 metastatic colon cancer cells initiate tumors","volume":"118","author":"Shmelkov S. V.","year":"2008","journal-title":"Journal of Clinical Investigation"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-213X-1-4"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27084"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2014.05.001"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2007.070079"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.02236"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30234"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30550"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.2015.149"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.07.045"}],"container-title":["Physiological Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.14814%2Fphy2.14508","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.14814\/phy2.14508","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.14814\/phy2.14508","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.14814\/phy2.14508","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,31]],"date-time":"2020-07-31T03:51:33Z","timestamp":1596167493000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.14814\/phy2.14508"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":43,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["10.14814\/phy2.14508"],"URL":"https:\/\/doi.org\/10.14814\/phy2.14508","archive":["Portico"],"relation":{},"ISSN":["2051-817X","2051-817X"],"issn-type":[{"value":"2051-817X","type":"print"},{"value":"2051-817X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7]]}}}