{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T18:43:51Z","timestamp":1790534631343,"version":"4.1.0"},"reference-count":17,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T00:00:00Z","timestamp":1619481600000},"content-version":"vor","delay-in-days":26,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["KL2TR003016"],"award-info":[{"award-number":["KL2TR003016"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR003015"],"award-info":[{"award-number":["UL1TR003015"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["F31DK121482"],"award-info":[{"award-number":["F31DK121482"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["R01GM136900"],"award-info":[{"award-number":["R01GM136900"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Physiol Rep"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.14814\/phy2.14843","type":"journal-article","created":{"date-parts":[[2021,4,27]],"date-time":"2021-04-27T15:01:26Z","timestamp":1619535686000},"source":"Crossref","is-referenced-by-count":33,"title":["Reduced adiponectin levels in patients with COVID\u201019 acute respiratory failure: A case\u2010control study"],"prefix":"10.14814","volume":"9","author":[{"given":"Sean M.","family":"Kearns","sequence":"first","affiliation":[{"name":"Department of Medicine University of Virginia School of Medicine Charlottesville VA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katelyn W.","family":"Ahern","sequence":"additional","affiliation":[{"name":"Department of Pharmacology University of Virginia School of Medicine Charlottesville VA USA"},{"name":"Eli Lilly and Company Indianapolis IN USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James T.","family":"Patrie","sequence":"additional","affiliation":[{"name":"Division of Biostatistics Department of Public Health Sciences University of Virginia School of Medicine Charlottesville VA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8081-1214","authenticated-orcid":false,"given":"William B.","family":"Horton","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Virginia School of Medicine Charlottesville VA USA"},{"name":"Division of Endocrinology and Metabolism University of Virginia School of Medicine Charlottesville VA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thurl E.","family":"Harris","sequence":"additional","affiliation":[{"name":"Department of Pharmacology University of Virginia School of Medicine Charlottesville VA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Kadl","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Virginia School of Medicine Charlottesville VA USA"},{"name":"Department of Pharmacology University of Virginia School of Medicine Charlottesville VA USA"},{"name":"Division of Pulmonary and Critical Care Medicine University of Virginia School of Medicine Charlottesville VA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,4,27]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.7326\/M20-3214"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1999.0255"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2020.109776"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-82426-7"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21041219"},{"issue":"2","key":"e_1_2_10_7_1","first-page":"293","article-title":"Tocilizumab modulates serum levels of adiponectin and chemerin in patients with rheumatoid arthritis: potential cardiovascular protective role of IL\u20106 inhibition","volume":"37","author":"Fioravanti A.","year":"2019","journal-title":"Clinical and Experimental Rheumatology"},{"issue":"23","key":"e_1_2_10_8_1","first-page":"2526","article-title":"Acute respiratory distress syndrome: The Berlin Definition","volume":"307","author":"Force A. D. T.","year":"2012","journal-title":"JAMA"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000004553"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.2174\/092986712803833263"},{"key":"e_1_2_10_11_1","unstructured":"Gordon A. C. Mouncey P. R. Al\u2010Beidh F. Rowan K. M. Nichol A. D. Arabi Y. M. Annane D. Beane A. vanBentum\u2010Puijk W. Berry L. R. Bhimani Z. Bonten M. J. M. Bradbury C. A. Brunkhorst F. M. Buzgau A. Cheng A. C. Detry M. A. Duffy E. J. Estcourt L. J. Derde L. P. G.(2021).Interleukin\u20106 receptor antagonists in critically Ill patients with Covid\u201019 \u2013 Preliminary report. medRxiv 2021 2007."},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2020.6252"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1100426"},{"issue":"1","key":"e_1_2_10_14_1","first-page":"33","article-title":"When two pandemics meet: Why Is obesity associated with increased COVID\u201019 mortality?","volume":"1","author":"Lockhart S. M.","year":"2020","journal-title":"Med (N Y)"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2006.01776.x"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.90599.2008"},{"issue":"1","key":"e_1_2_10_17_1","doi-asserted-by":"crossref","first-page":"e000792","DOI":"10.1136\/bmjresp-2020-000792","article-title":"Analyses of abdominal adiposity and metabolic syndrome as risk factors for respiratory distress in COVID\u201019","volume":"7","author":"Zelst C. M.","year":"2020","journal-title":"BMJ Open Respiratory Research"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n84"}],"container-title":["Physiological Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.14814\/phy2.14843","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.14814\/phy2.14843","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.14814\/phy2.14843","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T12:32:05Z","timestamp":1619872325000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.14814\/phy2.14843"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":17,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["10.14814\/phy2.14843"],"URL":"https:\/\/doi.org\/10.14814\/phy2.14843","archive":["Portico"],"relation":{},"ISSN":["2051-817X","2051-817X"],"issn-type":[{"value":"2051-817X","type":"print"},{"value":"2051-817X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4]]}}}