{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T13:56:11Z","timestamp":1762005371437,"version":"3.40.5"},"reference-count":51,"publisher":"Wiley","issue":"21","license":[{"start":{"date-parts":[[2021,11,9]],"date-time":"2021-11-09T00:00:00Z","timestamp":1636416000000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01 HL134828"],"award-info":[{"award-number":["R01 HL134828"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002429","name":"Amgen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002429","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Physiological Reports"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.14814\/phy2.15081","type":"journal-article","created":{"date-parts":[[2021,11,10]],"date-time":"2021-11-10T10:00:31Z","timestamp":1636538431000},"source":"Crossref","is-referenced-by-count":4,"title":["Delayed angiopoietin\u20102 blockade reduces influenza\u2010induced lung injury and improves survival in mice"],"prefix":"10.14814","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6269-8753","authenticated-orcid":false,"given":"Jeffrey E.","family":"Gotts","sequence":"first","affiliation":[{"name":"Departments of Medicine and Anesthesia Cardiovascular Research Institute University of California, San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mazharul","family":"Maishan","sequence":"additional","affiliation":[{"name":"Departments of Medicine and Anesthesia Cardiovascular Research Institute University of California, San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren","family":"Chun","sequence":"additional","affiliation":[{"name":"Departments of Medicine and Anesthesia Cardiovascular Research Institute University of California, San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaohui","family":"Fang","sequence":"additional","affiliation":[{"name":"Departments of Medicine and Anesthesia Cardiovascular Research Institute University of California, San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun\u2010Ya","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Cardiometabolic Disorders Amgen Research Thousand Oaks California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Venice","family":"Chiueh","sequence":"additional","affiliation":[{"name":"Department of Cardiometabolic Disorders Amgen Research Thousand Oaks California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aarif Y.","family":"Khakoo","sequence":"additional","affiliation":[{"name":"Department of Cardiometabolic Disorders Amgen Research Thousand Oaks California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"TaeWeon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Cardiometabolic Disorders Amgen Research Thousand Oaks California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Stolina","sequence":"additional","affiliation":[{"name":"Department of Cardiometabolic Disorders Amgen Research Thousand Oaks California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael A.","family":"Matthay","sequence":"additional","affiliation":[{"name":"Departments of Medicine and Anesthesia Cardiovascular Research Institute University of California, San Francisco San Francisco California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,11,9]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201208-1460OC"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1494"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00459.2010"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2018.05.049"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12621"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)62449-1"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1089\/jir.2010.0078"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2009.090391"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1500244"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.119917"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00178.2005"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/ntr\/ntx062"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00110.2014"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00405.2017"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-017-1851-6"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0033-1351122"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000297955.02633.A4"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g2545"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201307-1338OC"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M700821200"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.21244"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/1753466620905274"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/SHK.0000000000000499"},{"key":"e_1_2_7_25_1","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1165\/rcmb.2013-0148OC","article-title":"Neutrophil\u2010endothelial interactions mediate angiopoietin\u20102\u2010associated pulmonary endothelial cell dysfunction in indirect acute lung injury in mice","volume":"50","author":"Lomas\u2010Neira J.","year":"2014","journal-title":"American Journal of Respiratory Cell and Molecular Biology"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2009-0330OC"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00436-19"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200609-1370OC"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201005-0701OC"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.96432"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00449.2007"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-019-2395-8"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2017.07.007"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2004.09.030"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181eaa5bf"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.4161\/viru.24906"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0030046"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-015-1920-2"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201308-280OC"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-018-5328-0"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa050333"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-021-03499-4"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000000524"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2006-0240OC"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep11030"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a006650"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000001907"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2007.087387"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells10010186"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-016-4352-1"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.659419"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00336.2015"}],"container-title":["Physiological Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.14814\/phy2.15081","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.14814\/phy2.15081","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.14814\/phy2.15081","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,14]],"date-time":"2023-01-14T20:49:38Z","timestamp":1673729378000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.14814\/phy2.15081"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":51,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["10.14814\/phy2.15081"],"URL":"https:\/\/doi.org\/10.14814\/phy2.15081","archive":["Portico"],"relation":{},"ISSN":["2051-817X","2051-817X"],"issn-type":[{"type":"print","value":"2051-817X"},{"type":"electronic","value":"2051-817X"}],"subject":[],"published":{"date-parts":[[2021,11]]}}}