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The cardiac effects of coronary artery disease (CAD) can be quantified using clinical echocardiographic measures, such as ejection fraction (EF). Measures of cardiovascular function typically only used in research settings can provide additional information and maybe more sensitive indices to assess changes after exercise\u2010based cardiac rehabilitation. These additional measures include endothelial function (measured by flow\u2010mediated dilation), left ventricular twist, myocardial performance index, and global longitudinal strain. To investigate the cardiovascular response to 12\u00a0week of either traditional moderate\u2010intensity (TRAD) or stair climbing\u2010based high\u2010intensity interval (STAIR) exercise\u2010based cardiac rehabilitation using both clinical and additional measures of cardiovascular function in individuals with CAD. Measurements were made at baseline (BL) and after supervised (4wk) and unsupervised (12\u00a0week) of training. This study was registered as a clinical trial at clinicaltrials.gov (NCT03235674). Participants were randomized into either TRAD (<jats:italic>n<\/jats:italic>\u00a0=\u00a09, 8M\/1F) and STAIR (<jats:italic>n<\/jats:italic>\u00a0=\u00a09, 8M\/1F). There was a training\u2010associated increase in one component of left ventricular twist: Cardiac apical rotation (TRAD: BL: 5.6\u00a0\u00b1\u00a03.3\u00ba, 4\u00a0week: 8.0\u00a0\u00b1\u00a03.9\u00ba, 12\u00a0week: 6.2\u00a0\u00b1\u00a05.1\u00ba and STAIR: BL: 5.1\u00a0\u00b1\u00a03.6\u00ba, 4\u00a0week: 7.4\u00a0\u00b1\u00a03.9\u00ba, 12\u00a0week: 7.8\u00a0\u00b1\u00a02.8\u00ba, <jats:italic>p<\/jats:italic> (time)\u00a0=\u00a00.03, \u03b7<jats:sup>2<\/jats:sup>\u00a0=\u00a00.20; main effect) and post\u2010hoc analysis revealed a difference between BL and 4\u00a0week (<jats:italic>p\u00a0<\/jats:italic>=\u00a00.02). There were no changes in any other clinical or additional measures of cardiovascular function. The small increase in cardiac apical rotation observed after 4\u00a0weeks of training may indicate an early change in cardiac function. A larger overall training stimulus may be needed to elicit other cardiovascular function changes.<\/jats:p>","DOI":"10.14814\/phy2.15308","type":"journal-article","created":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T06:03:11Z","timestamp":1653026591000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Cardiovascular responses to high\u2010intensity stair climbing in individuals with coronary artery disease"],"prefix":"10.14814","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2280-8505","authenticated-orcid":false,"given":"Sydney E.","family":"Valentino","sequence":"first","affiliation":[{"name":"Department of Kinesiology McMaster University  Hamilton Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily C.","family":"Dunford","sequence":"additional","affiliation":[{"name":"Department of Kinesiology McMaster University  Hamilton Ontario 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