{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T19:03:43Z","timestamp":1790449423595,"version":"4.1.0"},"reference-count":49,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T00:00:00Z","timestamp":1720137600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["K01HL161027"],"award-info":[{"award-number":["K01HL161027"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR002494"],"award-info":[{"award-number":["UL1TR002494"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015326","name":"Common Fund","doi-asserted-by":"publisher","award":["U54AT012307"],"award-info":[{"award-number":["U54AT012307"]}],"id":[{"id":"10.13039\/100015326","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiological Reports"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Post\u2010traumatic stress disorder (PTSD) is associated with increased cardiovascular disease (CVD) risk. Compared with males, females are twice as likely to develop PTSD after trauma exposure, and cardiovascular reactivity to stress is a known risk factor for CVD. We aimed to examine hemodynamic responses to acute mental stress in trauma\u2010exposed females with and without a clinical diagnosis of PTSD. We hypothesized that females with PTSD would have higher heart rate (HR), blood pressure (BP), and lower blood flow velocity (BFV) responsiveness compared with controls. We enrolled 21 females with PTSD and 21 trauma\u2010exposed controls. We continuously measured HR using a three\u2010lead electrocardiogram, BP using finger plethysmography, and brachial BFV using Doppler ultrasound. All variables were recorded during 10\u2009min of supine rest, 5\u2009min of mental arithmetic, and 5\u2009min of recovery. Females with PTSD were older, and had higher BMI and higher resting diastolic BP. Accordingly, age, BMI, and diastolic BP were covariates for all repeated measures analyses. Females with PTSD had a blunted brachial BFV response to mental stress (time\u2009\u00d7\u2009group,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.005) compared with controls, suggesting greater vasoconstriction. HR and BP responses were comparable. In conclusion, our results suggest early impairment of vascular function in premenopausal females with PTSD.\n                  <\/jats:p>","DOI":"10.14814\/phy2.16137","type":"journal-article","created":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T23:13:38Z","timestamp":1720221218000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Blunted brachial blood flow velocity response to acute mental stress in\n                    <scp>PTSD<\/scp>\n                    females"],"prefix":"10.14814","volume":"12","author":[{"given":"Chowdhury Ibtida","family":"Tahmin","sequence":"first","affiliation":[{"name":"Division of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health University of Minnesota Medical School  Minneapolis Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chowdhury Tasnova","family":"Tahsin","sequence":"additional","affiliation":[{"name":"Division of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health University of Minnesota Medical School  Minneapolis Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Redeat","family":"Wattero","sequence":"additional","affiliation":[{"name":"Division of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health University of Minnesota Medical School  Minneapolis Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zynab","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Division of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health University of Minnesota Medical School  Minneapolis Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chasity","family":"Corbin","sequence":"additional","affiliation":[{"name":"Division of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health University of Minnesota Medical School  Minneapolis Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason R.","family":"Carter","sequence":"additional","affiliation":[{"name":"Robbins College of Health and Human Sciences Baylor University  Waco Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanie","family":"Park","sequence":"additional","affiliation":[{"name":"Division of Renal Medicine, Department of Medicine Emory University School of Medicine  Atlanta Georgia USA"},{"name":"Research Service Line, Atlanta VA Health Care System  Decatur Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan B.","family":"Racette","sequence":"additional","affiliation":[{"name":"College of Health Solutions Arizona State University  Phoenix Arizona USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samaah S.","family":"Sullivan","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health The University of Texas Health Science Center\u2010Houston  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael D.","family":"Herr","sequence":"additional","affiliation":[{"name":"Penn State Hershey Medical Center and Penn State College of Medicine Penn State University  State College Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3282-5739","authenticated-orcid":false,"given":"Ida T.","family":"Fonkoue","sequence":"additional","affiliation":[{"name":"Division of Physical Therapy and Rehabilitation Science, Department of Family Medicine and Community Health University of Minnesota Medical School  Minneapolis Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,5]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10286-024-01014-7"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1037\/pas0000254"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0002\u20109149(97)00605\u2010x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2004.079665"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1258\/cvd.2012.012016"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2013.00321"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1994.sp020366"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpsycho.2018.12.003"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(16)30377-7"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00134.2017"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10286\u2010023\u201000995\u20101"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2022.113908"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/prp2.655"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/288373a0"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23063162"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.102.20.2473"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/psyp.14064"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0002\u20108703(00)90083\u20108"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11154405"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00713.2009"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2013.00314"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.cj\u201009\u20100559"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2013.05.029"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/jts.22252"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2019.3252"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00518.2010"},{"key":"e_1_2_10_28_1","unstructured":"Matienzo D. &Bordoni B.(2023).Blood flow [Online].https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32119344"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.778762"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2021.2530"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1080\/20008198.2017.1351204"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033\u20102909.133.2.183"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.103.13.1752"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpsycho.2013.03.019"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13293\u2010018\u20100191\u20109"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2005.089755"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.2174\/1874192401004010302"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2022.02.004"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2006.124313"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00102.2018"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1161\/atvbaha.122.318576"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2009.09.543"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033\u20102909.132.6.959"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.17649"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11123353"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12529\u2010011\u20109190\u20105"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq354"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1161\/cir.0000000000000597"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00684.2019"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.4103\/0253\u20107176.211744"}],"container-title":["Physiological Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.14814\/phy2.16137","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,16]],"date-time":"2024-07-16T05:08:15Z","timestamp":1721106495000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.14814\/phy2.16137"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":49,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.14814\/phy2.16137"],"URL":"https:\/\/doi.org\/10.14814\/phy2.16137","archive":["Portico"],"relation":{},"ISSN":["2051-817X","2051-817X"],"issn-type":[{"value":"2051-817X","type":"print"},{"value":"2051-817X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"2024-06-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e16137"}}