{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T21:09:54Z","timestamp":1790111394531,"version":"4.0.1"},"reference-count":39,"publisher":"Wiley","issue":"15","license":[{"start":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T00:00:00Z","timestamp":1722297600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiological Reports"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    We investigated the effects of neonicotinoid pesticides (NEOs) on the spontaneous swimming and foraging behavior, as well as the morphological and physiological changes of goldfish. Most fish reared in thiamethoxam (THM)\u2010sprayed rice fields showed the scales easily peeled off, and increased ascites. Some individuals showed decreased bio\u2010defense activity and low plasma Ca\n                    <jats:sup>2+<\/jats:sup>\n                    . Similar changes were found in the exposure test to THM (1.0 and 20.0\u2009\u03bcg\/L) and dinotefuran (1.2 and 23.5\u2009\u03bcg\/L). Next, the effects of a low concentration of THM (1.0\u2009\u03bcg\/L) on the spontaneous swimming and foraging behavior of fish were examined. Fish exposed to THM for 1\u2009week became restless and had increased the swimming performance, especially under natural light, white LED lighting and blue LED lighting. Goldfish exposed to THM had also increased intake of shiny white beads under green LED illumination. These results indicate that the exposure to NEO, even for a short period and at low levels, not only suppressed bio\u2010defense activities and metabolic abnormalities, but also stress response, the swimming and foraging behavior of the fish are likely to be significantly suffered.\n                  <\/jats:p>","DOI":"10.14814\/phy2.16138","type":"journal-article","created":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T22:54:50Z","timestamp":1722380090000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Exposure to neonicotinoid pesticides induces physiological disorders and affects color performance and foraging behavior in goldfish"],"prefix":"10.14814","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1428-6463","authenticated-orcid":false,"given":"Izuru","family":"Kakuta","sequence":"first","affiliation":[{"name":"Faculty of Science and Engineering Ishinomaki Senshu Univerisity  Ishinomaki Miyagi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6133-757X","authenticated-orcid":false,"given":"Kiyomi","family":"Takase","sequence":"additional","affiliation":[{"name":"Research Center for Creative Partnerships Ishinomaki Senshu University  Ishinomaki Miyagi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,7,30]]},"reference":[{"issue":"2","key":"e_1_2_9_2_1","first-page":"131","article-title":"Assessment of paddy environment using emergence husks of red\u2010dragonflies with civic participation","volume":"65","author":"Aoda T.","year":"2013","journal-title":"Bulletin Faculty of Agriculture, Niigata University"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1155\/2023\/9951536"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356\u2010020\u201008248\u20108"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22168413"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquatox.2019.105378"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356\u2010021\u201013786\u2010w"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2019.109655"},{"key":"e_1_2_9_9_1","unstructured":"Environmentally Friendly Rice Network. (2006).Cultivation technology text Environmental conservation rice production (ed.by Environmantally Friendly Rice Network Research Committee) pp.1\u201376 (ISBN: 2300100275062)."},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356\u2010020\u201008588\u20105"},{"key":"e_1_2_9_11_1","first-page":"315","volume-title":"The physiology of fishes","author":"Evans D. H.","year":"1993"},{"key":"e_1_2_9_12_1","unstructured":"General Incorporated Association Act beyond trust. (2016).Basic data on domestic use of neonicotinoid chemicals (in Japanese). pp. 1\u201356.https:\/\/www.actbeyondtrust.org\/wp\u2010content\/uploads\/2013\/05\/neonico_basic_data_2016.pdf"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10646\u2010018\u20101979\u20104"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356\u2010014\u20103180\u20105"},{"key":"e_1_2_9_15_1","first-page":"449","volume-title":"Dukes' Physiology of Domestic Animals","author":"Hays V. W.","year":"1985"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2017.10.010"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2017.12.036"},{"key":"e_1_2_9_18_1","first-page":"38","article-title":"Investigation of neonicotinoid insecticides in public water areas","volume":"40","author":"Iwata M.","year":"2022","journal-title":"Annual Report of Miyagi Prefectural Institute of Public Health and Environment"},{"key":"e_1_2_9_19_1","unstructured":"Kakuta I.(2004\u20132020).Survey results of agricultural pesticide concentrations in agricultural waterways and surrounding rivers annual report on pesticide surveys in waters around Japan agricultural cooperatives (JA) Miyagi Tome."},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0032432"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0016\u20106480(83)90147\u20108"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.2c04014"},{"key":"e_1_2_9_23_1","unstructured":"Minister of the Environment Japan. (2016).Agricultural Chemical Registration Standards for Preventing Damage to Animals and Plants in the Living Environment of Water Areas Registration of Agricultural Chemicals Fipronil.https:\/\/www.env.go.jp\/water\/sui\u2010kaitei\/kijun.html"},{"key":"e_1_2_9_24_1","unstructured":"Minister of the Environment Japan. (2017).Agricultural Chemical Registration Standards for Preventing Damage to Animals and Plants in the Living Environment of Water Areas Registration of Agricultural Chemicals Fipronil.https:\/\/www.env.go.jp\/water\/sui\u2010kaitei\/kijun.html"},{"key":"e_1_2_9_25_1","unstructured":"Minister of the Environment Japan Agricultural Chemical Registration Standards for Water Pollution (Documents related to the establishment of standards for withholding pesticide registrations related to water pollution for Thiamethoxam). (2010).https:\/\/www.env.go.jp\/content\/900541216.pdf"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.3147\/JSFP.33.141"},{"key":"e_1_2_9_27_1","volume-title":"Harper's biochemistry","author":"Murray R. K.","year":"2000"},{"key":"e_1_2_9_28_1","unstructured":"Rania A. &Zaidi N.(2023).Growth and nutrient levels of freshwater fish treated with neonicotinoid added to the rearing water.Proceeding 4 Water and Environment 1st International Virtual Seminar on Geosciences. Constantine Algeria. pp. 183\u2010187.https:\/\/www.researchgate.net\/publication\/373328172"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2009.04.021"},{"key":"e_1_2_9_30_1","unstructured":"Sakamoto M. Fujimori Y. Matsubara N. Yasuma H. Shimizu S. &Katakura S.(2017).Fish attracting effects of LED light of different colours.Citation Proceedings of the 13th International Workshop on Methods for the Development and Evaluation of Maritime.Technologies. pp. 2\u20134 2017. Sapporo Japan 235\u2013240.http:\/\/hdl.handle.net\/2115\/72391"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.32211\/lamer.58.1\u20102_1"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2016.05.049"},{"key":"e_1_2_9_33_1","first-page":"8","article-title":"Behavioral changes in Japanese killifish (Oryzias latipes) following exposure to neonicotinoid pesticides","volume":"5","author":"Takase K.","year":"2024","journal-title":"Salt and Seawater Science & Technology"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010021\u201081548\u20102"},{"key":"e_1_2_9_35_1","first-page":"19","article-title":"Selection of suitable light environment for preventing caudal fin defects in seedlings of marbled flounder Pseudopleuronectes yokohamae","volume":"13","author":"Ueki M.","year":"2019","journal-title":"Bull Chiba Pref Fish Res Ctr"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2017.11.176"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2019.03.002"},{"key":"e_1_2_9_38_1","first-page":"1","volume-title":"NTP research report on the scoping review of potential human health effects associated with exposures to neonicotinoid pesticides: Research Report 15","author":"Windy A. B.","year":"2020"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf504895h"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2022.159883"}],"container-title":["Physiological Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.14814\/phy2.16138","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T03:11:21Z","timestamp":1723605081000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.14814\/phy2.16138"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,30]]},"references-count":39,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.14814\/phy2.16138"],"URL":"https:\/\/doi.org\/10.14814\/phy2.16138","archive":["Portico"],"relation":{},"ISSN":["2051-817X","2051-817X"],"issn-type":[{"value":"2051-817X","type":"print"},{"value":"2051-817X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,30]]},"assertion":[{"value":"2023-11-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e16138"}}