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Exercise can contribute to the modulation of GM. This is the first case study to analyze the composition and metabolism of the GM of an obese runner in a single\u2010stage mountain ultramarathon (MUM) with a mileage of 217\u2009km. Fecal samples were collected 7\u2009days before the race (T0), 15\u2009min after the end of the race (T1), and 7\u2009days after the end of the race (T2). GM composition was analyzed by real\u2010time PCR and shotgun sequencing. We observed a decrease in Bacillota\/Bacteroidota ratio and \u03b1\u2010diversity after the race. After the 217\u2010km MUM, we observed a decrease in symbiont microorganisms and a notable increase in harmful bacteria. In conclusion, we found that the 217\u2010km MUM may have contributed to the intestinal dysbiosis of the obese runner.<\/jats:p>","DOI":"10.14814\/phy2.70017","type":"journal-article","created":{"date-parts":[[2024,8,23]],"date-time":"2024-08-23T03:14:01Z","timestamp":1724382841000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Effects of a 217\u2010km mountain ultramarathon on the gut microbiota of an obese runner: A case report"],"prefix":"10.14814","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8240-4644","authenticated-orcid":false,"given":"Giulio Kai","family":"Saragiotto","sequence":"first","affiliation":[{"name":"Faculdade de Ci\u00eancias Aplicadas Universidade Estadual de Campinas (FCA\/UNICAMP)  Limeira S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4535-0621","authenticated-orcid":false,"given":"Luiz Felipe Valter","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Department of Biotechnologies BiomeHub  Florian\u00f3polis Santa Catarina Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4072-6135","authenticated-orcid":false,"given":"Nayara Kastem","family":"Scharlack","sequence":"additional","affiliation":[{"name":"Faculdade de Ci\u00eancias Aplicadas Universidade Estadual de Campinas (FCA\/UNICAMP)  Limeira S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9795-0863","authenticated-orcid":false,"given":"Milena Merizzi","family":"de Oliveira","sequence":"additional","affiliation":[{"name":"Faculdade de Ci\u00eancias Aplicadas Universidade Estadual de Campinas (FCA\/UNICAMP)  Limeira S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3475-4196","authenticated-orcid":false,"given":"Fernanda Campos","family":"Freire","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences, State University of S\u00e3o Paulo \u201cJ\u00falio de Mesquita Filho\u201d (UNESP)  Araraquara S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1672-9686","authenticated-orcid":false,"given":"Fernando Moreira","family":"Simabuco","sequence":"additional","affiliation":[{"name":"Faculdade de Ci\u00eancias Aplicadas Universidade Estadual de Campinas (FCA\/UNICAMP)  Limeira S\u00e3o Paulo Brazil"},{"name":"Departamento de Bioqu\u00edmica Universidade Federal de S\u00e3o Paulo (UNIFESP)  S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8632-1478","authenticated-orcid":false,"given":"Katia","family":"Sivieri","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences, State University of S\u00e3o Paulo \u201cJ\u00falio de Mesquita Filho\u201d (UNESP)  Araraquara S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1763-3715","authenticated-orcid":false,"given":"Adilson","family":"Sartoratto","sequence":"additional","affiliation":[{"name":"Centro Pluridisciplinar de Pesquisas Qu\u00edmicas Biol\u00f3gicas e Agr\u00edcolas, Universidade Estadual de Campinas (CPQBA\/UNICAMP)  Paul\u00ednia S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6755-1099","authenticated-orcid":false,"given":"Taisa","family":"Belli","sequence":"additional","affiliation":[{"name":"Faculdade de Ci\u00eancias Aplicadas Universidade Estadual de Campinas (FCA\/UNICAMP)  Limeira S\u00e3o Paulo Brazil"},{"name":"Departamento de Ci\u00eancias do Esporte Faculdade de Educa\u00e7\u00e3o F\u00edsica, Universidade Estadual de Campinas (FEF\/UNICAMP)  Campinas S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1548-1367","authenticated-orcid":false,"given":"Adriane Elisabete Costa","family":"Antunes","sequence":"additional","affiliation":[{"name":"Faculdade de Ci\u00eancias Aplicadas Universidade Estadual de Campinas (FCA\/UNICAMP)  Limeira S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,22]]},"reference":[{"key":"e_1_2_11_2_1","volume-title":"Klebsiella Pneumonia","author":"Ashurst J. 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