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We investigated macro\u2010 and microvascular function after acute nitrate supplementation in postmenopausal females (PMF). Vascular function was studied with flow\u2010mediated vasodilation (FMD) and near\u2010infrared post occlusive reactive hyperemia (PORH). Incremental handgrip exercise was performed to investigate blood flow and tissue oxygenation. We hypothesized acute dietary nitrate would not impact resting endothelial measures but would increase post ischemic vasodilation and incremental exercise blood flow. Late\u2010phase PMF (<jats:italic>n<\/jats:italic>\u2009=\u200912) participated in a randomized crossover design with 140\u2009mL of nitrate\u2010rich (NR) beetroot juice or nitrate\u2010poor black currant juice. Testing included a 5\u2010min FMD, a 3\u2010min ischemic exercise FMD, and incremental exercise at 10%, 15%, and 20% maximal voluntary contraction to measure blood flow and pressure responses. A <jats:italic>p<\/jats:italic>\u2009\u2264\u20090.05 was considered significant. One\u2010way ANOVA indicated lower resting pressures, but no change to FMD, or PORH in either protocol. Two\u2010way repeated measures ANOVA indicated NR supplementation significantly reduced mean arterial pressure at rest and during incremental exercise at all intensities without changes to blood flow. Acute nitrate is effective for resting and exercising blood pressure management in PMF.<\/jats:p>","DOI":"10.14814\/phy2.70076","type":"journal-article","created":{"date-parts":[[2024,10,5]],"date-time":"2024-10-05T03:55:06Z","timestamp":1728100506000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Acute impact of inorganic nitrate supplementation after ischemia and during small muscle mass exercise in postmenopausal females: A pilot study"],"prefix":"10.14814","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2893-4986","authenticated-orcid":false,"given":"Jacob T.","family":"Caldwell","sequence":"first","affiliation":[{"name":"Exercise and Sport Science Department University of Wisconsin\u2010La Crosse  La Crosse Wisconsin USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alyssa","family":"Koenke","sequence":"additional","affiliation":[{"name":"Exercise and Sport Science 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