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To investigate this, a correlational study was carried out on athlete horses under the same management conditions. Fecal microbiota diversity and composition, fibrolytic efficiency and SCFAs were analyzed. An incremental running test was carried out to estimate the maximal running speed (MRS) of the horses, and blood samples were taken to measure energy metabolism parameters. MRS was positively correlated with the efficiency of the fecal microbiota in degrading cellulose in\u00a0vitro (<jats:italic>r<\/jats:italic>\u2009=\u20090.51; <jats:italic>p<\/jats:italic>\u2009=\u20090.02). The abundance of fibrolytic bacterial taxa was not associated with MRS, but functional inference analysis revealed a positive association between MRS and pathways potentially related to fibrolytic activity (<jats:italic>r<\/jats:italic>\u2009=\u20090.54; <jats:italic>p<\/jats:italic>\u2009=\u20090.07 and <jats:italic>r<\/jats:italic>\u2009=\u20090.56; <jats:italic>p<\/jats:italic>\u2009=\u20090.05 for butyrate metabolism and thiamine metabolism, respectively). In contrast, the metabolic pathway of starch degradation appeared negatively associated with MRS (<jats:italic>r<\/jats:italic>\u2009=\u2009\u22120.55; <jats:italic>p<\/jats:italic>\u2009=\u20090.06). The present findings suggest a potential contribution of the large intestine microbiota and dietary fibers digestion to exercise capacity in equine athletes.<\/jats:p>","DOI":"10.14814\/phy2.70110","type":"journal-article","created":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T12:08:16Z","timestamp":1731499696000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Fibrolytic efficiency of the large intestine microbiota may benefit running speed in French trotters: A pilot study"],"prefix":"10.14814","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-3365-8823","authenticated-orcid":false,"given":"Maximilien","family":"Vasseur","sequence":"first","affiliation":[{"name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale, Inserm UMR 1093, Cognition Action et Plasticit\u00e9 Sensorimotrice (CAPS), Faculty of Sport Sciences Universit\u00e9 de Bourgogne  Dijon France"},{"name":"Lab to 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