{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T05:02:34Z","timestamp":1781326954458,"version":"3.54.1"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T00:00:00Z","timestamp":1741737600000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiological Reports"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Monitoring intraperitoneal pressure (IPP) offers valuable insights into changes of intraperitoneal volume (IPV) during peritoneal dialysis (PD). This study aims to investigate the relationship between IPV and IPP during a PD dwell. Thirteen patients were studied during a 2\u2010h dwell using 2\u2009L of dialysate containing 2.5% dextrose. IPP was measured using a pressure sensor integrated into an automated PD cycler. IPV was monitored concurrently by segmental bioimpedance (Hydra 4200). The density (<jats:italic>\u03c1<\/jats:italic>) of the PD dialysate was measured using a meter, and the creatinine and glucose concentrations in both dialysate (D) and serum (P) were measured pre\u2010 and post\u2010PD dwell. A physical model (IPP\u2009=\u2009<jats:italic>\u03c1<\/jats:italic>\u2009\u00d7\u2009<jats:italic>g<\/jats:italic>\u2009\u00d7\u2009<jats:italic>h<\/jats:italic>), was used to describe the relationship between IPP and IPV, where h is the apparent dialysate height and g is the gravitational acceleration. The change in IPP (\u0394IPP, \u221221.2\u2009\u00b1\u200918%) was mainly determined by the change of h (\u0394h, \u221220.9\u2009\u00b1\u200918.5%), while the change <jats:italic>\u03c1<\/jats:italic> (\u0394<jats:italic>\u03c1<\/jats:italic>, \u22120.34\u2009\u00b1\u20090.06%), was minor. The study demonstrated an association between \u0394IPP and the ratio of D\/P creatinine and D\/D<jats:sub>0<\/jats:sub> glucose, suggesting that \u0394IPP may reflect membrane transport characteristics. Due to its noninvasive and seamless nature, the clinical utility of PD cycler\u2010based measurement of IPP warrants further exploration.<\/jats:p>","DOI":"10.14814\/phy2.70179","type":"journal-article","created":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T11:50:56Z","timestamp":1741780256000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Relationship between intraperitoneal volume and intraperitoneal pressure during peritoneal dialysis\u2014a pilot study in adult patients"],"prefix":"10.14814","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7665-2107","authenticated-orcid":false,"given":"Fansan","family":"Zhu","sequence":"first","affiliation":[{"name":"Renal Research Institute  New York City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura Rosales","family":"Merlo","sequence":"additional","affiliation":[{"name":"Renal Research Institute  New York City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lela","family":"Tisdale","sequence":"additional","affiliation":[{"name":"Renal Research Institute  New York City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maricar","family":"Villarama","sequence":"additional","affiliation":[{"name":"Mount Sinai Hospital  New York City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Yi","sequence":"additional","affiliation":[{"name":"Fresenius Medical Care North America  Waltham Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahin","family":"Haq","sequence":"additional","affiliation":[{"name":"Renal Research Institute  New York City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoling","family":"Wang","sequence":"additional","affiliation":[{"name":"Renal Research Institute  New York City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadja","family":"Grobe","sequence":"additional","affiliation":[{"name":"Renal Research Institute  New York City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karsten","family":"Fischer","sequence":"additional","affiliation":[{"name":"Fresenius Medical Care North America  Waltham Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kulwinder","family":"Plahey","sequence":"additional","affiliation":[{"name":"Fresenius Medical Care North America  Waltham Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard A.","family":"Lasher","sequence":"additional","affiliation":[{"name":"Fresenius Medical Care North America  Waltham Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Chamney","sequence":"additional","affiliation":[{"name":"Fresenius Medical Care AG  Bad Homburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Schiller","sequence":"additional","affiliation":[{"name":"Fresenius Medical Care North America  Waltham Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Kotanko","sequence":"additional","affiliation":[{"name":"Renal Research Institute  New York City New York USA"},{"name":"Icahn School of Medicine at Mount Sinai  New York City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,3,12]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2008.32"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2004060506"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfl745"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2013.250"},{"key":"e_1_2_13_6_1","first-page":"22","article-title":"Intraperitoneal pressure, peritoneal permeability and volume of ultrafiltration in CAPD","volume":"8","author":"Durand P. 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