{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T14:57:15Z","timestamp":1780412235955,"version":"3.54.1"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T00:00:00Z","timestamp":1738800000000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004748","name":"Mashhad University of Medical Sciences","doi-asserted-by":"publisher","award":["961778"],"award-info":[{"award-number":["961778"]}],"id":[{"id":"10.13039\/501100004748","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiological Reports"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Reduced left ventricular (LV) function predicts poor outcomes in end\u2010stage renal disease (ESRD). This study aimed to identify the pre\u2010renal transplantation echocardiographic parameters that can predict post\u2010renal transplantation LV failure. This prospective longitudinal study was conducted on patients with ESRD who underwent renal transplantation during 1\u2009year. All patients underwent echocardiography, including ejection fraction (EF), global longitudinal strain (GLS), left ventricular end\u2010systolic diameter (LVESD), left ventricular end\u2010diastolic volume (LVEDV), left ventricular end\u2010diastolic diameter (LVEDD), interventricular septal (IVS) thickness, peak velocity of early diastolic transmitral flow (E), peak velocity of late transmitral flow (A), early diastolic myocardial relaxation (Em), E\/A, E\/Em, Left atrial volume (LAV) index, tricuspid regurgitation peak gradient (TRPG), systolic pulmonary artery pressure (SPAP), tricuspid annular plane systolic excursion (TAPSE), 1\u2009week before and 1\u2009month after renal transplantation. Fifty patients participated in the current study. All echocardiographic parameters improved after transplantation. Post\u2010renal transplantation LV dysfunction was observed in 21 (42%) patients. Pre\u2010renal transplantation echocardiographic parameters (LVEDV, LVESD, LVEDD, IVS, E\/Em, TRPG, SPAP, and LAV index) could predict post\u2010transplantation LV failure with high accuracy (AUC: 0.978).<\/jats:p>","DOI":"10.14814\/phy2.70198","type":"journal-article","created":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T06:58:46Z","timestamp":1738825126000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Defining the predictors for post renal transplant left ventricular dysfunction in end\u2010stage renal disease patients"],"prefix":"10.14814","volume":"13","author":[{"given":"Mahboobeh","family":"Sheikhani","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Diseases, Faculty of Medicine Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0764-6563","authenticated-orcid":false,"given":"Hoorak","family":"Poorzand","sequence":"additional","affiliation":[{"name":"Cardiovascular Division, Vascular and Endovascular Surgery Research Centre Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahnaz","family":"Ahmadi","sequence":"additional","affiliation":[{"name":"Nephrology Research Center, Montaserieh Hospital Mashhad University of Medical Science  Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4308-1931","authenticated-orcid":false,"given":"Negar","family":"Morovatdar","sequence":"additional","affiliation":[{"name":"Clinical Research Development Unit, Imam Reza Hospital Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Afshar","sequence":"additional","affiliation":[{"name":"Cardiovascular Division, Vascular and Endovascular Surgery Research Centre Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1848-1729","authenticated-orcid":false,"given":"Zahra","family":"Shahinfar","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Diseases, Faculty of Medicine Mashhad University of Medical Sciences  Mashhad Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,6]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2013.243"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2014010108"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/1744-9987.12716"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ckj\/sfaa010"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.15171\/jcvtr.2018.14"},{"issue":"5","key":"e_1_2_12_7_1","first-page":"371","article-title":"Medical management of heart failure with reduced ejection fraction in patients with advanced renal disease. 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