{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T02:44:05Z","timestamp":1790304245845,"version":"4.1.0"},"reference-count":32,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T00:00:00Z","timestamp":1744848000000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001711","name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","doi-asserted-by":"publisher","award":["210839\/225270"],"award-info":[{"award-number":["210839\/225270"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiological Reports"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>\n                    <jats:sc>A<\/jats:sc>\n                    bstract\n                  <\/jats:title>\n                  <jats:p>\n                    Cerebrovascular autoregulation (CAR) maintains stable cerebral perfusion by adjusting arteriole diameters in response to slow pressure fluctuations. Various CAR correlation coefficients\u2014PRx (based on intracranial pressure\u2014ICP), Mx (based on transcranial doppler\u2014TCD), and COx\/THx (based on near\u2010infrared spectroscopy\u2014NIRS)\u2014are used interchangeably despite fundamental differences. 566\u2009hours of ICP, NIRS, and TCD data from 38 traumatic brain injury (TBI) patients were assessed. The intercorrelation between CAR correlation coefficients was compared in relation to: (1) The impact of different filtering methods (to minimize noise); (2) The impact of slow wave power (i.e., magnitude of incoming trigger); (3) The impact of coherence (i.e., to what extent can the power of slow waves explain the change in power within the cerebral biosignal). Only coherence stratification consistently increased the metric intercorrelation to PRx (high vs. low) when evaluating Mx (0.43 vs. 0.08,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.01) and THx (0.36 vs. 0.05,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.01). Additionally, high coherence and ABP power were associated with fewer correlation coefficients around 0. Coherence increases the intercorrelation between the different CAR metrics. These sections might be regarded as more reliable, since they are derived from different biosignals that are all affected by CAR through different mechanisms.\n                  <\/jats:p>","DOI":"10.14814\/phy2.70332","type":"journal-article","created":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T07:25:27Z","timestamp":1744874727000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Untangling discrepancies between cerebrovascular autoregulation correlation coefficients: An exploration of filters, coherence and power"],"prefix":"10.14814","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5386-0811","authenticated-orcid":false,"given":"Stefan Yu","family":"B\u00f6gli","sequence":"first","affiliation":[{"name":"Brain Physics Laboratory, Division of Neurosurgery, Department of Clinical Neurosciences University of Cambridge  Cambridge UK"},{"name":"Department of Neurology and Neurocritical Care Unit, Clinical Neuroscience Center University Hospital Zurich, University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ihsane","family":"Olakorede","sequence":"additional","affiliation":[{"name":"Brain Physics Laboratory, Division of Neurosurgery, Department of Clinical Neurosciences University of Cambridge  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erta","family":"Beqiri","sequence":"additional","affiliation":[{"name":"Brain Physics Laboratory, Division of Neurosurgery, Department of Clinical Neurosciences University of Cambridge  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giada","family":"Cucciolini","sequence":"additional","affiliation":[{"name":"Brain Physics Laboratory, Division of Neurosurgery, Department of Clinical Neurosciences University of Cambridge  Cambridge UK"},{"name":"Department of Surgical, Medical, Molecular Pathology and Critical Care Medicine University of Pisa  Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia","family":"Motroni","sequence":"additional","affiliation":[{"name":"Brain Physics Laboratory, Division of Neurosurgery, Department of Clinical Neurosciences University of Cambridge  Cambridge UK"},{"name":"Department of Surgical, Medical, Molecular Pathology and Critical Care Medicine University of Pisa  Pisa Italy"},{"name":"Departmental Structure of Neuroanesthesia and Critical Care Azienda Ospedaliero\u2010Universitaria Pisana  Pisa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia Ann","family":"Smith","sequence":"additional","affiliation":[{"name":"Brain Physics Laboratory, Division of Neurosurgery, Department of Clinical Neurosciences University of Cambridge  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina Sandra","family":"Cherchi","sequence":"additional","affiliation":[{"name":"Brain Physics Laboratory, Division of Neurosurgery, Department of Clinical Neurosciences University of Cambridge  Cambridge UK"},{"name":"Department of Critical Care Marques de Valdecilla University Hospital, and Biomedical Research Institute (IDIVAL)  Santander Cantabria Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronan","family":"O'Leary","sequence":"additional","affiliation":[{"name":"Neurosciences and Trauma Critical Care Unit Addenbrooke's Hospital, Cambridge University Hospitals  Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Smielewski","sequence":"additional","affiliation":[{"name":"Brain Physics Laboratory, Division of Neurosurgery, Department of Clinical Neurosciences University of Cambridge  Cambridge 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the \u201cprobable error\u201d of a coefficient of correlation deduced from a small sample","volume":"1","author":"Fisher R. 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