{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T01:58:44Z","timestamp":1755223124667,"version":"3.43.0"},"reference-count":29,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2018\/21600\u20100"],"award-info":[{"award-number":["2018\/21600\u20100"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["Finance Code 001\u2010 CAPES\/PROEX"],"award-info":[{"award-number":["Finance Code 001\u2010 CAPES\/PROEX"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiological Reports"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Exposure to air pollution has been a significant challenge in large cities as S\u00e3o Paulo, Brazil, particularly for individuals exercising outdoors. The increasing on ventilation (VE) during physical effort can lead to greater pollutant inhalation. Our goal in the present study evaluated whether air pollution exposure affects venous blood gases and if it has an impact on performance during a 50\u2010km cycling time trial (TT). Ten male cyclists performed the TT in an environmental chamber under TRAP and filtered air conditions. Venous blood samples collected pre\u2010 and post\u2010TT were analyzed for pH, PvCO<jats:sub>2<\/jats:sub> (partial pressure of carbon dioxide in venous blood), PvO<jats:sub>2<\/jats:sub> (partial pressure of oxygen in venous blood) hematocrit (Htc), hemoglobin (Hb), and oxygen saturation (SvO<jats:sub>2<\/jats:sub>). PM<jats:sub>2.5<\/jats:sub> levels were significantly lower in filtered air (11.2\u2009\u00b1\u20094.7\u2009\u03bcm\/m<jats:sup>3<\/jats:sup>) than in TRAP (34.6\u2009\u00b1\u200910.8\u2009\u03bcm\/m<jats:sup>3<\/jats:sup>). There was no significant difference in mean power output between conditions (<jats:italic>p<\/jats:italic>\u2009=\u20090.907, <jats:italic>d<\/jats:italic>\u2009=\u20090.038). Blood gas parameters showed no condition effect or interaction, but time significantly affected PvO<jats:sub>2<\/jats:sub> (<jats:italic>p<\/jats:italic>\u2009=\u20090.04), Hb (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01), Htc (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01), and PvCO<jats:sub>2<\/jats:sub> (<jats:italic>p<\/jats:italic>\u2009=\u20090.02). These findings suggest recreationally trained cyclists experience no performance impairment under TRAP, with minimal changes in venous blood gas parameters.<\/jats:p>","DOI":"10.14814\/phy2.70408","type":"journal-article","created":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T22:50:28Z","timestamp":1748818228000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Does traffic\u2010related air pollution exposure alter blood gas parameters in recreationally trained male cyclists during prolonged endurance exercise?"],"prefix":"10.14814","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2549-5452","authenticated-orcid":false,"given":"Andr\u00e9 C.","family":"Silveira","sequence":"first","affiliation":[{"name":"Endurance Performance Research Group (GEDAE\u2010USP), School of Physical Education and Sport University of S\u00e3o Paulo  S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00falio S.","family":"Hasegawa","sequence":"additional","affiliation":[{"name":"Endurance Performance Research Group (GEDAE\u2010USP), School of Physical Education and Sport University of S\u00e3o Paulo  S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramon","family":"Cruz","sequence":"additional","affiliation":[{"name":"Endurance Performance Research Group (GEDAE\u2010USP), School of Physical Education and Sport University of S\u00e3o Paulo  S\u00e3o Paulo S\u00e3o Paulo Brazil"},{"name":"Unit of Environmental Condition and Endurance Performance Analysis (UACAMDA), Sports Center, Department of Physical Education Federal University of Santa Catarina  Florianopolis Santa Catarina Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monique","family":"Matsuda","sequence":"additional","affiliation":[{"name":"Laboratory of Investigation in Ophthalmology (LIM\u201033), Division of Ophthalmology, Faculty of Medicine University of S\u00e3o Paulo  S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00f4nica V.","family":"Marquezini","sequence":"additional","affiliation":[{"name":"Pro \u2010 Sangue Foundation, S\u00e3o Paulo and Pathology Department, Faculty of Medicine University of S\u00e3o Paulo  S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriano Eduardo","family":"Lima\u2010Silva","sequence":"additional","affiliation":[{"name":"Human Performance Research Group, Academic Department of Physical Education (DAEFI) Federal University of Technology Parana  Curitiba Parana Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo","family":"Saldiva","sequence":"additional","affiliation":[{"name":"Institute of Advanced Studies University of S\u00e3o Paulo  S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7026-8422","authenticated-orcid":false,"given":"Michael S.","family":"Koehle","sequence":"additional","affiliation":[{"name":"School of Kinesiology University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0407-9620","authenticated-orcid":false,"given":"R\u00f4mulo","family":"Bertuzzi","sequence":"additional","affiliation":[{"name":"Endurance Performance Research Group (GEDAE\u2010USP), School of Physical Education and Sport University of S\u00e3o Paulo  S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/oem.56.8.535"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atmosenv.2017.03.051"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365\u2010201X.1998.0331e.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-5919(02)00034-0"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e3181dbece1"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1989.67.3.1106"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.resp.2017.08.012"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010020\u201058253\u20107"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.3109\/08958378.2011.604106"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1123\/ijspp.8.2.111"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0192419"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00395\u2010014\u20100413\u20101"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1123\/ijspp.2021\u20100133"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0277978"},{"volume-title":"Hapter 4, exercise hyperemia and regulation of tissue oxygenation during muscular activity","year":"2011","author":"Korthuis R. J.","key":"e_1_2_8_16_1"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2018.04.040"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1159\/000194544"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0b013e3181b84a85"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1161\/hc0402.104118"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/00913847.1983.11708486"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2020.126817"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1975.39.4.633"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d4521"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/0-387-27023-X_40"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100043\u2010121147"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00305.2021"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00136.2013"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchf.2015.07.018"},{"volume-title":"WHO global air quality guidelines: Particulate matter (PM2.5 and PM10), ozone, nitrogen dioxide, sulfur dioxide and carbon monoxide","year":"2021","author":"World Health Organization","key":"e_1_2_8_30_1"}],"container-title":["Physiological Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.14814\/phy2.70408","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T12:16:09Z","timestamp":1754914569000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.14814\/phy2.70408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":29,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.14814\/phy2.70408"],"URL":"https:\/\/doi.org\/10.14814\/phy2.70408","archive":["Portico"],"relation":{},"ISSN":["2051-817X","2051-817X"],"issn-type":[{"type":"print","value":"2051-817X"},{"type":"electronic","value":"2051-817X"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"2024-12-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70408"}}