{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T11:10:15Z","timestamp":1758885015941,"version":"3.44.0"},"reference-count":33,"publisher":"Wiley","issue":"18","license":[{"start":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T00:00:00Z","timestamp":1758240000000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["GPIN 105424\u201012"],"award-info":[{"award-number":["GPIN 105424\u201012"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiological Reports"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The purpose of the study was to determine if sensory electrical stimulation (SES), below motor threshold, would reduce spinal excitability via reciprocal inhibition (RI) and determine if any changes were sex\u2010related. Eighteen healthy participants (11 males and 7 females) participated in a pre\u2010post comparison study. The Hoffmann (H\u2010) reflex was elicited to assess the spinal excitability of Flexor Carpi Radialis (FCR) and the influence of RI from Extensor Carpi Radialis Longus (ECRL) on FCR using a paired conditioning pulse paradigm. A 15\u2010min bout of SES (4 pulse bursts at 100\u2009Hz) was applied to ECRL, and the H\u2010reflexes were measured at 0\u2010 and 20\u2010min post SES. A linear mixed model regression analysis was performed to evaluate the effects of stimulus order, conditioning, sex, and time on the FCR H\u2010reflex. All participants experienced RI from the conditioning pulses, with females having significantly greater suppression than males (mean difference; MD\u2009=\u20090.026). For males, SES produced a depression in FCR excitability (MD\u2009=\u20090.023 at time 0; MD\u2009=\u20090.015 at 20\u2009min post\u2010SES) with no changes in RI. SES had no effect on FCR excitability or RI in females. The potential for SES to produce changes in antagonist excitability was sex\u2010related, which may have important rehabilitation considerations.<\/jats:p>","DOI":"10.14814\/phy2.70520","type":"journal-article","created":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T08:47:54Z","timestamp":1758271674000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Spinal excitability following sensory electrical stimulation of the upper limb"],"prefix":"10.14814","volume":"13","author":[{"given":"Devin","family":"Box","sequence":"first","affiliation":[{"name":"School of Kinesiology Western University  London Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua W.","family":"Cohen","sequence":"additional","affiliation":[{"name":"School of Kinesiology Western University  London Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanya D.","family":"Ivanova","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences Western University  London Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Jenkins","sequence":"additional","affiliation":[{"name":"Department of Clinical Neurological Sciences, Schulich School of Medicine and Dentistry Western University  London Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anita","family":"Christie","sequence":"additional","affiliation":[{"name":"School of Kinesiology Western University  London Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1117-2935","authenticated-orcid":false,"given":"S. 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