{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T00:27:38Z","timestamp":1788049658234,"version":"build-2784847793"},"reference-count":52,"publisher":"Wiley","issue":"17","license":[{"start":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T00:00:00Z","timestamp":1757635200000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiological Reports"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This study investigated the acute effect of maximal sprint exercise on dynamic cerebral autoregulation (dCA). Twenty\u2010one healthy young adults (22.9\u2009\u00b1\u20093.0\u2009years) completed a single experimental visit where dCA was assessed at rest and 25\u2009min following an all\u2010out 30\u2010s Wingate Anaerobic Test (WAnT). Forced oscillations in mean arterial pressure (MAP) during 5\u2009min of repeated sit\u2010stands, performed at 0.05\u2009Hz, were used to determine dCA. Middle cerebral artery blood velocity (MCAv) was measured using transcranial Doppler ultrasonography, and beat\u2010to\u2010beat blood pressure using finger plethysmography. dCA was analyzed using: (1) transfer function analysis and (2) a novel directional sensitivity metric (\u0394MCAv\n                    <jats:sub>T<\/jats:sub>\n                    \/\u0394MAP\n                    <jats:sub>T<\/jats:sub>\n                    ) for each MAP direction. There were no pre versus post\u2010WAnT differences in gain (0.73\u2009\u00b1\u20090.30 vs. 0.69\u2009\u00b1\u20090.21\u2009cm.s\n                    <jats:sup>\u22121<\/jats:sup>\n                    \/mmHg,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.49), normalized gain (1.10\u2009\u00b1\u20090.41 vs. 1.20\u2009\u00b1\u20090.33%\/mmHg,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.19), phase (0.98\u2009\u00b1\u20090.22 vs. 1.05\u2009\u00b1\u20090.24\u2009rad,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.18), or coherence (0.82\u2009\u00b1\u20090.13 vs. 0.90\u2009\u00b1\u20090.12,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.08). Pre\u2010exercise, \u0394MCAv\n                    <jats:sub>T<\/jats:sub>\n                    \/\u0394MAP\n                    <jats:sub>T<\/jats:sub>\n                    was significantly higher during acute decreases versus increases in MAP (1.05\u2009\u00b1\u20090.37 vs. 0.87\u2009\u00b1\u20090.31\u2009cm.s\n                    <jats:sup>\u22121<\/jats:sup>\n                    \/mmHg,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.034), and this persisted post\u2010exercise (0.93\u2009\u00b1\u20090.23 vs. 0.81\u2009\u00b1\u20090.25\u2009cm.s\n                    <jats:sup>\u22121<\/jats:sup>\n                    \/mmHg,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.017). \u0394MCAv\n                    <jats:sub>T<\/jats:sub>\n                    \/\u0394MAP\n                    <jats:sub>T<\/jats:sub>\n                    in either MAP direction was unaffected by the WAnT (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.15). These novel findings suggest that dCA was unaltered 25\u2009min following maximal sprint exercise in healthy young adults, while providing further support for hysteresis in the cerebral pressure\u2010flow relationship.\n                  <\/jats:p>","DOI":"10.14814\/phy2.70550","type":"journal-article","created":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T06:28:36Z","timestamp":1757744916000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["The acute effect of maximal sprint exercise on dynamic cerebral autoregulation in healthy young adults"],"prefix":"10.14814","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4808-6512","authenticated-orcid":false,"given":"M. E.","family":"Weston","sequence":"first","affiliation":[{"name":"THRIVE Laboratory, Department of Physiology School of Medicine, Trinity College Dublin  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4860-7470","authenticated-orcid":false,"given":"E. L.","family":"Curtin","sequence":"additional","affiliation":[{"name":"THRIVE Laboratory, Department of Physiology School of Medicine, Trinity College Dublin  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8775-0909","authenticated-orcid":false,"given":"P.","family":"Buys","sequence":"additional","affiliation":[{"name":"THRIVE Laboratory, Department of Physiology School of Medicine, Trinity College Dublin  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3497-1628","authenticated-orcid":false,"given":"N.","family":"Gildea","sequence":"additional","affiliation":[{"name":"THRIVE Laboratory, Department of Physiology School of Medicine, Trinity College Dublin  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1984-9250","authenticated-orcid":false,"given":"M.","family":"Ega\u00f1a","sequence":"additional","affiliation":[{"name":"THRIVE Laboratory, Department of Physiology School of Medicine, Trinity College Dublin  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,12]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.20.1.45"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.14814\/phy2.15384"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2008.07.048"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00854.2014"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00257.2024"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.26.5.834"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00790.2016"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10286-023-00986-2"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1113\/EP091703"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.14814\/phy2.14458"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.14814\/phy2.14367"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X241235878"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11883-018-0739-5"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00022.2020"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.90822.2008"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X15626425"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2011.69"},{"key":"e_1_2_12_19_1","volume-title":"Statistical power analysis for the behavioural sciences","author":"Cohen J.","year":"1977"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X17691986"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00384.2003"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00474.2018"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.557132"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.2040-4603.2019.tb00083.x"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1139\/apnm-2012-0444"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00376.2014"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6579\/ad0425"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00653.2021"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.14814\/phy2.14430"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.14814\/phy2.13984"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X241247633"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00269.2021"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X221104868"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1113\/expphysiol.2013.075333"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X221142527"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00010.2018"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X221119760"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00498.2024"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X231203475"},{"key":"e_1_2_12_40_1","doi-asserted-by":"crossref","unstructured":"Pecanha T. 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