{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T05:55:49Z","timestamp":1790142949707,"version":"4.0.1"},"reference-count":27,"publisher":"Wiley","issue":"24","license":[{"start":{"date-parts":[[2025,12,28]],"date-time":"2025-12-28T00:00:00Z","timestamp":1766880000000},"content-version":"vor","delay-in-days":27,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiological Reports"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Obesity is linked to structural and functional cardiac changes. This study assessed the impact of body mass index (BMI) on left ventricular (LV) function. A cross\u2010sectional study included 100 adults (50 obese and 50 nonobese), matched for age and sex. Echocardiographic parameters, end\u2010diastolic volume (EDV), end\u2010systolic volume (ESV), ejection fraction (EF), E\/A, E\/e ratios, Interventricular Septal thickness in Diastole (IVSd), stroke volume (SV), and cardiac output (CO), were measured by a blinded cardiologist using American Society of Echocardiography (guidelines. Spearman's correlation and multivariable regression evaluated associations between BMI and LV parameters. Obese participants had higher EDV (100.0\u2009\u00b1\u200923.3 vs. 84.6\u2009\u00b1\u200925.8\u2009mL), ESV (35.6\u2009\u00b1\u200910.0 vs. 30.4\u2009\u00b1\u200912.5\u2009mL), IVSd (9.33\u2009\u00b1\u20091.53 vs. 8.37\u2009\u00b1\u20090.91\u2009mm), and SV (67.7\u2009\u00b1\u200915.2 vs. 57.8\u2009\u00b1\u200913.9\u2009mL) than nonobese participants (all\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05). EF and E\/A ratio were similar. BMI correlated positively with EDV and ESV, negatively with E\/A ratio, and independently predicted higher EDV and ESV. Obesity is associated with increased LV volumes, septal thickness, and diastolic dysfunction while preserving systolic function, highlighting the importance of early cardiac evaluation in obese adults.\n                  <\/jats:p>","DOI":"10.14814\/phy2.70705","type":"journal-article","created":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T06:09:44Z","timestamp":1766988584000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effects of body mass index on left ventricular function: An echocardiographic comparison between obese and nonobese individuals"],"prefix":"10.14814","volume":"13","author":[{"given":"Nowrin","family":"Kashem","sequence":"first","affiliation":[{"name":"Department of Physiology Sylhet MAG Osmani Medical College  Sylhet Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Foysal","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Pharmacology Sylhet MAG Osmani Medical College  Sylhet Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumona","family":"Tanu","sequence":"additional","affiliation":[{"name":"Department of Physiology Sylhet MAG Osmani Medical College  Sylhet Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anamur","family":"Rahman","sequence":"additional","affiliation":[{"name":"Department of Cardiology Sylhet MAG Osmani Medical College  Sylhet Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rehana","family":"Sultana","sequence":"additional","affiliation":[{"name":"Department of Physiology Sylhet MAG Osmani Medical College  Sylhet Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeasmin","family":"Jui","sequence":"additional","affiliation":[{"name":"Department of Physiology Sylhet MAG Osmani Medical College  Sylhet Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9558-0594","authenticated-orcid":false,"given":"Md","family":"Asaduzzaman","sequence":"additional","affiliation":[{"name":"Department of Medicine Sylhet MAG Osmani Medical College Hospital  Sylhet 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