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While pharmacological therapies have advanced, the effect of dietary timing, particularly breakfast skipping, on disease course remains unclear. We conducted a retrospective cohort study using the JMDC database (2015\u20132023), which contains claims and annual health checkup data from about 8.17 million insured individuals. We identified 1645 UC patients who initiated corticosteroid therapy within 1\u2009year after diagnosis and were followed for at least 3\u2009years. Breakfast skipping was defined as skipping breakfast more than three times per week. The primary outcome was steroid withdrawal, defined as discontinuation of corticosteroid prescriptions. Logistic regression models estimated odds ratios (ORs) and 95% confidence intervals (CIs) for steroid withdrawal according to breakfast habits. Among 1645 patients, 303 (18.4%) reported skipping breakfast. Steroid withdrawal occurred in 543 patients (33.0%), including 108 (35.6%) in the breakfast skipping group and 435 (32.4%) in the breakfast consuming group. In fully adjusted models accounting for 5\u2010aminosalicylic acid and immunosuppressant use, breakfast skipping was associated with higher odds of steroid withdrawal (OR 1.52, 95% CI 1.08\u20132.14). These findings suggest that meal timing may influence sustained remission in UC.<\/jats:p>","DOI":"10.14814\/phy2.70708","type":"journal-article","created":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T12:33:32Z","timestamp":1766752412000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Breakfast skipping and steroid withdrawal in ulcerative colitis: A population\u2010based study in Japan"],"prefix":"10.14814","volume":"13","author":[{"given":"Hiroshi","family":"Fukuda","sequence":"first","affiliation":[{"name":"Faculty of Pharmaceutical Sciences Teikyo Heisei University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haru","family":"Miyagi","sequence":"additional","affiliation":[{"name":"Faculty of Pharmaceutical Sciences Teikyo Heisei University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5236-5160","authenticated-orcid":false,"given":"Kenta","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Faculty of Pharmaceutical Sciences Teikyo Heisei University  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2015.05.012"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2014.04.014"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.01.040"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2016.05.009"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ecco\u2010jcc\/jjac054"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ\u201019\u20101059"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114522000356"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/1751\u20102980.12910"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41522\u2010024\u201000520\u2010w"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu11020387"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/jgf2.422"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n1554"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2024.1342787"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2019.02.019"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384\u2010023\u201004417\u20106"}],"container-title":["Physiological Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.14814\/phy2.70708","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/full-xml\/10.14814\/phy2.70708","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.14814\/phy2.70708","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T06:46:30Z","timestamp":1771310790000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.14814\/phy2.70708"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":15,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10.14814\/phy2.70708"],"URL":"https:\/\/doi.org\/10.14814\/phy2.70708","archive":["Portico"],"relation":{},"ISSN":["2051-817X","2051-817X"],"issn-type":[{"value":"2051-817X","type":"print"},{"value":"2051-817X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"2025-11-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70708"}}