{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T23:11:50Z","timestamp":1786576310691,"version":"build-2736575974"},"reference-count":41,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T00:00:00Z","timestamp":1771286400000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100015103","name":"Japan Racing Association","doi-asserted-by":"publisher","award":["2019\u20102844\u201001"],"award-info":[{"award-number":["2019\u20102844\u201001"]}],"id":[{"id":"10.13039\/100015103","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiological Reports"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    This study tested the hypothesis that 6\u2009weeks of high\u2010intensity interval training (HIIT) would induce greater physiological adaptations than moderate\u2010intensity continuous training (MICT) in Thoroughbred horses. Seven untrained horses completed two distance\u2010matched treadmill training protocols (three sessions per week) in a randomized crossover design, separated by a three\u2010month washout: MICT (6\u2009min at 70% ) and HIIT (6\u2009\u00d7\u2009[30\u2009s at 100%  with 30\u2009s at 30% ]). Incremental exercise tests were conducted at weeks 0, 3, and 6 to assess exercise performance and physiological responses. Mixed\u2010effects models were used to analyze the effects of time, protocol, and their interaction (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05). After 6\u2009weeks, HIIT elicited greater improvements than MICT in run distance to exhaustion (+29% vs. +4.5%), speed at  (+9.8% vs. +2.4%), and speed at maximal heart rate (+15% vs. +4.3%). Speed at 10\u2009mmol\/L of plasma lactate increased only after HIIT (+13% vs. +6.0%). Both protocols similarly improved  (+13%) and maximal cardiac output (+7%\u20138%). In conclusion, despite being matched for total running distance, HIIT induced superior improvements in performance, cardiovascular function, and lactate kinetics compared with MICT, highlighting training intensity as a key determinant of training adaptations in horses.\n                  <\/jats:p>","DOI":"10.14814\/phy2.70785","type":"journal-article","created":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T05:32:36Z","timestamp":1771392756000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Physiological adaptations to 6\u2009weeks of high\u2010intensity interval and moderate\u2010intensity continuous training in horses: A randomized crossover study"],"prefix":"10.14814","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1992-6634","authenticated-orcid":false,"given":"Kazutaka","family":"Mukai","sequence":"first","affiliation":[{"name":"Sports Science Division Equine Research Institute, Japan 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