{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T01:40:50Z","timestamp":1777945250429,"version":"3.51.4"},"reference-count":63,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T00:00:00Z","timestamp":1771977600000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiological Reports"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Orthostatic intolerance is the inability to maintain upright posture, a key manifestation of autonomic dysfunction that can lead to orthostatic hypotension (OH). We aimed to investigate orthostatic blood pressure (BP) changes among cohorts living in Ekiti State and to explore plausible underlying factors. We encompassed 140 participants (28% male; 72% female; age range: 18\u201370\u2009years) in our preliminary study. Socio\u2010demographic and anthropometric indices were collected using appropriate tools. Orthostatic responses were assessed at baseline, standing, and sitting following standardized protocols. Systolic (BP) decreased significantly by 4% after 1\u2010min standing (130\u2009\u00b1\u200922\u2009mmHg) compared to baseline (137\u2009\u00b1\u200920\u2009mmHg). Diastolic (BP) increased significantly by 6.1% at 3\u2009min (87\u2009\u00b1\u200913\u2009mmHg) and 4.8% at 5\u2009min (86\u2009\u00b1\u200912\u2009mmHg) compared to baseline (82\u2009\u00b1\u200911\u2009mmHg) (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). Occupation (traders) and education level (secondary) are positively associated with mean arterial pressure (MAP) at 1\u2010 and 3\u2010min standing times (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05). Orthostatic MAP at 1, 3, and 5\u2009min correlated negatively with height but positively with body mass index (BMI), hip, and waist circumference (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.05). These preliminary findings suggest a potential role for body composition and lifestyle in regulating autonomic cardiovascular function in response to postural changes.\n                  <\/jats:p>","DOI":"10.14814\/phy2.70792","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T13:59:56Z","timestamp":1772978396000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Orthostatic blood pressure changes among adults in Ekiti state, Nigeria: Impact of socio\u2010demographic, anthropometric, and biophysical factors"],"prefix":"10.14814","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3005-331X","authenticated-orcid":false,"given":"Oyesanmi A.","family":"Fabunmi","sequence":"first","affiliation":[{"name":"Section Sports Medicine, Faculty of Health Sciences University of Pretoria  Hatfield South Africa"},{"name":"Health\u2010Awareness, Exercise and Cardio\u2010Immunologic Research Unit (HECIRU), Department of Physiology, College of Medicine Ekiti State University  Ado\u2010Ekiti Ekiti State Nigeria"},{"name":"Sport Exercise Medicine and Lifestyle Institute (SEMLI), Faculty of Health Sciences University of Pretoria  Hatfield South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayowa J.","family":"Adeniyi","sequence":"additional","affiliation":[{"name":"Departments of Physiology Federal University of Health Sciences  Otukpo Benue Nigeria"},{"name":"Departments of Physiology, School of Medicine and Pharmacy University of Rwanda  Kigali Rwanda"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Lenting","sequence":"additional","affiliation":[{"name":"Section Sports Medicine, Faculty of Health Sciences University of Pretoria  Hatfield South Africa"},{"name":"Sport Exercise Medicine and Lifestyle Institute (SEMLI), Faculty of Health Sciences University of Pretoria  Hatfield South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thulani","family":"Masilela","sequence":"additional","affiliation":[{"name":"Section Sports Medicine, Faculty of Health Sciences University of Pretoria  Hatfield South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1058-6992","authenticated-orcid":false,"given":"Dina C. (Christa)","family":"Janse van Rensburg","sequence":"additional","affiliation":[{"name":"Section Sports Medicine, Faculty of Health Sciences University of Pretoria  Hatfield South Africa"},{"name":"Sport Exercise Medicine and Lifestyle Institute (SEMLI), Faculty of Health Sciences University of Pretoria  Hatfield South Africa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,2,25]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2025.e42315"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.47672\/ajhmn.909"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41371-022-00673-1"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.37349\/emed.2024.00242"},{"key":"e_1_2_11_6_1","doi-asserted-by":"crossref","first-page":"24","DOI":"10.59566\/IJBS.2022.18024","article-title":"Modulatory role of pre\u2010exercise water ingestion on metabolic, cardiovascular and autonomic responses to prolonged exercise in young mildly active male students","volume":"18","author":"Adeniyi M.","year":"2022","journal-title":"International Journal of Biomedical Science: IJBS"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010022\u201009644\u20105"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/3192149"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.123.030696"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1249\/01.MSS.0000078924.61453.FB"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.24018\/ejmed.2023.5.3.1735"},{"key":"e_1_2_11_12_1","unstructured":"DeMers D. &Wachs D.(2019).Physiology Mean Arterial Pressure. 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