{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T05:28:54Z","timestamp":1786685334184,"version":"build-2736575974"},"reference-count":65,"publisher":"Wiley","issue":"15","license":[{"start":{"date-parts":[[2026,8,9]],"date-time":"2026-08-09T00:00:00Z","timestamp":1786233600000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiological Reports"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Exercise and dietary factors play an important role in shaping the metabolic profile of skeletal muscle. This study compared the effects of 12\u2009weeks of high\u2010intensity interval training (HIIT) with a normal diet (ND) or a high\u2010fat diet (HFD) on food and energy intake, as well as the metabolic profile of the gastrocnemius muscle in male rats. Thirty\u2010two Wistar rats were assigned to four groups (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u20098): normal diet control (NDC), high\u2010fat diet control (HFDC), HIIT+ND, and HIIT+HFD. Our findings demonstrated that HIIT decreased gastrocnemius muscle mass and the levels of beta\u2010alanine, glycine, serine, tyrosine, and fructose 6\u2010phosphate, while increasing glutamic acid levels. The HIIT+ND group exhibited significantly lower lactic acid levels than the other groups and lower threonine levels than the NDC and HFDC groups. Food and energy intake increased to a lesser extent in the HFDC and HIIT+HFD groups than in the ND and HIIT+ND groups. These findings indicate that HIIT exerts a predominant effect on metabolic regulation and can attenuate metabolic disturbances independently of diet. However, HIIT under a ND significantly affects certain glycolytic metabolites, including lactic acid.\n                  <\/jats:p>","DOI":"10.14814\/phy2.70802","type":"journal-article","created":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T06:11:05Z","timestamp":1786342265000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["High\u2010intensity interval training has a greater effect on metabolic profiles than the dietary composition in male rats"],"prefix":"10.14814","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-7236-1836","authenticated-orcid":false,"given":"Asiyeh","family":"Taji Tabas","sequence":"first","affiliation":[{"name":"Department of Sport Sciences, Faculty of Sport Sciences University of Birjand  Birjand Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5862-5490","authenticated-orcid":false,"given":"Marziyeh","family":"Saghebjoo","sequence":"additional","affiliation":[{"name":"Department of Sport Sciences, Faculty of Sport Sciences University of Birjand  Birjand Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3691-7641","authenticated-orcid":false,"given":"Reza","family":"Ghahremani","sequence":"additional","affiliation":[{"name":"Department of Sport Sciences, Faculty of Sport Sciences University of Birjand  Birjand Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5816-775X","authenticated-orcid":false,"given":"Mehdi","family":"Hedayati","sequence":"additional","affiliation":[{"name":"Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Molecular Biology, Research Institute for Endocrine Sciences Shahid Beheshti University of Medical Sciences  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,9]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1139\/apnm-2019-0352"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2018.01327"},{"key":"e_1_2_13_4_1","article-title":"A chronic high\u2010intensity interval training and diet\u2010induced obesity model to maximize exercise effort and induce physiologic changes in rats","volume":"194","author":"Arbus S. 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