{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T05:00:22Z","timestamp":1785214822366,"version":"3.55.0"},"reference-count":46,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T00:00:00Z","timestamp":1781654400000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["RGPIN\u20102020\u201005779"],"award-info":[{"award-number":["RGPIN\u20102020\u201005779"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiological Reports"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Menstrual cycle phase can influence indices of carbohydrate metabolism at rest and during exercise; however, limited research has explored whether there are menstrual phase\u2010specific differences in substrate metabolism in response to oral feeding. Using a within\u2010subjects crossover design, 15 eumenorrheic females completed a metabolic trial in the follicular phase (FP; day 7\u2009\u00b1\u20092) and the luteal phase (LP; day 22\u2009\u00b1\u20093; 8\u2009\u00b1\u20092\u2009days post\u2010ovulation) of a single menstrual cycle. Following an overnight fast, participants consumed a 75\u2009g glucose beverage enriched with a [U\u2010\n                    <jats:sup>13<\/jats:sup>\n                    C\n                    <jats:sub>6<\/jats:sub>\n                    ] D\u2010glucose tracer. Capillary glucose concentrations, exogenous glucose oxidation, expired carbon dioxide percentage (L%CO\n                    <jats:sub>2<\/jats:sub>\n                    ), and whole\u2010body carbohydrate and fat oxidation rates were measured fasted and across 3\u2010h postprandially. Peak 3\u2010h glucose concentration was higher in LP versus FP (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.04), with no differences in 3\u2010h mean glucose or incremental area under the curve between phases (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.34\u20130.63). Whole\u2010body (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.03) and exogenous carbohydrate oxidation (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.002) were higher in LP versus FP. %LCO\n                    <jats:sub>2<\/jats:sub>\n                    was elevated above fasting at all postprandial timepoints (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001) with no differences between phases (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.84). In conclusion, following an oral glucose load, peak blood glucose concentration and carbohydrate oxidation rates were elevated in LP versus FP. These findings suggest postprandial substrate utilization differs by menstrual cycle phase in healthy females.\n                  <\/jats:p>","DOI":"10.14814\/phy2.70876","type":"journal-article","created":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T06:27:38Z","timestamp":1781764058000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Higher whole\u2010body and exogenous postprandial glucose oxidation in the luteal versus follicular phase in healthy females"],"prefix":"10.14814","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3940-7655","authenticated-orcid":false,"given":"Alexa","family":"Govette","sequence":"first","affiliation":[{"name":"Faculty of Kinesiology and Physical Education University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel W. 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