{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T06:07:12Z","timestamp":1783836432347,"version":"3.55.0"},"reference-count":41,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T00:00:00Z","timestamp":1777939200000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["AI001150"],"award-info":[{"award-number":["AI001150"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiological Reports"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    We developed a noninvasive approach to measure vascular responses to sympathetic stimuli. We hypothesized that standing, handgrip exercise, or cold exposure would raise blood pressure (BP) and lower renal vascular conductance (RVC). BP was recorded continuously and renal arterial velocity was measured using renal Doppler ultrasound. Repeated measures one\u2010way ANOVA with Dunnett's post hoc test was used to compare BP during stimulation against baseline. Intraclass correlation analysis was used to compare first and second visits. Seven women and four men aged 29.9\u2009\u00b1\u20094.7\u2009years participated. On first visits, standing from supine raised systolic BP by 11.9\u2009\u00b1\u20092.6\u2009mmHg (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.0018) and diastolic BP by 15.0\u2009\u00b1\u20091.9\u2009mmHg (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.0001). Handgrip exercise raised systolic BP by 15.9\u2009\u00b1\u20094.1\u2009mmHg (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.0146) and decreased systolic RVC by 0.68\u2009\u00b1\u20090.26\u2009cm\/s\/mmHg (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.0049). Cold increased systolic BP by 27.8\u2009\u00b1\u20093.4\u2009mmHg (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.0001) and decreased systolic RVC by 0.32\u2009\u00b1\u20090.07\u2009cm\/s\/mmHg (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.0049). BP and RVC responses were similar from visit one to visit two; however, most outcome measurements were not correlated within individuals. These findings expand our understanding of vasoregulation in Black adults and guide studies to characterize vascular function in the future.\n                  <\/jats:p>","DOI":"10.14814\/phy2.70888","type":"journal-article","created":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T06:18:04Z","timestamp":1778048284000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Magnitude and variability of blood pressure and renal vascular conductance responses to postural changes, exercise, and cold in black adults: A pilot study"],"prefix":"10.14814","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-2155-3674","authenticated-orcid":false,"given":"Mohamed H.","family":"Ibrahim","sequence":"first","affiliation":[{"name":"Physiology Unit, Laboratory of Malaria and Vector Research National Institute of Allergy and Infectious Diseases  Rockville Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison J.","family":"McLure","sequence":"additional","affiliation":[{"name":"Physiology Unit, Laboratory of Malaria and Vector Research National Institute of Allergy and Infectious Diseases  Rockville Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary J.","family":"Jackson","sequence":"additional","affiliation":[{"name":"Physiology Unit, Laboratory of Malaria and Vector Research National Institute of Allergy and Infectious Diseases  Rockville Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5592-1547","authenticated-orcid":false,"given":"Brittany","family":"Harrison","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging Sciences NIH Clinical Center  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Brockley","sequence":"additional","affiliation":[{"name":"Physiology Unit, Laboratory of Malaria and Vector Research National Institute of Allergy and Infectious Diseases  Rockville Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4914-8180","authenticated-orcid":false,"given":"Elizabeth C.","family":"Jones","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging Sciences NIH Clinical Center  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1583-4783","authenticated-orcid":false,"given":"A. Parker","family":"Ruhl","sequence":"additional","affiliation":[{"name":"Physiology Unit, Laboratory of Malaria and Vector Research National Institute of Allergy and Infectious Diseases  Rockville Maryland USA"},{"name":"Critical Care Medicine and Pulmonary Branch National Heart Lung and Blood Institute  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4940-3305","authenticated-orcid":false,"given":"Hans C.","family":"Ackerman","sequence":"additional","affiliation":[{"name":"Physiology Unit, Laboratory of Malaria and Vector Research National Institute of Allergy and Infectious Diseases  Rockville Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,5]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748\u20101716.2010.02133.x"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.123.066003"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2016.00109"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00570.2018"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2016.02.009"},{"key":"e_1_2_13_7_1","volume-title":"Measuring Orthostatic Blood Pressure","author":"Centers of Disease Control and Prevention","year":"2017"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00403.2019"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00115.2007"},{"key":"e_1_2_13_10_1","volume-title":"StatPearls","author":"Delong C.","year":"2025"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2022.115386"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.12.6529"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0703052"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00322.2016"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.niox.2024.07.005"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102702.2005.01494.x"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00034.2024"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/diseases13060178"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2015.11.002"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.108.126391"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2005.06.006"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.197426"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.12659\/MSMBR.893397"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12576\u2010019\u201000669\u20106"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10286\u2010002\u20100059\u20101"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.71.5.1185"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcm.2016.02.012"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00152.2024"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.1161\/hy09t1.095205"},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2025.103251"},{"key":"e_1_2_13_31_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.101.8.862"},{"key":"e_1_2_13_32_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00214.2003"},{"key":"e_1_2_13_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-200105000-00011"},{"key":"e_1_2_13_34_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200102083440603"},{"key":"e_1_2_13_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/jch.13018"},{"key":"e_1_2_13_36_1","volume-title":"StatPearls","author":"Ringer M.","year":"2025"},{"key":"e_1_2_13_37_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00392.2022"},{"key":"e_1_2_13_38_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.100.23.2336"},{"key":"e_1_2_13_39_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00673.2022"},{"key":"e_1_2_13_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10286\u2010022\u201000872\u20103"},{"key":"e_1_2_13_41_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00151.2023"},{"key":"e_1_2_13_42_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.9.5.429"}],"container-title":["Physiological Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.14814\/phy2.70888","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/full-xml\/10.14814\/phy2.70888","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.14814\/phy2.70888","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T05:11:54Z","timestamp":1783833114000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.14814\/phy2.70888"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5]]},"references-count":41,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.14814\/phy2.70888"],"URL":"https:\/\/doi.org\/10.14814\/phy2.70888","archive":["Portico"],"relation":{},"ISSN":["2051-817X","2051-817X"],"issn-type":[{"value":"2051-817X","type":"print"},{"value":"2051-817X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5]]},"assertion":[{"value":"2026-01-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70888"}}