{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T05:00:18Z","timestamp":1785214818991,"version":"3.55.0"},"reference-count":34,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T00:00:00Z","timestamp":1782432000000},"content-version":"vor","delay-in-days":25,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["2017\u201004519"],"award-info":[{"award-number":["2017\u201004519"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["2021\u201000091"],"award-info":[{"award-number":["2021\u201000091"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005247","name":"University of British Columbia","doi-asserted-by":"publisher","award":["F20\u201006008"],"award-info":[{"award-number":["F20\u201006008"]}],"id":[{"id":"10.13039\/501100005247","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiological Reports"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    We tested the hypothesis that exercising while breathing real\u2010world ozone (O\n                    <jats:sub>3<\/jats:sub>\n                    ) concentrations impairs pulmonary and cardiovascular function in individuals with exercise\u2010induced bronchoconstriction (EIB) and that repeated exposures induce acclimation. Participants completed consecutive 30\u2010min cycling sessions breathing room air (RA) and 170\u2009ppb O\n                    <jats:sub>3<\/jats:sub>\n                    . A mixed\u2010effects model and ANOVA were used. Sixteen individuals (50% male) with mild\u2013moderate EIB completed the study. O\n                    <jats:sub>3<\/jats:sub>\n                    exposure produced pulmonary impairment on Day 2 in forced expiratory volume in 1\u2009s (Estimate\u2009=\u2009\u22125.1, 95% CI: \u22128.5 to \u22121.7,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.003), forced vital capacity (Estimate\u2009=\u2009\u22124.0, 95% CI: \u22127.1 to \u22120.9,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.008), and forced expiratory flow in the midportion of vital capacity (Estimate\u2009=\u2009\u22126.7, 95% CI: \u221212.7 to \u22120.7, p\u2009=\u20090.008). Minute ventilation was lower on Days 3 and 4 in O\n                    <jats:sub>3<\/jats:sub>\n                    ,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.007 and\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.001. Diastolic blood pressure was lowest on Day 2 under O\n                    <jats:sub>3<\/jats:sub>\n                    , 58\u2009mmHg (95% CI: 52, 64) versus RA, 63\u2009mmHg (95% CI: 58, 69), and a significant overall lower HR in O\n                    <jats:sub>3<\/jats:sub>\n                    was found across all visits,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.032. These findings demonstrate a significant difference in pulmonary and cardiovascular responses to O\n                    <jats:sub>3<\/jats:sub>\n                    compared to RA, but no statistical evidence of acclimation.\n                  <\/jats:p>","DOI":"10.14814\/phy2.70977","type":"journal-article","created":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T08:08:08Z","timestamp":1782461288000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pulmonary and cardiovascular responses to repeated ozone exposure during exercise in adults with exercise\u2010induced bronchoconstriction"],"prefix":"10.14814","volume":"14","author":[{"given":"Patric Emerson","family":"Oliveira Gon\u00e7alves","sequence":"first","affiliation":[{"name":"School of Kinesiology, Faculty of Education The University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-6140-6484","authenticated-orcid":false,"given":"Bennett","family":"Stothers","sequence":"additional","affiliation":[{"name":"School of Kinesiology, Faculty of Education The University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andy","family":"Hung","sequence":"additional","affiliation":[{"name":"School of Kinesiology, Faculty of Education The University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9 Casanova","family":"Silveira","sequence":"additional","affiliation":[{"name":"School of Physical Education and Sport University of S\u00e3o Paulo  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Owen Drake","family":"Harris","sequence":"additional","affiliation":[{"name":"School of Kinesiology, Faculty of Education The University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tessa","family":"van de Kerkhof","sequence":"additional","affiliation":[{"name":"Radboud Universiteit  Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadine","family":"Borduas\u2010Dedekind","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Science The University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew William","family":"Sheel","sequence":"additional","affiliation":[{"name":"School of Kinesiology, Faculty of Education The University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7026-8422","authenticated-orcid":false,"given":"Michael Stephen","family":"Koehle","sequence":"additional","affiliation":[{"name":"School of Kinesiology, Faculty of Education The University of British Columbia  Vancouver British Columbia Canada"},{"name":"Division of Sport &amp; Exercise Medicine, Faculty of Medicine The University of British Columbia  Vancouver British Columbia 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