{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T21:51:51Z","timestamp":1790718711057,"version":"4.1.0"},"reference-count":13,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T00:00:00Z","timestamp":1783728000000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiological Reports"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    To investigate the effects of acute hypoxia on uphill running and physiological responses during a 12\u2010min uphill time trial in trained trail runners and to assess potential sex differences. Thirteen trained trail runners (six females) completed a 12\u2010min treadmill uphill time trial (+12% incline) in normoxia and simulated hypoxia (~2500\u2009m). Performance, physiological, and perceptual responses were recorded. Hypoxia reduced distance covered (\u221215%), speed (\u221215%), and power output (\u22128.5%) (all\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001), while increasing respiratory exchange ratio and blood lactate concentration. Relative performance decrements were similar between sexes. Acute hypoxia impairs uphill running performance and increases metabolic strain irrespective of sex.\n                  <\/jats:p>","DOI":"10.14814\/phy2.70996","type":"journal-article","created":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T04:26:41Z","timestamp":1783830401000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Acute hypoxia impairs uphill running performance and alters metabolic responses in adult trained trail runners: A pilot study"],"prefix":"10.14814","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0588-0871","authenticated-orcid":false,"given":"Diego","family":"Ja\u00e9n\u2010Carrillo","sequence":"first","affiliation":[{"name":"Department of Sport Science University of Innsbruck  Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Coralie","family":"Gobbo","sequence":"additional","affiliation":[{"name":"Department of Sport Science University of Innsbruck  Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Girard","sequence":"additional","affiliation":[{"name":"School of Human Sciences, Department of Sport Science, Exercise and Health University of Western Australia  Perth Western Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe","family":"Garc\u00eda\u2010Pinillos","sequence":"additional","affiliation":[{"name":"Department of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS) University of Granada  Granada Spain"},{"name":"Department of Physical Education, Sport and Recreation Universidad de La Frontera  Temuco Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,11]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1123\/IJSPP.2025\u20100579"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1152\/AJPREGU.00155.2002"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.3758\/BF03193146"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.GAITPOST.2018.11.037"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/S004210050138\/METRICS"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1152\/JAPPL.1988.64.4.1486"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1123\/ijspp.2021\u20100451"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1123\/IJSPP.2024\u20100354"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/S00421\u2010007\u20100457\u20100\/FIGURES\/5"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/S40279\u2010023\u201001954\u20106\/FIGURES\/3"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1055\/A\u20101096\u20100980\/ID\/R7964\u20100019\/BIB"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/17461391.2021.1966104"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1123\/IJSPP.2025\u20100382"}],"container-title":["Physiological Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.14814\/phy2.70996","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/full-xml\/10.14814\/phy2.70996","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/pdf\/10.14814\/phy2.70996","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T04:43:03Z","timestamp":1784090583000},"score":1,"resource":{"primary":{"URL":"https:\/\/physoc.onlinelibrary.wiley.com\/doi\/10.14814\/phy2.70996"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":13,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.14814\/phy2.70996"],"URL":"https:\/\/doi.org\/10.14814\/phy2.70996","archive":["Portico"],"relation":{},"ISSN":["2051-817X","2051-817X"],"issn-type":[{"value":"2051-817X","type":"print"},{"value":"2051-817X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"2026-05-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70996"}}