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However, some mechanical and physiological responses underlying this task remain incompletely understood. This study characterized mechanical responses (force, velocity, and power) and regional muscle oxygen saturation (rSmO\n                    <jats:sub>2<\/jats:sub>\n                    ) in the vastus lateralis (VL) and biceps brachii (BB) during field\u2010based tethered repeated\u2010sprint exercise (RSE). Associations between muscle oxygenation and mechanical performance, as well as post\u2010exercise rSmO\n                    <jats:sub>2<\/jats:sub>\n                    , heart rate (HR), and blood lactate (LAC), were also examined. Ten professional soccer players performed a tethered Running Anaerobic Sprint Test (6\u2009\u00d7\u200935\u2010m all\u2010out sprints separated by 10\u2010s intervals), while mechanical variables and rSmO\n                    <jats:sub>2<\/jats:sub>\n                    were continuously recorded. Muscle oxygenation differed according to muscle function throughout exercise and recovery. The VL exhibited greater deoxygenation during sprints, whereas the BB showed a more preserved oxygenation profile. Associations between rSmO\n                    <jats:sub>2<\/jats:sub>\n                    and mechanical performance were observed only during the fifth and sixth sprints. Furthermore, only VL integrated rSmO\n                    <jats:sub>2<\/jats:sub>\n                    was positively correlated with the velocity fatigue index, whereas BB oxygenation provided complementary information on the physiological adjustments associated with RSE. Post\u2010exercise HR and LAC were not correlated with rSmO\n                    <jats:sub>2<\/jats:sub>\n                    in both muscles. Simultaneous assessment of locomotor and non\u2010locomotor muscles provides complementary insights into fatigue development and post\u2010exercise recovery RSE.\n                  <\/jats:p>","DOI":"10.14814\/phy2.71054","type":"journal-article","created":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T05:10:37Z","timestamp":1786597837000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Integrating mechanical, physiological, and muscle oxygenation responses during field\u2010based tethered repeated\u2010sprint exercise in male professional soccer players"],"prefix":"10.14814","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1178-570X","authenticated-orcid":false,"given":"F\u00falvia Barros","family":"Manchado\u2010Gobatto","sequence":"first","affiliation":[{"name":"Laboratory of Applied Sport Physiology \u2010 LAFAE School of Applied Sciences, University of Campinas \u2010 UNICAMP  Limeira Sao 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