{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T06:49:09Z","timestamp":1792133349353,"version":"4.4.0"},"reference-count":52,"publisher":"Wiley","issue":"20","license":[{"start":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T00:00:00Z","timestamp":1792022400000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["physoc.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Physiological Reports"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Handgrip strength is a simple and objective measure of muscle function, increasingly associated with physical and psychological health. However, data regarding its link to anxiety and depression in young adults remain limited. The aim of this study was to assess handgrip strength in healthy university students and examine its association with symptoms of anxiety and depression. This cross\u2010sectional study included 216 undergraduate students (mean age: 20.6\u2009\u00b1\u20094.7\u2009years). Handgrip strength of each participant was measured using a digital hand dynamometer. Symptoms of anxiety and depression were assessed using the GAD\u20107 (Generalized Anxiety Disorder\u20107) and the PHQ\u20109 (Patient Health Questionnaire\u20109), respectively. Pearson correlations and independent sample\n                    <jats:italic>t<\/jats:italic>\n                    \u2010tests were used for statistical analysis. Handgrip strength showed a small but statistically significant negative correlation with PHQ\u20109 (left hand:\n                    <jats:italic>r<\/jats:italic>\n                    \u2009=\u2009\u22120.148,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.030) and GAD\u20107 (left hand:\n                    <jats:italic>r<\/jats:italic>\n                    \u2009=\u2009\u22120.185,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.006) scores. These associations were stronger in female participants. Anxiety and depression scores were strongly positively correlated (\n                    <jats:italic>r<\/jats:italic>\n                    \u2009=\u20090.705,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). The results of this study indicate lower handgrip strength was associated with higher anxiety and depression symptoms in healthy university students, especially in female students. However, further longitudinal studies are needed to establish causality.\n                  <\/jats:p>","DOI":"10.14814\/phy2.71143","type":"journal-article","created":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T06:29:46Z","timestamp":1792132186000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association between handgrip strength and symptoms of anxiety and depression among university students: A cross\u2010sectional study"],"prefix":"10.14814","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-4279-3866","authenticated-orcid":false,"given":"Liyan","family":"Khadeeja","sequence":"first","affiliation":[{"name":"RAK College of Medical Sciences RAK Medical and Health Sciences University  Ras Al Khaimah United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7195-6945","authenticated-orcid":false,"given":"B. K. Manjunatha","family":"Goud","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, RAK College of Medical Sciences RAK Medical and Health Sciences University  Ras Al Khaimah United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1539-6162","authenticated-orcid":false,"given":"Rajani","family":"Dube","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, RAKCOMS RAK Medical and Health Sciences University  Ras Al Khaimah United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9379-7447","authenticated-orcid":false,"given":"Subhranshu Sekhar","family":"Kar","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, RAKCOMS RAK Medical and Health Sciences University  Ras Al Khaimah United Arab 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