{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T15:36:03Z","timestamp":1759073763631,"version":"3.44.0"},"reference-count":108,"publisher":"Canadian Science Publishing","issue":"4","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Psychiatry Neurosci"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:p> In the field of schizophrenia research, as in other areas of psychiatry, there is a sense of frustration that greater advances have not been made over the years, calling into question existing research strategies. Arguably, many purported gains claimed by research have been \u201clost in translation,\u201d resulting in limited impact on diagnosis and treatment in the clinical setting. There are exceptions; for example, we would argue that different lines of preclinical and clinical research have substantially altered how we look at antipsychotic dosing. While this story remains a work in progress, advances \u201cfound in translation\u201d have played an important role. Detailing these changes, the present paper speaks to a body of evidence that has already shifted clinical practice and raises questions that may further alter the manner in which antipsychotics have been administered over the last 6 decades. <\/jats:p>","DOI":"10.1503\/jpn.130191","type":"journal-article","created":{"date-parts":[[2014,6,25]],"date-time":"2014-06-25T13:21:50Z","timestamp":1403702510000},"page":"223-231","source":"Crossref","is-referenced-by-count":13,"title":["2012 CCNP Innovations Award Paper: Antipsychotic dosing: found in translation"],"prefix":"10.1139","volume":"39","author":[{"given":"Gary","family":"Remington","sequence":"first","affiliation":[{"name":"Department of Psychiatry, University of Toronto, Toronto, Ont."},{"name":"Institute of Medical Science, University of Toronto, Toronto, Ont."},{"name":"Centre for Addiction and Mental Health (CAMH), Toronto, Ont."},{"name":"Campbell Family Mental Health Research Institute, Toronto, Ont., 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