{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T19:25:51Z","timestamp":1781205951691,"version":"3.54.1"},"reference-count":52,"publisher":"Canadian Science Publishing","issue":"4","license":[{"start":{"date-parts":[[2023,7,4]],"date-time":"2023-07-04T00:00:00Z","timestamp":1688428800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Psychiatry Neurosci"],"published-print":{"date-parts":[[2023,7,4]]},"abstract":"<jats:sec><jats:title>Background:<\/jats:title><jats:p> Deficient causality perception and attribution may underlie key symptoms of schizophrenia spectrum disorder (SSD), such as delusions and ideas of reference. Although transcranial direct current stimulation (tDCS) can increase the influence of spatial information on perceptual causality judgments among healthy participants, its effect among patients with SSD remains unknown. We sought to determine whether tDCS modulates the contribution of stimulus characteristics to perceptual causality judgments among patients with SSD; we predicted that right parietal tDCS would increase the influence of spatial stimulus characteristics on patients\u2019 causality perception. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p> Patients with SSD received frontal, parietal, frontoparietal and sham tDCS in 4 separate sessions. Pre- and post-tDCS, patients viewed video clips of ball A colliding with ball B. Spatial linearity (ball B\u2019s angle of egress) and temporal contiguity (delay between collision and ball B\u2019s movement) varied parametrically. After each launching event, patients rated perceived causality. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> Among 19 patients with SSD, we found a brain region\u2013dependent effect of tDCS regarding sensitivity to violations of spatial linearity. After right parietal anodal tDCS, the influence of angle variations on patients\u2019 perceptual causality judgments increased, reflected by a higher probability of perceived causality for stimuli with small angles and a lower probability of perceived causality for stimuli with high angles. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p> Transcranial direct current stimulation increased the influence of spatial stimulus characteristics on causality perception among patients with SSD. Future research should explore potential links between tDCS-induced changes in basic perceptual processes and clinical symptoms, such as delusions and ideas of reference. <\/jats:p><\/jats:sec>","DOI":"10.1503\/jpn.220184","type":"journal-article","created":{"date-parts":[[2023,7,4]],"date-time":"2023-07-04T14:15:23Z","timestamp":1688480123000},"page":"E245-E254","source":"Crossref","is-referenced-by-count":4,"title":["Improving causality perception judgments in schizophrenia spectrum disorder via transcranial direct current stimulation"],"prefix":"10.1139","volume":"48","author":[{"given":"Rasmus","family":"Sch\u00fclke","sequence":"first","affiliation":[{"name":"From the Department of Psychiatry, Social Psychiatry and Psychotherapy, Hannover Medical School, Hannover, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina V.","family":"Schmitter","sequence":"additional","affiliation":[{"name":"the Translational Neuroimaging Marburg (TNM-Lab), Department of 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