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Bonifacino JS, Glick BS (2004) The mechanisms of vesicle budding and fusion. <i>Cell <\/i>116: 153-166."},{"key":"2","unstructured":"2. Henquin JC (2011) The dual control of insulin secretion by glucose involves triggering and amplifying pathways in &beta; cells. <i>Diabetes Res Clin Pract <\/i>93: S27-S31."},{"key":"3","unstructured":"3. Straub SG, Sharp GWG (2004) Hypothesis: one rate-limiting step controls the magnitude of both phases of glucose-stimulated insulin secretion. <i>Am J Physiol Cell Physiol <\/i>287: C565-C571."},{"key":"4","unstructured":"4. Aizawa T, Komatsu M (2005) Rab27a: a new face in beta cell metabolism-secretion coupling. <i>J Clin Invest<\/i> 115: 227-230."},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Henquin JC (2000) Triggering and amplifying pathways of regulation of insulin secretion by glucose. <i>Diabetes<\/i> 49: 1751-1760.","DOI":"10.2337\/diabetes.49.11.1751"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Bratanova-Tochkova TK, Cheng H, Daniel S, Gunawardana S, Liu YJ, et al. (2002) Triggering and augmentation mechanisms, granule pools, and biphasic insulin secretion. <i>Diabetes <\/i>51: S83-S90.","DOI":"10.2337\/diabetes.51.2007.S83"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Sato Y, Aizawa T, Komatsu M, Okada N, Yamada T (1992) Dual functional role of membrane depolarization\/Ca<sup>2+<\/sup> influx in rat pancreatic B-cell. <i>Diabetes<\/i> 41: 438-443.","DOI":"10.2337\/diab.41.4.438"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Gembal M, Gilon P, Henquin JC (1992) Evidence that glucose can control insulin release independently from its action on ATP-sensitive K<sup>+<\/sup> channels in mouse B cells.<i> J Clin Invest<\/i> 89: 1288-1295.","DOI":"10.1172\/JCI115714"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. 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Lacy PE &amp; Kostianovsky M (1967) Method for the isolation of intact islets of Langerhans from the rat pancreas. <i>Diabetes<\/i> 16: 35-39.","DOI":"10.2337\/diab.16.1.35"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Komatsu M, Yokokawa N, Takeda T, Nagasawa Y, Aizawa T, et al. (1989) Pharmacological characterization of the voltage-dependent calcium channel of pancreatic B-cell. <i>Endocrinology<\/i> 125: 2008-2014.","DOI":"10.1210\/endo-125-4-2008"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Yada T, Sakurada M, Ishihara H, Nakata M, Shioda S, et al. (1997) Pituitary adenylate cyclase-activating polypeptide (PACAP) is an islet substance serving as an intra-islet amplifier of glucose-induced insulin secretion in rats. <i>J Physiol<\/i> 505: 319-328.","DOI":"10.1111\/j.1469-7793.1997.319bb.x"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. 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Straub SG, Yajima H, Komatsu M, Aizawa T, Sharp GWG (2002) The effects of cerulenin, an inhibitor of protein acylation, on the two phases of glucose-stimulated insulin secretion. <i>Diabetes<\/i> 51: S91-S95.","DOI":"10.2337\/diabetes.51.2007.S91"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Resh MD (2006) Use of analogs and inhibitors to study the functional significance of protein palmitoylation. <i>Methods<\/i> 40: 191-197.","DOI":"10.1016\/j.ymeth.2006.04.013"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Abdel-Ghany M, Sharp GWG, Straub SG (2010) Glucose stimulation of protein acylation in the pancreatic &beta;-cell. <i>Life Sci<\/i> 87: 667-671.","DOI":"10.1016\/j.lfs.2010.09.021"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Yamada S, Komatsu M, Sato Y, Yamauchi K, Aizawa T, et al. 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Uchida K, Tominaga M (2011) The role of thermosensitive TRP (transient receptor potential) channels in insulin secretion. <i>Endocr J<\/i> 58: 1021-1028.","DOI":"10.1507\/endocrj.EJ11-0130"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Komatsu M, Sato Y, Aizawa T, Hashizume K (2001) KATP channel-independent glucose action: an elusive pathway in stimulus-secretion coupling of pancreatic &beta;-cell. <i>Endocr J<\/i> 48: 275-288.","DOI":"10.1507\/endocrj.48.275"},{"key":"28","unstructured":"28. Aizawa T, Sato Y, Ishihara F, Taguchi N, Komatsu M, et al. (1994) ATP-sensitive K<sup>+<\/sup> channel-independent glucose action in rat pancreatic beta-cell. <i>Am J Physiol<\/i> 266: C622-C627."},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Aizawa T, Komatsu M, Asanuma N, Sato Y, Sharp GWG (1998) Glucose action &lsquo;beyond ionic events&rsquo; in the pancreatic &beta; cell. <i>Trends Pharmacol Sci <\/i>19: 496-499.","DOI":"10.1016\/S0165-6147(98)01273-5"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Ozaki N, Shibasaki T, Kashima Y, Miki T, Takahashi K, et al. (2000) cAMP-GEFII is a direct target of cAMP in regulated exocytosis. <i>Nat Cell Biol <\/i>2: 805-811.","DOI":"10.1038\/35041046"},{"key":"31","doi-asserted-by":"crossref","unstructured":"31. Grimberg A, Ferry RJ Jr., Kelly A, Koo-McCoy S, Polonsky K et al. (2001) Dysregulation of insulin secretion in children with congenital hyperinsulinism due to sulfonylurea receptor mutations. <i>Diabetes<\/i> 50: 322-328.","DOI":"10.2337\/diabetes.50.2.322"},{"key":"32","doi-asserted-by":"crossref","unstructured":"32. 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