{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T06:43:20Z","timestamp":1790145800219,"version":"4.0.1"},"reference-count":24,"publisher":"Japan Endocrine Society","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endocr J"],"published-print":{"date-parts":[[2014]]},"DOI":"10.1507\/endocrj.ej14-0004","type":"journal-article","created":{"date-parts":[[2014,5,21]],"date-time":"2014-05-21T23:05:01Z","timestamp":1400713501000},"page":"727-733","source":"Crossref","is-referenced-by-count":18,"title":["High serum parathyroid hormone and calcium are risk factors for hypertension in Japanese patients"],"prefix":"10.1507","volume":"61","author":[{"given":"Shusuke","family":"Yagi","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Medicine, The University of Tokushima Graduate School of Health Biosciences, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken-ichi","family":"Aihara","sequence":"additional","affiliation":[{"name":"Department of Medicine and Bioregulatory Sciences, The University of Tokushima Graduate School of Health Biosciences, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Kondo","sequence":"additional","affiliation":[{"name":"Department of Medicine and Bioregulatory Sciences, The University of Tokushima Graduate School of Health Biosciences, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Itsuro","family":"Endo","sequence":"additional","affiliation":[{"name":"Department of Medicine and Bioregulatory Sciences, The University of Tokushima Graduate School of Health Biosciences, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junko","family":"Hotchi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, The University of Tokushima Graduate School of Health Biosciences, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takayuki","family":"Ise","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, The University of Tokushima Graduate School of Health Biosciences, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Iwase","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, The University of Tokushima Graduate School of Health Biosciences, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masashi","family":"Akaike","sequence":"additional","affiliation":[{"name":"Department of Medical Education, The University of Tokushima Graduate School of Health Biosciences, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshio","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Department of Medicine and Bioregulatory Sciences, The University of Tokushima Graduate School of Health Biosciences, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masataka","family":"Sata","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, The University of Tokushima Graduate School of Health Biosciences, Tokushima 770-8503, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"386","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. No authors listed (1991) NIH conference. Diagnosis and management of asymptomatic primary hyperparathyroidism: consensus development conference statement. <i>Ann Intern Med<\/i> 114: 593-597.","DOI":"10.7326\/0003-4819-114-7-593"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. van Ballegooijen AJ, Reinders I, Visser M, Dekker JM, Nijpels G, et al. (2013) Serum parathyroid hormone in relation to all-cause and cardiovascular mortality: the Hoorn study. <i>J Clin Endocrinol Metab<\/i> 98: E638-645.","DOI":"10.1210\/jc.2012-4007"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. van Ballegooijen AJ, Visser M, Kestenbaum B, Siscovick DS, de Boer IH, et al. (2013) Relation of vitamin D and parathyroid hormone to cardiac biomarkers and to left ventricular mass (from the Cardiovascular Health Study). <i>Am J Cardiol<\/i> 111: 418-424.","DOI":"10.1016\/j.amjcard.2012.10.021"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Andersson P, Rydberg E, Willenheimer R (2004) Primary hyperparathyroidism and heart disease--a review. <i>Eur Heart J<\/i> 25: 1776-1787.","DOI":"10.1016\/j.ehj.2004.07.010"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Garcia de la Torre N, Wass JA, Turner HE (2003) Parathyroid adenomas and cardiovascular risk. <i>Endocr Relat Cancer<\/i> 10: 309-322.","DOI":"10.1677\/erc.0.0100309"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Pirro M, Manfredelli MR, Helou RS, Scarponi AM, Schillaci G, et al. (2012) Association of parathyroid hormone and 25-OH-vitamin D levels with arterial stiffness in postmenopausal women with vitamin D insufficiency. <i>J Atheroscler Thromb <\/i>19: 924-931.","DOI":"10.5551\/jat.13128"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. van Ballegooijen AJ, Visser M, Cotch MF, Arai AE, Garcia M, et al. (2013) Serum vitamin D and parathyroid hormone in relation to cardiac structure and function: The ICELAND-MI substudy of AGES-Reykjavik. <i>J Clin Endocrinol Metab<\/i> 98: 2544-2552.","DOI":"10.1210\/jc.2012-4252"},{"key":"8","unstructured":"8. Han D, Trooskin S, Wang X (2012) Prevalence of cardiovascular risk factors in male and female patients with primary hyperparathyroidism. <i>J Endocrinol Invest<\/i> 35: 548-552."},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Luigi P, Chiara FM, Laura Z, Cristiano M, Giuseppina C, et al. (2012) Arterial Hypertension, Metabolic Syndrome and Subclinical Cardiovascular Organ Damage in Patients with Asymptomatic Primary Hyperparathyroidism Before and After Parathyroidectomy: Preliminary Results. <i>Int J Endocrinol<\/i> 2012: 408295.","DOI":"10.1155\/2012\/408295"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Zhao G, Ford ES, Li C, Kris-Etherton PM, Etherton TD, et al. (2010) Independent associations of serum concentrations of 25-hydroxyvitamin D and parathyroid hormone with blood pressure among US adults. <i>J Hypertens<\/i> 28: 1821-1828.","DOI":"10.1097\/HJH.0b013e32833bc5b4"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Saleh F, Jorde R, Sundsfjord J, Haug E, Figenschau Y (2006) Causes of secondary hyperparathyroidism in a healthy population: The Troms&oslash; study. <i>J Bone Miner Metab<\/i> 24: 58-64.","DOI":"10.1007\/s00774-005-0647-y"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Jorde R, Svartberg J, Sundsfjord J (2005) Serum parathyroid hormone as a predictor of increase in systolic blood pressure in men. <i>J Hypertens<\/i> 23: 1639-1644.","DOI":"10.1097\/01.hjh.0000179764.40701.36"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Fraser WD (2009) Hyperparathyroidism. <i>Lancet<\/i> 374: 145-158.","DOI":"10.1016\/S0140-6736(09)60507-9"},{"key":"14","unstructured":"14. Leifsson BG, Ahr&eacute;n B (1996) Serum calcium and survival in a large health screening program. <i>J Clin Endocrinol Metab<\/i> 81: 2149-2153."},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Nilsson IL, Rastad J, Johansson K, Lind L (2001) Endothelial vasodilatory function and blood pressure response to local and systemic hypercalcemia. <i>Surgery<\/i> 130: 986-990.","DOI":"10.1067\/msy.2001.118368"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Jung J, Foroud TM, Eckert GJ, Flury-Wetherill L, Edenberg HJ, et al. (2009) Association of the calcium-sensing receptor gene with blood pressure and urinary calcium in African-Americans. <i>J Clin Endocrinol Metab<\/i> 94: 1042-1048.","DOI":"10.1210\/jc.2008-1861"},{"key":"17","unstructured":"17. Hulter HN, Melby JC, Peterson JC, Cooke CR (1986) Chronic continuous PTH infusion results in hypertension in normal subjects. <i>J Clin Hypertens<\/i> 2: 360-370."},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Schleiffer R, Bergmann C, Pernot F, Gairard A (1989) Parathyroid hormone acute vascular effect is mediated by decreased Ca2+ uptake and enhanced cAMP level. <i>Mol Cell Endocrinol <\/i>67: 63-71.","DOI":"10.1016\/0303-7207(89)90231-1"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Kosch M, Hausberg M, Vormbrock K, Kisters K, Gabriels G, et al. (2000) Impaired flow-mediated vasodilation of the brachial artery in patients with primary hyperparathyroidism improves after parathyroidectomy. <i>Cardiovasc Res<\/i> 47: 813-818.","DOI":"10.1016\/S0008-6363(00)00130-9"},{"key":"20","unstructured":"20. Gennari C, Nami R, Gonnelli S (1995) Hypertension and primary hyperparathyroidism: the role of adrenergic and renin-angiotensin-aldosterone systems. <i>Miner Electrolyte Metab<\/i> 21: 77-81."},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Mazzocchi G, Aragona F, Malendowicz LK, Nussdorfer GG (2001) PTH and PTH-related peptide enhance steroid secretion from human adrenocortical cells. <i>Am J Physiol Endocrinol Metab <\/i>280: E209-213.","DOI":"10.1152\/ajpendo.2001.280.2.E209"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Vlachakis ND, Frederics R, Valasquez M, Alexander N, Singer F, et al. (1982) Sympathetic system function and vascular reactivity in hypercalcemic patients. <i>Hypertension <\/i>4: 452-458.","DOI":"10.1161\/01.HYP.4.3.452"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. McCarron DA, Pingree PA, Rubin RJ, Gaucher SM, Molitch M, et al. (1980) Enhanced parathyroid function in essential hypertension: A homeostatic response to a urinary calcium leak. <i>Hypertension<\/i> 2: 162-168.","DOI":"10.1161\/01.HYP.2.2.162"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Cappuccio FP, Meilahn E, Zmuda JM, Cauley JA (1999) High blood pressure and bone-mineral loss in elderly white women: a prospective study. Study of Osteoporotic Fractures Research Group. <i>Lancet<\/i> 354: 971-975.","DOI":"10.1016\/S0140-6736(99)01437-3"}],"container-title":["Endocrine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/endocrj\/61\/7\/61_EJ14-0004\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T06:41:09Z","timestamp":1618296069000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/endocrj\/61\/7\/61_EJ14-0004\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":24,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.1507\/endocrj.ej14-0004","relation":{},"ISSN":["0918-8959","1348-4540"],"issn-type":[{"value":"0918-8959","type":"print"},{"value":"1348-4540","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}