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Seino Y (2004) Physiopathology and etiological mechanism involving type 2 diabetes mellitus. <i>Nihon Naika Gakkai Zasshi<\/i> 93: 1749-1760 (In Japanese).","DOI":"10.2169\/naika.93.1749"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Fukushima M, Suzuki H, Seino Y (2004) Insulin secretion capacity in the development from normal glucose tolerance to type 2 diabetes. <i>Diabetes Res Clin Pract<\/i> 66 Suppl 1: S37-43.","DOI":"10.1016\/j.diabres.2003.11.024"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Tanaka Y, Atsumi Y, Asahina T, Hosokawa K, Matsuoka K, et al. (1998) Usefulness of revised fasting plasma glucose criterion and characteristics of the insulin response to an oral glucose load in newly diagnosed Japanese diabetic subjects. <i>Diabetes Care<\/i> 21: 1133-1137.","DOI":"10.2337\/diacare.21.7.1133"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Owen SV, Froman RD (2005) Why carve up your continuous data? <i>Res Nurs Health<\/i> 28: 496-503.","DOI":"10.1002\/nur.20107"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Naggara O, Raymond J, Guilbert F, Roy D, Weill A, et al. (2011) Analysis by categorizing or dichotomizing continuous variables is inadvisable: an example from the natural history of unruptured aneurysms.<i> AJNR Am J Neuroradiol<\/i> 32: 437-440.","DOI":"10.3174\/ajnr.A2425"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Kashiwagi A, Kasuga M, Araki E, Oka Y, Hanafusa T, et al. (2012) International clinical harmonization of glycated hemoglobin in Japan : From Japan Diabetes Society to National Glycohemoglobin Standardization Program values. <i>J Diabetes Investig<\/i> 3: 39-40.","DOI":"10.1111\/j.2040-1124.2012.00207.x"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. 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Sakaue S, Ishimaru S, Ikeda D, Ohtsuka Y, Honda T, et al. (2007) Estimation of beta-cell function from the data of the oral glucose tolerance test. <i>Am J Physiol Endocrinol Metab<\/i> 292: E1575-E1580.","DOI":"10.1152\/ajpendo.00341.2006"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Matsuda M, DeFronzo RA (1999) Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. <i>Diabetes Care<\/i> 22: 1462-1470.","DOI":"10.2337\/diacare.22.9.1462"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Stancakova A, Javorsky M, Kuulasmaa T, Haffner SM, Kuusisto J, et al. (2009) Changes in insulin sensitivity and insulin release in relation to glycemia and glucose tolerance in 6,414 Finnish men. <i>Diabetes<\/i> 58: 1212-1221.","DOI":"10.2337\/db08-1607"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Oka R, Yagi K, Sakurai M, Nakamura K, Moriuchi T, et al. 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Kanauchi M, Nakajima M, Saito Y, Kanauchi K (2003) Pancreatic beta-cell function and insulin sensitivity in japanese subjects with impaired glucose tolerance and newly diagnosed type 2 diabetes mellitus. <i>Metabolism<\/i> 52: 476-481.","DOI":"10.1053\/meta.2003.50078"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Kendall DM, Cuddihy RM, Bergenstal RM (2009) Clinical application of incretin-based therapy: therapeutic potential, patient selection and clinical use. <i>Am J Med<\/i> 122: S37-50.","DOI":"10.1016\/j.amjmed.2009.03.015"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Weyer C, Bogardus C, Mott DM, Pratley RE (1999) The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. <i>J Clin Invest<\/i> 104: 787-794.","DOI":"10.1172\/JCI7231"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. Ferrannini E, Mari A (2004) Beta cell function and its relation to insulin action in humans: a critical appraisal. <i>Diabetologia<\/i> 47: 943-956.","DOI":"10.1007\/s00125-004-1381-z"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Utzschneider KM, Prigeon RL, Faulenbach MV, Tong J, Carr DB, et al. 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