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Kahn SE, Cooper ME, Del Prato S (2014) Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future. <i>Lancet <\/i>383: 1068-1083.","DOI":"10.1016\/S0140-6736(13)62154-6"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Del Prato S (2009) Role of glucotoxicity and lipotoxicity in the pathophysiology of Type 2 diabetes mellitus and emerging treatment strategies. <i>Diabet Med<\/i> 26: 1185-1192.","DOI":"10.1111\/j.1464-5491.2009.02847.x"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Kramer CK, Zinman B, Retnakaran R (2013) Short-term intensive insulin therapy in type 2 diabetes mellitus: a systematic review and meta-analysis. <i>Lancet Diabetes Endocrinol<\/i> 1: 28-34.","DOI":"10.1016\/S2213-8587(13)70006-8"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. 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(2014) Glucose-lowering rate influences cardiomyocyte apoptosis via ERK1\/2 pathway. <i>Chin J Endocrinol Metab<\/i> 30: 985-989 (In Chinese)."},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Wu W, Sun Z, Li Q, Wang M, Miao J,<i> et al<\/i>. (2012) Influence of the glucose-lowering rate on left ventricular function in patients with type 2 diabetes and coronary heart disease. <i>J Diabetes Complications<\/i> 26: 83-88.","DOI":"10.1016\/j.jdiacomp.2012.02.010"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Grunwald JE, Riva CE, Martin DB, Quint AR, Epstein PA (1987) Effect of an insulin-induced decrease in blood glucose on the human diabetic retinal circulation. <i>Ophthalmology <\/i>94: 1614-1620.","DOI":"10.1016\/S0161-6420(87)33257-9"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. 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