{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T16:24:03Z","timestamp":1784219043016,"version":"3.55.0"},"reference-count":29,"publisher":"Japan Endocrine Society","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endocr J"],"published-print":{"date-parts":[[2018]]},"DOI":"10.1507\/endocrj.ej18-0035","type":"journal-article","created":{"date-parts":[[2018,5,24]],"date-time":"2018-05-24T18:26:40Z","timestamp":1527186400000},"page":"869-875","source":"Crossref","is-referenced-by-count":8,"title":["Autonomic alterations as a clinical manifestation of encephalopathy associated with autoimmune thyroid disease"],"prefix":"10.1507","volume":"65","author":[{"given":"Maria","family":"Tomkins","sequence":"first","affiliation":[{"name":"Department of Endocrinology\/Diabetes Mellitus, Mater Misericordiae University Hospital, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"Cavalcoli","sequence":"additional","affiliation":[{"name":"Department of Endocrinology\/Diabetes Mellitus, Mater Misericordiae University Hospital, Dublin, Ireland"},{"name":"Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca\u2019 Granda Ospedale Maggiore Policlinico, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Stanley","sequence":"additional","affiliation":[{"name":"Department of Radiology, Mater Misericordiae University Hospital, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Killian","family":"O\u2019Rourke","sequence":"additional","affiliation":[{"name":"Department of Neurology, Dublin Neurological Institute, Mater Misericordiae University Hospital, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean","family":"Murphy","sequence":"additional","affiliation":[{"name":"Department of Medicine for the Older Person and Stroke Medicine, Mater Misericordiae University Hospital, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Lynch","sequence":"additional","affiliation":[{"name":"Department of Neurology, Dublin Neurological Institute, Mater Misericordiae University Hospital, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluca","family":"Tamagno","sequence":"additional","affiliation":[{"name":"Department of Endocrinology\/Diabetes Mellitus, Mater Misericordiae University Hospital, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"386","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1 Tamagno G, Celik Y, Sim\u00f3 R, Dihn\u00e9 M, Kimura K, et al. (2010) Encephalopathy associated with autoimmune thyroid disease in patients with Graves\u2019 disease: clinical manifestations, follow-up, and outcomes. BMC Neurol 10: 27.","DOI":"10.1186\/1471-2377-10-27"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2 Castillo P, Woodruff B, Caselli R, Vernino S, Lucchinetti C, et al. (2006) Steroid-responsive encephalopathy associated with autoimmune thyroiditis. Arch Neurol 63: 197\u2013202.","DOI":"10.1001\/archneur.63.2.197"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3 Ferracci F, Carnevale A (2006) The neurological disorder associated with thyroid autoimmunity. J Neurol 253: 975\u2013984.","DOI":"10.1007\/s00415-006-0170-7"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4 Dihn\u00e9 M, Schuier FJ, Schuier M, Cordes J, Hartung HP, et al. (2008) Hashimoto encephalopathy following iodine 131 (131 I) radiotherapy of Graves disease. Arch Neurol 65: 282\u2013283.","DOI":"10.1001\/archneurol.2007.49"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5 Gelosa G, Di Francesco JC, Tremolizzo L, Lanzani F, Rota S, et al. (2009) Autoimmune encephalopathy in Graves\u2019 disease: remission after total thyroidectomy. J Neurol Neurosurg Psychiatry 80: 698\u2013699.","DOI":"10.1136\/jnnp.2008.152413"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6 Tamagno G, Federspil G, Murialdo G (2006) Clinical and diagnostic aspects of encephalopathy associated with autoimmune thyroid disease (or Hashimoto\u2019s encephalopathy). Intern Emerg Med 1: 15\u201323.","DOI":"10.1007\/BF02934715"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7 Striano P, Pagliuca M, Andreone V, Zara F, Coppola A, et al. (2006) Unfavourable outcome of Hashimoto encephalopathy due to status epilepticus. One autopsy case. J Neurol 253: 248\u2013249.","DOI":"10.1007\/s00415-005-0925-6"},{"key":"8","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1212\/01.WNL.0000090462.62087.A1","volume":"61","author":"P Duffey","year":"2003","unstructured":"8 Duffey P, Yee S, Reid IN, Bridges LR (2003) Hashimoto\u2019s encephalopathy: postmortem findings after fatal status epilepticus. Neurology 61: 1124\u20131126.","journal-title":"Neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0028-3878","issn-type":"print"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9 de Holanda NC, de Lima DD, Cavalcanti TB, Lucena CS, Bandeira F (2011) Hashimoto\u2019s encephalopathy: systematic review of the literature and an additional case. J Neuropsychiatry Clin Neurosci 23: 384\u2013390.","DOI":"10.1176\/jnp.23.4.jnp384"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10 Mijajlovic M, Mirkovic M, Dackovic J, Zidverc-Trajkovic J, Sternic N (2010) Clinical manifestations, diagnostic criteria and therapy of Hashimoto\u2019s encephalopathy: report of two cases. J Neurol Sci 288: 194\u2013196.","DOI":"10.1016\/j.jns.2009.09.030"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11 Chong JY, Rowland LP, Utiger RD (2003) Hashimoto encephalopathy: syndrome or myth? Arch Neurol 60: 164\u2013171.","DOI":"10.1001\/archneur.60.2.164"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12 Sch\u00e4uble B, Castillo PR, Boeve BF, Westmoreland BF (2003) EEG findings in steroid-responsive encephalopathy associated with autoimmune thyroiditis. Clin Neurophysiol 114: 32\u201337.","DOI":"10.1016\/S1388-2457(02)00343-7"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13 Tamagno G, Gaoatswe G (2011) Time for the endocrinologists to expand their awareness of and contribution to the diagnosis and management of encephalopathy associated with autoimmune thyroid disease. Hormones (Athens) 10: 36\u201338.","DOI":"10.14310\/horm.2002.1298"},{"key":"14","doi-asserted-by":"publisher","unstructured":"14 Mocellin R, Walterfang M, Velakoulis D (2007) Hashimoto\u2019s encephalopathy: epidemiology, pathogenesis and management. CNS Drugs 21: 799\u2013811.","DOI":"10.2165\/00023210-200721100-00002"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15 Graus F, Titulaer MJ, Balu R, Benseler S, Bien CG, et al. (2016) A clinical approach to diagnosis of autoimmune encephalitis. Lancet Neurol 15: 391\u2013404.","DOI":"10.1016\/S1474-4422(15)00401-9"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16 Ferracci F, Bertiato G, Moretto G (2004) Hashimoto\u2019s encephalopathy: epidemiologic data and pathogenetic considerations. J Neurol Sci 217: 165\u2013168.","DOI":"10.1016\/j.jns.2003.09.007"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17 Fujii A, Yoneda M, Ito T, Yamamura O, Satomi S, et al. (2005) Autoantibodies against the amino terminal of alpha-enolase are a useful diagnostic marker of Hashimoto\u2019s encephalopathy. J Neuroimmunol 162: 130\u2013136.","DOI":"10.1016\/j.jneuroim.2005.02.004"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18 Ochi H, Horiuchi I, Araki N, Toda T, Araki T, et al. (2002) Proteomic analysis of human brain identifies alpha-enolase as a novel autoantigen in Hashimoto\u2019s encephalopathy. FEBS Lett 528: 197\u2013202.","DOI":"10.1016\/S0014-5793(02)03307-0"},{"key":"19","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1212\/01.WNL.0000048660.71390.C6","volume":"60","author":"F Ferracci","year":"2003","unstructured":"19 Ferracci F, Moretto G, Candeago RM, Cimini N, Conte F, et al. (2003) Antithyroid antibodies in the CSF: their role in the pathogenesis of Hashimoto\u2019s encephalopathy. Neurology 60: 712\u2013714.","journal-title":"Neurology","ISSN":"https:\/\/id.crossref.org\/issn\/0028-3878","issn-type":"print"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20 Ishikawa S, Aoki H, Akahane C, Shimada H, Takei Y, et al. (2001) Hypothalamic encephalitis with bradycardia. Intern Med 40: 805\u2013807.","DOI":"10.2169\/internalmedicine.40.805"},{"key":"21","unstructured":"21 Saffran L, Goldner BG, Adler H, Feingold BD, Feingold RM, et al. (1995) Asystole associated with herpes simplex encephalitis. J Invasive Cardiol 7: 152\u2013155."},{"key":"22","doi-asserted-by":"crossref","unstructured":"22 Hudspeth M, Brown E, Ragucci D, Dixon T, Turner R (2012) Severe pruritus and hypothermia as the primary manifestations of human herpes virus-6 encephalitis after pediatric cord blood transplantation. Bone Marrow Transplant 47: 153\u2013154.","DOI":"10.1038\/bmt.2011.25"},{"key":"23","doi-asserted-by":"crossref","unstructured":"23 Fukushima K, Yasaki M, Kaneko K, Fushimi T, Yamamoto K, et al. (2005) Nonparaneoplastic, nonherpetic limbic encephalitis with severe episodic hypothermia: a case report. Eur Neurol 54: 170\u2013174.","DOI":"10.1159\/000089938"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24 Schott JM (2006) Another case of voltage-gated potassium channel antibody-related encephalopathy? Eur Neurol 55: 110.","DOI":"10.1159\/000092787"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25 Jacob S, Irani SR, Rajabally YA, Grubneac A, Walters RJ, et al. (2008) Hypothermia in VGKC antibody-associated limbic encephalitis. J Neurol Neurosurg Psychiatry 79: 202\u2013204.","DOI":"10.1136\/jnnp.2007.130039"},{"key":"26","doi-asserted-by":"publisher","unstructured":"26 Henchey R, Cibula J, Helveston W, Malone J, Gilmore RL (1995) Electroencephalographic findings in Hashimoto\u2019s encephalopathy. Neurology 45: 977\u2013981.","DOI":"10.1212\/WNL.45.5.977"},{"key":"27","doi-asserted-by":"crossref","unstructured":"27 Kothbauer-Margreiter I, Sturzenegger M, Komor J, Baumgartner R, Hess CW (1996) Encephalopathy associated with Hashimoto thyroiditis: diagnosis and treatment. J Neurol 243: 585\u2013593.","DOI":"10.1007\/BF00900946"},{"key":"28","unstructured":"28 Goldenberg MM (2012) Multiple sclerosis review. P T 37: 175\u2013184."},{"key":"29","doi-asserted-by":"crossref","unstructured":"29 Doherty CP, Schlossmacher M, Torres N, Bromfield E, Samuels MA, et al. (2002) Hashimoto\u2019s encephalopathy mimicking Creutzfeldt-Jakob disease: brain biopsy findings. J Neurol Neurosurg Psychiatry 73: 601\u2013602.","DOI":"10.1136\/jnnp.73.5.601-a"}],"container-title":["Endocrine Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/endocrj\/65\/8\/65_EJ18-0035\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,18]],"date-time":"2019-10-18T09:40:31Z","timestamp":1571391631000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/endocrj\/65\/8\/65_EJ18-0035\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":29,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.1507\/endocrj.ej18-0035","relation":{},"ISSN":["0918-8959","1348-4540"],"issn-type":[{"value":"0918-8959","type":"print"},{"value":"1348-4540","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018]]}}}