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(1990) Thyroidal and peripheral production of 3,5,3'-triiodothyronine in humans by multicompartmental analysis. Am J Physiol 258: E715\u2013E726."},{"key":"2","doi-asserted-by":"crossref","unstructured":"2 Ito M, Miyauchi A, Morita S, Kudo T, Nishihara E, et al. (2012) TSH-suppressive doses of levothyroxine are required to achieve preoperative native serum triiodothyronine levels in patients who have undergone total thyroidectomy. Eur J Endocrinol 167: 373\u2013378.","DOI":"10.1530\/EJE-11-1029"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3 Gullo D, Latina A, Frasca F, Le Moli R, Pellegriti G, et al. (2011) Levothyroxine monotherapy cannot guarantee euthyroidism in all athyreotic patients. PLoS One 6: e22552.","DOI":"10.1371\/journal.pone.0022552"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4 Hoermann R, Midgley JE, Giacobino A, Eckl WA, Wahl HG, et al. (2014) Homeostatic equilibria between free thyroid hormones and pituitary thyrotropin are modulated by various influences including age, body mass index and treatment. Clin Endocrinol (Oxf) 81: 907\u2013915.","DOI":"10.1111\/cen.12527"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5 Ito M, Kawasaki M, Danno H, Kohsaka K, Nakamura T, et al. (2019) Serum thyroid hormone balance in levothyroxine monotherapy-treated patients with atrophic thyroid after radioiodine treatment for Graves\u2019 disease. Thyroid 29: 1364\u20131370.","DOI":"10.1089\/thy.2019.0135"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6 Ito M, Miyauchi A, Kang S, Hisakado M, Yoshioka W, et al. (2015) Effect of the presence of remnant thyroid tissue on the serum thyroid hormone balance in thyroidectomized patients. Eur J Endocrinol 173: 333\u2013340.","DOI":"10.1530\/EJE-15-0138"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7 Harada A, Nomura E, Nishimura K, Ito M, Yoshida H, et al. (2019) Type 1 and type 2 iodothyronine deiodinases in the thyroid gland of patients with huge goitrous Hashimoto\u2019s thyroiditis. Endocrine 64: 584\u2013590.","DOI":"10.1007\/s12020-019-01855-7"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8 Kawasaki M, Ito M, Danno H, Kousaka K, Nakamura T, et al. (2019) The association between thyroid hormone balance and thyroid volume in patients with Hashimoto thyroiditis. Endocr J 66: 763\u2013768.","DOI":"10.1507\/endocrj.EJ19-0063"},{"key":"9","unstructured":"9 Kitaoka M, Suzuki S (ed) (2016) Thyroid Ultrasound \u2013 A guidebook for diagnosis and management (3rd edition). Japan Association of Breast and Thyroid Sonology. Nankodo, Tokyo, Japan (In Japanese)."},{"key":"10","unstructured":"10 Murakami Y, Takamatsu J, Sakane S, Kuma K, Ohsawa N (1996) Changes in thyroid volume in response to radioactive iodine for Graves\u2019 hyperthyroidism correlated with activity of thyroid-stimulating antibody and treatment outcome. J Clin Endocrinol Metab 81: 3257\u20133260."},{"key":"11","doi-asserted-by":"crossref","unstructured":"11 Bianco AC, Salvatore D, Gereben B, Berry MJ, Larsen PR (2002) Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. Endocr Rev 23: 38\u201389.","DOI":"10.1210\/edrv.23.1.0455"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12 Maia AL, Kim BW, Huang SA, Harney JW, Larsen PR (2005) Type 2 iodothyronine deiodinase is the major source of plasma T3 in euthyroid humans. J Clin Invest 115: 2524\u20132533.","DOI":"10.1172\/JCI25083"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13 Hoermann R, Midgley JE, Larisch R, Dietrich JW (2015) Integration of peripheral and glandular regulation of triiodothyronine production by thyrotropin in untreated and thyroxine-treated subjects. Horm Metab Res 47: 674\u2013680.","DOI":"10.1055\/s-0034-1398616"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14 Kanou Y, Hishinuma A, Tsunekawa K, Seki K, Mizuno Y, et al. (2007) Thyroglobulin gene mutations producing defective intracellular transport of thyroglobulin are associated with increased thyroidal type 2 iodothyronine deiodinase activity. J Clin Endocrinol Metab 92: 1451\u20131457.","DOI":"10.1210\/jc.2006-1242"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15 Celi FS, Coppotelli G, Chidakel A, Kelly M, Brillante BA, et al. (2008) The role of type 1 and type 2 5'-deiodinase in the pathophysiology of the 3,5,3'-triiodothyronine toxicosis of McCune-Albright syndrome. J Clin Endocrinol Metab 93: 2383\u20132389.","DOI":"10.1210\/jc.2007-2237"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16 Ito M, Toyoda N, Nomura E, Takamura Y, Amino N, et al. (2011) Type 1 and type 2 iodothyronine deiodinases in the thyroid gland of patients with 3,5,3'-triiodothyronine-predominant Graves\u2019 disease. Eur J Endocrinol 164: 95\u2013100.","DOI":"10.1530\/EJE-10-0736"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17 Werneck de Castro JP, Fonseca TL, Ueta CB, McAninch EA, Abdalla S, et al. (2015) Differences in hypothalamic type 2 deiodinase ubiquitination explain localized sensitivity to thyroxine. J Clin Invest 125: 769\u2013781.","DOI":"10.1172\/JCI77588"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18 Escobar-Morreale HF, Obreg\u00f3n MJ, Escobar del Rey F, Morreale de Escobar G (1995) Replacement therapy for hypothyroidism with thyroxine alone does not ensure euthyroidism in all tissues, as studied in thyroidectomized rats. J Clin Invest 96: 2828\u20132838.","DOI":"10.1172\/JCI118353"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19 Ito M, Miyauchi A, Hisakado M, Yoshioka W, Ide A, et al. 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