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(2012) Antithyroid drug-induced hematopoietic damage: a retrospective cohort study of agranulocytosis and pancytopenia involving 50,385 patients with Graves\u2019 disease. J Clin Endocrinol Metab 97: E49\u2013E53.","DOI":"10.1210\/jc.2011-2221"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2 Moore FD (1946) Toxic manifestations of thiouracil therapy. J Am Med Assoc 130: 315\u2013319.","DOI":"10.1001\/jama.1946.02870060001001"},{"key":"3","doi-asserted-by":"publisher","unstructured":"3 Specht NW, Boehme EJ (1952) Death due to agranulocytosis induced by methimazoke therapy. JAMA 149: 1010\u20131011.","DOI":"10.1001\/jama.1952.72930280001009"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4 Nakamura H, Miyauchi A, Miyawaki N, Imagawa J (2013) Analysis of 754 cases of antithyroid drug-induced agranulocytosis over 30 years in Japan. 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(2009) Methimazole-induced agranulocytosis in patients with Graves\u2019 disease is more frequent with an initial dose of 30 mg daily than with 15 mg daily. Thyroid 19: 559\u2013563.","DOI":"10.1089\/thy.2008.0364"},{"key":"12","doi-asserted-by":"publisher","unstructured":"12 Alexander EK, Pearce EN, Brent GA, Brown RS, Chen H, et al. (2017) 2017 Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and the postpartum. Thyroid 27: 315\u2013389.","DOI":"10.1089\/thy.2016.0457"},{"key":"13","doi-asserted-by":"publisher","unstructured":"13 Cooper DS (1999) The side effects of antithyroid drugs. The Endocrinologist 9: 457\u2013467.","DOI":"10.1097\/00019616-199911000-00008"},{"key":"14","doi-asserted-by":"publisher","unstructured":"14 Yang J, Zhu YJ, Zhong JJ, Zhang J, Weng WW, et al. (2016) Characteristics of antithyroid drug-induced agranulocytosis in patients with hyperthyroidism: a retrospective analysis of 114 cases in a single institution in China involving 9690 patients referred for radioiodine treatment over 15 years. Thyroid 26: 627\u2013633.","DOI":"10.1089\/thy.2015.0439"},{"key":"15","doi-asserted-by":"publisher","unstructured":"15 Sato S, Noh JY, Sato S, Suzuki M, Yasuda S, et al. (2015) Comparison of efficacy and adverse effects between methimazole 15 mg+inorganic iodine 38 mg\/day and methimazole 30 mg\/day as initial therapy for Graves\u2019 disease patients with moderate to severe hyperthyroidism. Thyroid 25: 43\u201350.","DOI":"10.1089\/thy.2014.0084"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16 Tamai H, Takaichi Y, Morita T, Komaki G, Matsubayashi S, et al. (1989) Methimazole-induced agranulocytosis in Japanese patients with Graves\u2019 disease. Clin Endocrinol (Oxf) 30: 525\u2013530.","DOI":"10.1111\/j.1365-2265.1989.tb01424.x"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17 Mutharasan P, Oatis W, Kwaan H, Molitch M (2012) Delayed anithyroid drug-induced agranulocytosis. Endocr Pract 18: e69\u2013e72.","DOI":"10.4158\/EP11339.CR"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18 Nakamura H, Ide A, Kudo T, Nishihara E, Ito M, et al. (2016) Periodic granulocyte count measuring is useful for detecting asymptomatic agranulocytosis in antithyroid drug-treated patients with Graves\u2019 disease. Eur Thyroid J 5: 253\u2013260.","DOI":"10.1159\/000448586"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19 Curtis BR (2017) Non-chemotherapy drug-induced neutropenia: key points to manage the challenges. 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