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Growth Horm IGF Res 57\u201358: 101392.","DOI":"10.1016\/j.ghir.2021.101392"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5 Melmed S (2019) Pathogenesis and diagnosis of growth hormone deficiency in adults. N Engl J Med 380: 2551\u20132562.","DOI":"10.1056\/NEJMra1817346"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6 Stanley T (2012) Diagnosis of growth hormone deficiency in childhood. Curr Opin Endocrinol Diabetes Obes 19: 47\u201352.","DOI":"10.1097\/MED.0b013e32834ec952"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7 Tornese G (2023) \u2018Growth hormone deficiency\u2019 or rather \u2018short stature unresponsive to stimulation tests\u2019? Arch Dis Child 108: 176\u2013177.","DOI":"10.1136\/archdischild-2021-323426"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8 Hizuka N (2007) Endocrine diseases: diagnosis and treatment of adult growth hormone insufficiency. Nihon Naibunpi Gakkai Zasshi 96: 1230\u20131234 (In Japanese).","DOI":"10.2169\/naika.96.1230"},{"key":"9","unstructured":"9  (2014) Information Center for Specific Pediatric Chronic Disease, Japan. Growth hormone deficiency. https:\/\/www.shouman.jp\/disease\/details\/05_04_006\/ accessed on February 20, 2024 (In Japanese)."},{"key":"10","unstructured":"10 Desrosiers P, O\u2019Brien F, Blethen S (2005) Patient outcomes in the GHMonitor: the effect of delivery device on compliance and growth. Pediatr Endocrinol Rev 2 Suppl 3: 327\u2013331."},{"key":"11","doi-asserted-by":"crossref","unstructured":"11 Cutfield WS, Derraik JG, Gunn AJ, Reid K, Delany T, et al. (2011) Non-compliance with growth hormone treatment in children is common and impairs linear growth. PLoS One 6: e16223.","DOI":"10.1371\/journal.pone.0016223"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12 Kaplowitz P, Manjelievskaia J, Lopez-Gonzalez L, Morrow CD, Pitukcheewanont P, et al. (2021) Economic burden of growth hormone deficiency in a US pediatric population. J Manag Care Spec Pharm 27: 1118\u20131128.","DOI":"10.18553\/jmcp.2021.21030"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13 Graham S, Weinman J, Auyeung V (2018) Identifying potentially modifiable factors associated with treatment non-adherence in paediatric growth hormone deficiency: a systematic review. Horm Res Paediatr 90: 221\u2013227.","DOI":"10.1159\/000493211"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14 Gomez R, Ahmed SF, Maghnie M, Li D, Tanaka T, et al. (2022) Treatment adherence to injectable treatments in pediatric growth hormone deficiency compared with injectable treatments in other chronic pediatric conditions: a systematic literature review. Front Endocrinol (Lausanne) 13: 795224.","DOI":"10.3389\/fendo.2022.795224"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15 Growth Hormone Research Society (2000) Consensus guidelines for the diagnosis and treatment of growth hormone (GH) deficiency in childhood and adolescence: summary statement of the GH Research Society. GH Research Society. J Clin Endocrinol Metab 85: 3990\u20133993.","DOI":"10.1210\/jc.85.11.3990"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16 Stagi S, Scalini P, Farello G, Verrotti A (2017) Possible effects of an early diagnosis and treatment in patients with growth hormone deficiency: the state of art. Ital J Pediatr 43: 81.","DOI":"10.1186\/s13052-017-0402-8"},{"key":"17","unstructured":"17 Miller BS, Rotenstein D, Deeb LC, Germak J, Wisniewski T (2014) Persistence with growth hormone therapy in pediatric patients. Am J Pharm Benefits 6: e9\u2013e17."},{"key":"18","doi-asserted-by":"crossref","unstructured":"18 Loftus J, Wogen J, Oliveri D, Benjumea D, Jhingran P, et al. (2022) Persistence with daily growth hormone among children and adolescents with growth hormone deficiency in the UK. Front Endocrinol (Lausanne) 13: 1014743.","DOI":"10.3389\/fendo.2022.1014743"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19 Nagai K, Tanaka T, Kodaira N, Kimura S, Takahashi Y, et al. (2021) Data resource profile: JMDC claims database sourced from health insurance societies. J Gen Fam Med 22: 118\u2013127.","DOI":"10.1002\/jgf2.422"},{"key":"20","unstructured":"20  (2024) https:\/\/www.fgs.or.jp\/business\/growth_hormone\/treatment_decision\/growth_hormone_short_stature\/chart.html accessed on July 4, 2024."},{"key":"21","unstructured":"22  (2021) https:\/\/www.stat.go.jp\/data\/kokusei\/2020\/kekka.html accessed on February 20, 2024."},{"key":"22","unstructured":"23 Tanaka T, Takano K, Haniu K, Nishi Y, Fujieda K, et al. (1998) Frequency of GH-treated GH-deficient children: analysis of registration system of the Foundation for Growth Science. Clinical Endocrinology 46: 1017\u20131023 (In Japanese)."},{"key":"23","doi-asserted-by":"crossref","unstructured":"24 Tanaka T (2022) Changes, limitations, and prospects of adult height in GH treatment for Japanese GHD patients. Clin Pediatr Endocrinol 31: 211\u2013224.","DOI":"10.1297\/cpe.2022-0034"},{"key":"24","doi-asserted-by":"crossref","unstructured":"25 Isojima T, Hasegawa T, Yokoya S, Tanaka T (2022) Demographic characteristics of children with growth hormone deficiency from 1996 to 2015 in Japan: 20 years of data from the foundation for growth science in Japan. Endocr J 69: 927\u2013939.","DOI":"10.1507\/endocrj.EJ21-0520"},{"key":"25","doi-asserted-by":"crossref","unstructured":"26 Tanaka T, Soneda S, Sato N, Kishi K, Noda M, et al. (2021) The boy:girl ratio of children diagnosed with growth hormone deficiency-induced short stature is associated with the boy:girl ratio of children visiting short stature clinics. Horm Res Paediatr 94: 211\u2013218.","DOI":"10.1159\/000518995"},{"key":"26","doi-asserted-by":"crossref","unstructured":"27 Marini MG, Chesi P, Mazzanti L, Guazzarotti L, Toni TD, et al. (2016) Stories of experiences of care for growth hormone deficiency: the CRESCERE project. Future Sci OA 2: Fso82.","DOI":"10.4155\/fso.15.82"},{"key":"27","doi-asserted-by":"crossref","unstructured":"28 Kremidas D, Wisniewski T, Divino VM, Bala K, Olsen M, et al. (2013) Administration burden associated with recombinant human growth hormone treatment: perspectives of patients and caregivers. J Pediatr Nurs 28: 55\u201363.","DOI":"10.1016\/j.pedn.2011.12.006"},{"key":"28","doi-asserted-by":"crossref","unstructured":"29 Bagnasco F, Di Iorgi N, Roveda A, Gallizia A, Haupt R, et al. (2017) Prevalence and correlates of adherence in children and adolescents treated with growth hormone: a multicenter Italian study. Endocr Pract 23: 929\u2013941.","DOI":"10.4158\/EP171786.OR"},{"key":"29","doi-asserted-by":"crossref","unstructured":"30 Bozzola M, Colle M, Halldin-Stenlid M, Larroque S, Zignani M (2011) Treatment adherence with the easypod<sup>TM<\/sup> growth hormone electronic auto-injector and patient acceptance: survey results from 824 children and their parents. 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